CRCGN010_HEPG2_24H:P23 Gene Set
Genes
38 genes differentially expressed following the CRCGN010_HEPG2_24H:P23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
4.07152
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.72811
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.65233
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.61176
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.55419
|
|
MCOLN1
|
mucolipin 1
|
3.53261
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.3938
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
3.26914
|
|
CRTAP
|
cartilage associated protein
|
3.22815
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.14737
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.91171
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.67797
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
2.67706
|
|
NOTCH1
|
notch 1
|
2.60309
|
|
GATA2
|
GATA binding protein 2
|
2.43163
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.39439
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.35513
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
2.2551
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.25171
|
|
MAP7
|
microtubule-associated protein 7
|
2.13372
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.02385
|
|
SFTPB
|
surfactant protein B
|
2.01184
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.48206
|
|
PLK1
|
polo-like kinase 1
|
-4.03875
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.93142
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.62682
|
|
DNM1L
|
dynamin 1-like
|
-3.61822
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.8656
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.68471
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.58195
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.42289
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.39551
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.34161
|
|
CCNB2
|
cyclin B2
|
-2.30417
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.25303
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.10873
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.04483
|
|
CCNB1
|
cyclin B1
|
-2.03766
|
