CRCGN010_HEPG2_24H:P24 Gene Set
Genes
52 genes differentially expressed following the CRCGN010_HEPG2_24H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
7.91947
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.71977
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
5.46253
|
|
EVL
|
Enah/Vasp-like
|
4.7659
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.5334
|
|
MAP7
|
microtubule-associated protein 7
|
4.4559
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.10401
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.05688
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.4777
|
|
CHN1
|
chimerin 1
|
3.37477
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.34081
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.28009
|
|
SFTPB
|
surfactant protein B
|
3.2172
|
|
PRR15L
|
proline rich 15-like
|
3.18888
|
|
CYCS
|
cytochrome c, somatic
|
3.06822
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.98795
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
2.81284
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
2.75904
|
|
GATA2
|
GATA binding protein 2
|
2.44532
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.4236
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.40334
|
|
RBKS
|
ribokinase
|
2.32293
|
|
HOXA10
|
homeobox A10
|
2.29808
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.14779
|
|
GPATCH8
|
G patch domain containing 8
|
2.12446
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.09724
|
|
TMEM50A
|
transmembrane protein 50A
|
2.08469
|
|
BAX
|
BCL2-associated X protein
|
2.07043
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.75036
|
|
ZNF586
|
zinc finger protein 586
|
-5.4143
|
|
TLR4
|
toll-like receptor 4
|
-4.98515
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.11377
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.96568
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.89524
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.77971
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.70871
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.64604
|
|
CDC20
|
cell division cycle 20
|
-3.61487
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.49697
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.35111
|
|
XPO7
|
exportin 7
|
-3.07732
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.98355
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.69841
|
|
GNAS
|
GNAS complex locus
|
-2.65691
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.64466
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.5944
|
|
DSG2
|
desmoglein 2
|
-2.4621
|
|
CYP27B1
|
cytochrome P450, family 27, subfamily B, polypeptide 1
|
-2.29636
|
|
CDK4
|
cyclin-dependent kinase 4
|
-2.16534
|
|
PLA2G15
|
phospholipase A2, group XV
|
-2.15565
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.14377
|
|
ZNF124
|
zinc finger protein 124
|
-2.13068
|
