| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN011_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 10.0 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.18225 |
| LCN2 | lipocalin 2 | 5.15075 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.53215 |
| NOTCH1 | notch 1 | 4.3513 |
| EPHB2 | EPH receptor B2 | 4.3293 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.2534 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.15595 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.05545 |
| MEF2C | myocyte enhancer factor 2C | 3.74278 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 3.6253 |
| ABHD6 | abhydrolase domain containing 6 | 3.38095 |
| EPN2 | epsin 2 | 3.365 |
| FASTKD5 | FAST kinase domains 5 | 3.24855 |
| COL11A1 | collagen, type XI, alpha 1 | 3.14197 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.0412 |
| CYCS | cytochrome c, somatic | 3.0245 |
| COMMD3-BMI1 | COMMD3-BMI1 readthrough | 2.91595 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.8756 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.7762 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.64017 |
| GPATCH8 | G patch domain containing 8 | 2.62472 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.57965 |
| JADE2 | jade family PHD finger 2 | 2.4602 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.40925 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.3988 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.28872 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 2.2657 |
| MEMO1 | mediator of cell motility 1 | 2.19975 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.1708 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.1425 |
| COQ8A | coenzyme Q8A | 2.11325 |
| KDSR | 3-ketodihydrosphingosine reductase | 2.10865 |
| DIPK1A | divergent protein kinase domain 1A | 2.107 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.0929 |
| FAM8A1 | family with sequence similarity 8, member A1 | 2.05935 |
| SLC25A46 | solute carrier family 25, member 46 | 2.02235 |
| RNF167 | ring finger protein 167 | 2.00295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -5.2171 |
| CDC20 | cell division cycle 20 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.3928 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.694 |
| USP6NL | USP6 N-terminal like | -3.3341 |
| GNAS | GNAS complex locus | -3.02489 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.98605 |
| ANO3 | anoctamin 3 | -2.89985 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.6888 |
| HMG20B | high mobility group 20B | -2.67188 |
| TLCD3A | TLC domain containing 3A | -2.473 |
| RPE65 | retinal pigment epithelium-specific protein 65kDa | -2.3924 |
| EDDM3A | epididymal protein 3A | -2.39007 |
| PRPF4 | pre-mRNA processing factor 4 | -2.35278 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -2.329 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 | -2.31505 |
| DUSP2 | dual specificity phosphatase 2 | -2.30665 |
| EDDM3B | epididymal protein 3B | -2.28005 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.2497 |
| CCN6 | cellular communication network factor 6 | -2.24495 |
| HOXD9 | homeobox D9 | -2.19715 |
| ZNF492 | zinc finger protein 492 | -2.19555 |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit | -2.1654 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -2.138 |
| ADAM7 | ADAM metallopeptidase domain 7 | -2.10995 |
| CRISP1 | cysteine-rich secretory protein 1 | -2.1071 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -2.09335 |
| DPPA4 | developmental pluripotency associated 4 | -2.09245 |
| DRD1 | dopamine receptor D1 | -2.09015 |
| LOC105379278 | uncharacterized LOC105379278 | -2.08345 |
| WWC2 | WW and C2 domain containing 2 | -2.06565 |
| MAGEB4 | melanoma antigen family B4 | -2.05555 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -2.0294 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.0258 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -2.0238 |
| TAGLN2 | transgelin 2 | -2.0228 |
| EMCN | endomucin | -2.01865 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -2.0162 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -2.01615 |
| HOXC5 | homeobox C5 | -2.00605 |
| DEFB126 | defensin, beta 126 | -2.00575 |
| BCAS3 | breast carcinoma amplified sequence 3 | -2.00415 |
