| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | picloram, technical grade 20.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN011_HEPG2_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.34105 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.9751 |
| LCN2 | lipocalin 2 | 4.74705 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.56707 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.3269 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.76665 |
| HDGFL3 | HDGF like 3 | 3.4663 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.2951 |
| MICALL1 | MICAL-like 1 | 3.22857 |
| PRKCH | protein kinase C, eta | 3.1001 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 2.9819 |
| PLSCR3 | phospholipid scramblase 3 | 2.80515 |
| GPATCH8 | G patch domain containing 8 | 2.74743 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.7236 |
| JADE2 | jade family PHD finger 2 | 2.64517 |
| WDR47 | WD repeat domain 47 | 2.6277 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.423 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.40935 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.28925 |
| SLFN12 | schlafen family member 12 | 2.2225 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 2.2022 |
| MCFD2 | multiple coagulation factor deficiency 2 | 2.10818 |
| CHN1 | chimerin 1 | 2.09275 |
| MAP7D1 | MAP7 domain containing 1 | 2.0822 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.07565 |
| HEATR3 | HEAT repeat containing 3 | 2.0641 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.049 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.04255 |
| CLEC16A | C-type lectin domain family 16, member A | 2.02175 |
| GRB10 | growth factor receptor-bound protein 10 | 2.01305 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.0122 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.25446 |
| USP6NL | USP6 N-terminal like | -5.6697 |
| LDHD | lactate dehydrogenase D | -4.8761 |
| CCNB1 | cyclin B1 | -4.8367 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.9374 |
| TWF2 | twinfilin actin binding protein 2 | -3.846 |
| RAI14 | retinoic acid induced 14 | -3.5068 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.9532 |
| RBM34 | RNA binding motif protein 34 | -2.83498 |
| HEATR1 | HEAT repeat containing 1 | -2.73795 |
| TLCD3A | TLC domain containing 3A | -2.67705 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -2.50795 |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | -2.46633 |
| SNTG1 | syntrophin, gamma 1 | -2.44565 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 | -2.41545 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 | -2.3784 |
| CRCP | CGRP receptor component | -2.31597 |
| UBL5 | ubiquitin-like 5 | -2.2244 |
| MTREX | Mtr4 exosome RNA helicase | -2.2202 |
| SHOX | short stature homeobox | -2.2038 |
| TP53 | tumor protein p53 | -2.10518 |
| HOXD11 | homeobox D11 | -2.0885 |
| OSTF1 | osteoclast stimulating factor 1 | -2.0705 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 | -2.0665 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | -2.06405 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -2.058 |
| ARPC4-TTLL3 | ARPC4-TTLL3 readthrough | -2.054 |
| EXOC2 | exocyst complex component 2 | -2.02665 |
| MAGEL2 | melanoma antigen family L2 | -2.02385 |
| SLITRK3 | SLIT and NTRK-like family, member 3 | -2.0234 |
| DNASE2 | deoxyribonuclease II, lysosomal | -2.01568 |
| KRTAP1-1 | keratin associated protein 1-1 | -2.01305 |
| CD44 | CD44 molecule (Indian blood group) | -2.00853 |
