CRCGN011_HEPG2_24H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 1.28 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

524 genes differentially expressed following the CRCGN011_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCH protein kinase C, eta 6.14895
MAMLD1 mastermind-like domain containing 1 5.8945
CAPN1 calpain 1, (mu/I) large subunit 5.6706
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 5.57685
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 5.36495
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.20665
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.087
MYLK myosin light chain kinase 5.06255
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.9671
STAP2 signal transducing adaptor family member 2 4.9589
TAC4 tachykinin 4 (hemokinin) 4.95855
PPARG peroxisome proliferator-activated receptor gamma 4.87515
TERT telomerase reverse transcriptase 4.86805
PARP1 poly (ADP-ribose) polymerase 1 4.79025
ANO1 anoctamin 1, calcium activated chloride channel 4.67795
CSK c-src tyrosine kinase 4.66275
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.5015
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 4.4816
C2CD2 C2 calcium-dependent domain containing 2 4.38615
CCNA1 cyclin A1 4.31755
MSRA methionine sulfoxide reductase A 4.3097
TIMP2 TIMP metallopeptidase inhibitor 2 4.1193
IDE insulin-degrading enzyme 4.0618
DUSP4 dual specificity phosphatase 4 4.05647
MOK MOK protein kinase 4.00305
ADAT1 adenosine deaminase, tRNA-specific 1 3.9669
COL4A1 collagen, type IV, alpha 1 3.90745
RRAGA Ras-related GTP binding A 3.9025
HOXA10 homeobox A10 3.90112
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 3.818
TRIM13 tripartite motif containing 13 3.791
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.7815
MAN2B1 mannosidase, alpha, class 2B, member 1 3.7801
LAGE3 L antigen family, member 3 3.77995
OXCT1 3-oxoacid CoA transferase 1 3.7666
MEST mesoderm specific transcript 3.7029
PRAF2 PRA1 domain family, member 2 3.68205
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 3.67982
BACE2 beta-site APP-cleaving enzyme 2 3.6677
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.54335
DNM1 dynamin 1 3.54235
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.4936
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 3.47475
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.44212
SUMO4 small ubiquitin-like modifier 4 3.39465
RUNX3 runt-related transcription factor 3 3.38357
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.35075
HOOK2 hook microtubule-tethering protein 2 3.29575
E2F2 E2F transcription factor 2 3.29275
DUSP10 dual specificity phosphatase 10 3.2861
NENF neudesin neurotrophic factor 3.23665
TCHH trichohyalin 3.2288
PSG5 pregnancy specific beta-1-glycoprotein 5 3.2259
LPAR2 lysophosphatidic acid receptor 2 3.21697
CTSL cathepsin L 3.2012
ABHD4 abhydrolase domain containing 4 3.1657
IL36RN interleukin 36 receptor antagonist 3.14545
KAT6A K(lysine) acetyltransferase 6A 3.09617
BCL2 B-cell CLL/lymphoma 2 3.09043
COG4 component of oligomeric golgi complex 4 3.09
CASC3 cancer susceptibility candidate 3 3.085
IGFBP3 insulin-like growth factor binding protein 3 3.01027
PSG6 pregnancy specific beta-1-glycoprotein 6 3.00257
KRT34 keratin 34, type I 3.00245
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.9994
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.9726
DCAF13 DDB1 and CUL4 associated factor 13 2.9696
COL4A2 collagen, type IV, alpha 2 2.96357
PSG2 pregnancy specific beta-1-glycoprotein 2 2.95645
RPAP1 RNA polymerase II associated protein 1 2.93065
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.91728
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.8773
IL12A interleukin 12A 2.8737
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.8543
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.84025
MCOLN1 mucolipin 1 2.8373
MBD5 methyl-CpG binding domain protein 5 2.81455
MYOZ3 myozenin 3 2.8104
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.80935
DDR1 discoidin domain receptor tyrosine kinase 1 2.78355
NT5DC2 5'-nucleotidase domain containing 2 2.78255
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.7698
SCRN1 secernin 1 2.76515
INSIG1 insulin induced gene 1 2.76337
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.76105
METTL16 methyltransferase like 16 2.75995
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.7561
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.75455
CCDC86 coiled-coil domain containing 86 2.7374
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.73025
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.7278
POPDC3 popeye domain containing 3 2.69865
SCARB1 scavenger receptor class B, member 1 2.69855
SOCS2 suppressor of cytokine signaling 2 2.69462
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.69117
FBL fibrillarin 2.68225
SNAP25 synaptosomal-associated protein, 25kDa 2.68182
CRTAP cartilage associated protein 2.68155
PRDM13 PR domain containing 13 2.6808
UBE2A ubiquitin-conjugating enzyme E2A 2.68008
ARL17B ADP-ribosylation factor-like 17B 2.67205
STK10 serine/threonine kinase 10 2.6597
CXCR4 chemokine (C-X-C motif) receptor 4 2.65722
F8A2 coagulation factor VIII-associated 2 2.65435
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 2.64885
ZFY zinc finger protein, Y-linked 2.63705
CUL1 cullin 1 2.6359
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.6295
MAN2A1 mannosidase, alpha, class 2A, member 1 2.6294
CAPN6 calpain 6 2.62593
STRADA STE20-related kinase adaptor alpha 2.62577
KRT75 keratin 75, type II 2.6241
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.61895
CHMP6 charged multivesicular body protein 6 2.6189
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 2.6143
HMG20B high mobility group 20B 2.60488
CDKN2A cyclin-dependent kinase inhibitor 2A 2.5951
SP4 Sp4 transcription factor 2.57635
ANKRD10 ankyrin repeat domain 10 2.5704
ALDOC aldolase C, fructose-bisphosphate 2.56835
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.5598
COLEC10 collectin sub-family member 10 (C-type lectin) 2.5576
USP6 ubiquitin specific peptidase 6 2.5541
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.5526
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.5359
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2.5233
NFIL3 nuclear factor, interleukin 3 regulated 2.51535
BATF basic leucine zipper transcription factor, ATF-like 2.51365
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.5082
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.5062
NOSIP nitric oxide synthase interacting protein 2.4902
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.4781
UBE3C ubiquitin protein ligase E3C 2.47295
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.4701
TRAPPC3 trafficking protein particle complex 3 2.46465
ATP13A1 ATPase type 13A1 2.4593
SEC24C SEC24 family member C 2.45415
TMEM214 transmembrane protein 214 2.4464
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.44595
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.44515
ZNF282 zinc finger protein 282 2.42855
APH1B APH1B gamma secretase subunit 2.4274
TRIM16 tripartite motif containing 16 2.42555
FAM20B family with sequence similarity 20, member B 2.42502
SRCAP Snf2-related CREBBP activator protein 2.42382
PSG4 pregnancy specific beta-1-glycoprotein 4 2.42115
SH2D4A SH2 domain containing 4A 2.42045
CYTH3 cytohesin 3 2.41645
KDM5D lysine (K)-specific demethylase 5D 2.40985
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.4074
PDLIM1 PDZ and LIM domain 1 2.4073
FGF7 fibroblast growth factor 7 2.403
MEN1 multiple endocrine neoplasia I 2.39955
TRAP1 TNF receptor-associated protein 1 2.39545
FASTK Fas-activated serine/threonine kinase 2.38602
HOXA2 homeobox A2 2.38135
MRM3 mitochondrial rRNA methyltransferase 3 2.3807
CEP152 centrosomal protein 152kDa 2.37565
LMAN1 lectin, mannose-binding, 1 2.37542
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.3736
TRIM49D2 tripartite motif containing 49D2 2.3693
WBP2 WW domain binding protein 2 2.369
TGFB3 transforming growth factor, beta 3 2.3644
PRR14L proline rich 14-like 2.3588
NLGN4Y neuroligin 4, Y-linked 2.3493
PM20D1 peptidase M20 domain containing 1 2.34562
SNRPA small nuclear ribonucleoprotein polypeptide A 2.3453
BTK Bruton agammaglobulinemia tyrosine kinase 2.3445
KRTAP2-3 keratin associated protein 2-3 2.3379
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.33537
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.3332
MAGEA9B melanoma antigen family A9B 2.3188
SETD5 SET domain containing 5 2.3129
EIF4A3 eukaryotic translation initiation factor 4A3 2.3118
TTC1 tetratricopeptide repeat domain 1 2.30705
USP11 ubiquitin specific peptidase 11 2.30565
GLI2 GLI family zinc finger 2 2.3047
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.30275
LZTR1 leucine-zipper-like transcription regulator 1 2.299
AMDHD2 amidohydrolase domain containing 2 2.299
WDR83OS WD repeat domain 83 opposite strand 2.29115
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.29105
TMEM134 transmembrane protein 134 2.28785
FOXO3 forkhead box O3 2.28754
POLR1A polymerase (RNA) I polypeptide A, 194kDa 2.28485
SMYD3 SET and MYND domain containing 3 2.28405
FPGS folylpolyglutamate synthase 2.28375
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.2822
USP9Y ubiquitin specific peptidase 9, Y-linked 2.28073
HELZ helicase with zinc finger 2.2778
COL7A1 collagen, type VII, alpha 1 2.27597
PRKCD protein kinase C, delta 2.27385
CPNE2 copine II 2.2653
CD53 CD53 molecule 2.26325
OSMR oncostatin M receptor 2.26185
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.255
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.25422
SATB1 SATB homeobox 1 2.2497
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.2488
PRSS23 protease, serine, 23 2.24435
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.242
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 2.2361
LECT2 leukocyte cell-derived chemotaxin 2 2.23235
SGSM3 small G protein signaling modulator 3 2.23108
MYBBP1A MYB binding protein (P160) 1a 2.23065
BDNF brain-derived neurotrophic factor 2.22415
OSGIN1 oxidative stress induced growth inhibitor 1 2.2153
ANKRD26 ankyrin repeat domain 26 2.2084
SH3PXD2A SH3 and PX domains 2A 2.20727
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.2059
HOXC11 homeobox C11 2.1962
IFNA13 interferon, alpha 13 2.18645
RRH retinal pigment epithelium-derived rhodopsin homolog 2.18045
PLA2G3 phospholipase A2, group III 2.1793
EFCAB14 EF-hand calcium binding domain 14 2.17784
HOPX HOP homeobox 2.1756
FXYD5 FXYD domain containing ion transport regulator 5 2.1685
DUSP14 dual specificity phosphatase 14 2.1668
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.1658
MFAP3L microfibrillar-associated protein 3-like 2.15531
N4BP3 NEDD4 binding protein 3 2.15505
ZBTB40 zinc finger and BTB domain containing 40 2.15235
MKS1 Meckel syndrome, type 1 2.15195
LAG3 lymphocyte-activation gene 3 2.1455
CDK6 cyclin-dependent kinase 6 2.13995
CLDN15 claudin 15 2.13985
LOC100996709 ADP-ribosylation factor-like protein 17 2.13702
NMT2 N-myristoyltransferase 2 2.13263
IKZF2 IKAROS family zinc finger 2 (Helios) 2.1325
NCF4 neutrophil cytosolic factor 4, 40kDa 2.13245
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.13225
TUBGCP4 tubulin, gamma complex associated protein 4 2.1293
MYOZ1 myozenin 1 2.12655
AADAC arylacetamide deacetylase 2.12325
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.12112
SRPX sushi-repeat containing protein, X-linked 2.11775
CTF1 cardiotrophin 1 2.11195
FOSL1 FOS-like antigen 1 2.1111
KRT24 keratin 24, type I 2.1086
NNT nicotinamide nucleotide transhydrogenase 2.10675
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.104
SNAP29 synaptosomal-associated protein, 29kDa 2.10355
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 2.1026
PRKCE protein kinase C, epsilon 2.10185
NUP43 nucleoporin 43kDa 2.101
ERBIN erbb2 interacting protein 2.0971
UNC5C unc-5 homolog C (C. elegans) 2.09535
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.09532
MDN1 MDN1, midasin homolog (yeast) 2.0946
ADAM18 ADAM metallopeptidase domain 18 2.0927
VPS35L VPS35 endosomal protein sorting factor like 2.0877
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.0858
SPPL2A signal peptide peptidase like 2A 2.08535
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.0826
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) 2.0825
BAAT bile acid CoA:amino acid N-acyltransferase 2.08235
COMMD3-BMI1 COMMD3-BMI1 readthrough 2.07875
NOP10 NOP10 ribonucleoprotein 2.07775
CCSER2 coiled-coil serine-rich protein 2 2.07565
PDE5A phosphodiesterase 5A, cGMP-specific 2.0695
NKG7 natural killer cell granule protein 7 2.06405
ATF7IP2 activating transcription factor 7 interacting protein 2 2.0633
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.06225
GML glycosylphosphatidylinositol anchored molecule like 2.05935
GZMK granzyme K (granzyme 3; tryptase II) 2.05855
IL36G interleukin 36, gamma 2.05835
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.05715
GPR18 G protein-coupled receptor 18 2.05185
LIMD1 LIM domains containing 1 2.04915
COL6A3 collagen, type VI, alpha 3 2.04665
ENTREP3 endosomal transmembrane epsin interactor 3 2.04598
SCD5 stearoyl-CoA desaturase 5 2.0448
KLHL4 kelch-like family member 4 2.04465
GPR171 G protein-coupled receptor 171 2.0435
SIPA1 signal-induced proliferation-associated 1 2.04325
CST7 cystatin F (leukocystatin) 2.04275
MEF2C myocyte enhancer factor 2C 2.04138
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.04095
CDK7 cyclin-dependent kinase 7 2.0387
ZNF280B zinc finger protein 280B 2.03745
NRN1 neuritin 1 2.03715
CTSW cathepsin W 2.037
PEX11A peroxisomal biogenesis factor 11 alpha 2.03475
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.0317
RNFT1 ring finger protein, transmembrane 1 2.03078
VASH2 vasohibin 2 2.03035
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.03005
PRR3 proline rich 3 2.029
ENOSF1 enolase superfamily member 1 2.02875
SGPP2 sphingosine-1-phosphate phosphatase 2 2.0276
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 2.0266
OTC ornithine carbamoyltransferase 2.0265
NIT1 nitrilase 1 2.02595
ZNF692 zinc finger protein 692 2.0252
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.02205
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.0213
TUBA3C tubulin, alpha 3c 2.0207
FXR2 fragile X mental retardation, autosomal homolog 2 2.01868
TOP2A topoisomerase (DNA) II alpha 170kDa 2.01842
NANOS3 nanos homolog 3 (Drosophila) 2.0173
LPIN2 lipin 2 2.01678
TARBP1 TAR (HIV-1) RNA binding protein 1 2.0132
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.0126
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.01035
ELSPBP1 epididymal sperm binding protein 1 2.00795
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.00705
CHRM2 cholinergic receptor, muscarinic 2 2.00395
FAT4 FAT atypical cadherin 4 2.00315
FBXL7 F-box and leucine-rich repeat protein 7 2.00175

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -10.0
VAT1 vesicle amine transport 1 -8.24945
CDC20 cell division cycle 20 -6.1223
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -5.83015
FBXL12 F-box and leucine-rich repeat protein 12 -5.80425
ISOC1 isochorismatase domain containing 1 -5.63905
KDM3A lysine (K)-specific demethylase 3A -5.61895
FAIM Fas apoptotic inhibitory molecule -5.54145
TSEN2 TSEN2 tRNA splicing endonuclease subunit -5.33345
ACOT9 acyl-CoA thioesterase 9 -5.3293
ZW10 zw10 kinetochore protein -5.27975
FASTKD5 FAST kinase domains 5 -5.2278
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.1824
DSG2 desmoglein 2 -5.1737
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -5.0672
ARID5B AT rich interactive domain 5B (MRF1-like) -4.986
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.9815
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -4.94455
CCNB2 cyclin B2 -4.923
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.8831
HAT1 histone acetyltransferase 1 -4.8275
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.82685
USP6NL USP6 N-terminal like -4.81635
DUSP6 dual specificity phosphatase 6 -4.78213
NCK1 NCK adaptor protein 1 -4.73997
FABP5 fatty acid binding protein 5 (psoriasis-associated) -4.6705
TCTN1 tectonic family member 1 -4.6365
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.49785
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -4.46305
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.4143
DNM1L dynamin 1-like -4.3936
RFC2 replication factor C (activator 1) 2, 40kDa -4.33562
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -4.2946
PPP1R13B protein phosphatase 1, regulatory subunit 13B -4.2572
ANO10 anoctamin 10 -4.1833
SCAND1 SCAN domain containing 1 -4.15495
TOR1A torsin family 1, member A (torsin A) -4.15425
MAPK13 mitogen-activated protein kinase 13 -4.05445
PECR peroxisomal trans-2-enoyl-CoA reductase -3.99635
ACAA1 acetyl-CoA acyltransferase 1 -3.91785
NUP93 nucleoporin 93kDa -3.89345
ZNF586 zinc finger protein 586 -3.66675
STAMBP STAM binding protein -3.60065
STXBP2 syntaxin binding protein 2 -3.56275
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -3.53485
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.53165
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.5035
CD58 CD58 molecule -3.49178
SNX7 sorting nexin 7 -3.36615
TEX10 testis expressed 10 -3.33365
AGTPBP1 ATP/GTP binding protein 1 -3.31865
MAP2K5 mitogen-activated protein kinase kinase 5 -3.29927
EAPP E2F-associated phosphoprotein -3.239
SINHCAF SIN3-HDAC complex associated factor -3.20285
NR1H2 nuclear receptor subfamily 1, group H, member 2 -3.1742
ENOPH1 enolase-phosphatase 1 -3.1413
RAI14 retinoic acid induced 14 -3.1346
RNF38 ring finger protein 38 -3.13185
GMEB2 glucocorticoid modulatory element binding protein 2 -3.03795
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -3.01905
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -3.01635
HEATR1 HEAT repeat containing 1 -2.98513
ZFAND1 zinc finger, AN1-type domain 1 -2.94645
CAB39 calcium binding protein 39 -2.92225
CRYZ crystallin, zeta (quinone reductase) -2.9151
IFRD2 interferon-related developmental regulator 2 -2.89132
HSPA1A heat shock 70kDa protein 1A -2.84435
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.80757
GOLT1B golgi transport 1B -2.80045
GLB1L2 galactosidase, beta 1-like 2 -2.7993
UBAC1 UBA domain containing 1 -2.7985
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.77945
SDCBP syndecan binding protein (syntenin) -2.76085
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.74887
LOXL1 lysyl oxidase-like 1 -2.7459
TESK1 testis-specific kinase 1 -2.72805
AZIN1 antizyme inhibitor 1 -2.70653
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.68415
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.6819
FOS FBJ murine osteosarcoma viral oncogene homolog -2.65915
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.6522
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.6471
ZNF7 zinc finger protein 7 -2.627
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.61225
EMC9 ER membrane protein complex subunit 9 -2.60235
SRFBP1 serum response factor binding protein 1 -2.5908
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.5839
SGCE sarcoglycan, epsilon -2.5802
CDK4 cyclin-dependent kinase 4 -2.57855
PRPF38B pre-mRNA processing factor 38B -2.57437
RBBP8 retinoblastoma binding protein 8 -2.56805
RIOK3 RIO kinase 3 -2.55413
FCHO1 FCH domain only 1 -2.5463
SLC35F2 solute carrier family 35, member F2 -2.539
SDC4 syndecan 4 -2.5387
ZC3H15 zinc finger CCCH-type containing 15 -2.53455
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.53175
PRPF4 pre-mRNA processing factor 4 -2.52093
OSBPL11 oxysterol binding protein-like 11 -2.51135
AKAP8 A kinase (PRKA) anchor protein 8 -2.51043
UNC119B unc-119 homolog B (C. elegans) -2.5078
PEG10 paternally expressed 10 -2.5
CAPRIN2 caprin family member 2 -2.4935
TM9SF3 transmembrane 9 superfamily member 3 -2.4817
ZBTB10 zinc finger and BTB domain containing 10 -2.47655
DCAF15 DDB1 and CUL4 associated factor 15 -2.47143
ZBED2 zinc finger, BED-type containing 2 -2.45185
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.4485
MELK maternal embryonic leucine zipper kinase -2.4205
LEMD3 LEM domain containing 3 -2.41185
HOOK3 hook microtubule-tethering protein 3 -2.3976
ANXA1 annexin A1 -2.39595
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.38905
STAT1 signal transducer and activator of transcription 1, 91kDa -2.36795
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.36645
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.36325
TTF1 transcription termination factor, RNA polymerase I -2.35063
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.3469
RAB5B RAB5B, member RAS oncogene family -2.3391
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.3369
TMEM165 transmembrane protein 165 -2.332
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.3302
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.32845
ZNF8 zinc finger protein 8 -2.3236
SNX4 sorting nexin 4 -2.32185
KLF10 Kruppel-like factor 10 -2.32165
LY75-CD302 LY75-CD302 readthrough -2.3048
SARAF store-operated calcium entry-associated regulatory factor -2.30435
ZNF304 zinc finger protein 304 -2.3012
XPA xeroderma pigmentosum, complementation group A -2.3008
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 -2.2883
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.274
CORO1C coronin, actin binding protein, 1C -2.26825
CIRBP cold inducible RNA binding protein -2.26347
FAM168B family with sequence similarity 168, member B -2.26185
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.25942
TOR1B torsin family 1, member B (torsin B) -2.25555
TBPL1 TBP-like 1 -2.25305
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.2451
RYK receptor-like tyrosine kinase -2.24167
OGDHL oxoglutarate dehydrogenase-like -2.23425
MXD1 MAX dimerization protein 1 -2.23275
SESN1 sestrin 1 -2.23255
USP22 ubiquitin specific peptidase 22 -2.23158
PNPLA4 patatin-like phospholipase domain containing 4 -2.22612
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.22325
PBX3 pre-B-cell leukemia homeobox 3 -2.2223
THAP4 THAP domain containing 4 -2.214
DENND2D DENN/MADD domain containing 2D -2.20295
CAVIN3 caveolae associated protein 3 -2.1865
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.1823
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.17885
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.17745
ZNF562 zinc finger protein 562 -2.1751
IMMT inner membrane protein, mitochondrial -2.175
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.17225
RTN3 reticulon 3 -2.16825
NUAK2 NUAK family, SNF1-like kinase, 2 -2.1674
PELI2 pellino E3 ubiquitin protein ligase family member 2 -2.16515
ZNF16 zinc finger protein 16 -2.16385
NPDC1 neural proliferation, differentiation and control, 1 -2.1588
ZC2HC1A zinc finger, C2HC-type containing 1A -2.1574
REEP5 receptor accessory protein 5 -2.15685
RESF1 retroelement silencing factor 1 -2.1464
SURF2 surfeit 2 -2.1435
MUTYH mutY homolog -2.14145
TOB1 transducer of ERBB2, 1 -2.13835
MAPK12 mitogen-activated protein kinase 12 -2.1239
CHEK1 checkpoint kinase 1 -2.11775
ABHD10 abhydrolase domain containing 10 -2.11755
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.1175
FBXL6 F-box and leucine-rich repeat protein 6 -2.11355
ZC3H7A zinc finger CCCH-type containing 7A -2.11195
RAI2 retinoic acid induced 2 -2.11085
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.11045
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.10815
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.1037
GREM1 gremlin 1, DAN family BMP antagonist -2.09998
GRN granulin -2.09975
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.098
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -2.09687
ZNF669 zinc finger protein 669 -2.0895
DOCK4 dedicator of cytokinesis 4 -2.0842
SLC35A5 solute carrier family 35, member A5 -2.08305
SEH1L SEH1-like (S. cerevisiae) -2.07855
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -2.07655
SERINC1 serine incorporator 1 -2.0732
CREBL2 cAMP responsive element binding protein-like 2 -2.07275
GMFB glia maturation factor, beta -2.0645
HTRA1 HtrA serine peptidase 1 -2.05075
HCCS holocytochrome c synthase -2.04777
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.0446
ACOT8 acyl-CoA thioesterase 8 -2.03785
ANXA7 annexin A7 -2.03665
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -2.0364
ERP44 endoplasmic reticulum protein 44 -2.0307
FER fer (fps/fes related) tyrosine kinase -2.0307
INAVA innate immunity activator -2.0304
ATF5 activating transcription factor 5 -2.02907
PAIP2B poly(A) binding protein interacting protein 2B -2.02815
CCL14 chemokine (C-C motif) ligand 14 -2.02635
LOC127933115 uncharacterized LOC127933115 -2.02255
PKP2 plakophilin 2 -2.02005
TM7SF3 transmembrane 7 superfamily member 3 -2.01915
TM9SF2 transmembrane 9 superfamily member 2 -2.01915
ITGAV integrin, alpha V -2.01885
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.01813
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -2.01605
PALM paralemmin -2.01135
BRD3 bromodomain containing 3 -2.00957
SOAT2 sterol O-acyltransferase 2 -2.00842
FUBP3 far upstream element (FUSE) binding protein 3 -2.0073
TCEAL2 transcription elongation factor A (SII)-like 2 -2.00645
NEK11 NIMA-related kinase 11 -2.0041