| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | m-phenylenediamine.2hcl 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN011_HEPG2_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.76495 |
| UBQLN2 | ubiquilin 2 | 5.38425 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.35145 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.1022 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.9638 |
| LCN2 | lipocalin 2 | 4.93455 |
| PRR15L | proline rich 15-like | 4.79835 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.34125 |
| GATA3 | GATA binding protein 3 | 3.9803 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.8291 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 3.78125 |
| CHMP6 | charged multivesicular body protein 6 | 3.7313 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.55805 |
| CHN1 | chimerin 1 | 3.24045 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.91118 |
| TRAM2 | translocation associated membrane protein 2 | 2.74182 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.70335 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.68423 |
| CTSL | cathepsin L | 2.5756 |
| VGLL4 | vestigial-like family member 4 | 2.57215 |
| RAB31 | RAB31, member RAS oncogene family | 2.48955 |
| GPATCH8 | G patch domain containing 8 | 2.46285 |
| DIPK1A | divergent protein kinase domain 1A | 2.4069 |
| ZNF318 | zinc finger protein 318 | 2.4023 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.3495 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.32307 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.31545 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.24405 |
| SCG2 | secretogranin II | 2.22185 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 2.2174 |
| TRIM13 | tripartite motif containing 13 | 2.21515 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.20185 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.16105 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 2.0583 |
| MEIS2 | Meis homeobox 2 | 2.05075 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.04365 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.0431 |
| EDN1 | endothelin 1 | 2.0399 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 2.0337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -5.6669 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.9329 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.8087 |
| NGRN | neugrin, neurite outgrowth associated | -4.2402 |
| SPAG4 | sperm associated antigen 4 | -4.2109 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.19035 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -4.18528 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -4.0749 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.8771 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.46825 |
| ADI1 | acireductone dioxygenase 1 | -3.3085 |
| PCNA | proliferating cell nuclear antigen | -3.0229 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -2.70882 |
| XPO7 | exportin 7 | -2.43567 |
| RAD51C | RAD51 paralog C | -2.33008 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.31185 |
| GOLT1B | golgi transport 1B | -2.31155 |
| STX8 | syntaxin 8 | -2.21905 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -2.21725 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.21065 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -2.1841 |
| HEATR1 | HEAT repeat containing 1 | -2.12117 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | -2.1135 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -2.0959 |
| ZNF586 | zinc finger protein 586 | -2.0729 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -2.07035 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.05675 |
| FAT1 | FAT atypical cadherin 1 | -2.0348 |
| RBBP9 | retinoblastoma binding protein 9 | -2.02575 |
| IL18RAP | interleukin 18 receptor accessory protein | -2.0113 |
| NKG7 | natural killer cell granule protein 7 | -2.01095 |
