CRCGN011_HEPG2_24H:A18 Gene Set
Genes
51 genes differentially expressed following the CRCGN011_HEPG2_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
5.1477
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.1161
|
|
MYLK
|
myosin light chain kinase
|
5.035
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
HOXA10
|
homeobox A10
|
4.40028
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.2709
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.25688
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.15629
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.0829
|
|
TLR4
|
toll-like receptor 4
|
3.82335
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.79915
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.6528
|
|
EPHA3
|
EPH receptor A3
|
3.52782
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
3.31425
|
|
CCNF
|
cyclin F
|
3.1618
|
|
COQ8A
|
coenzyme Q8A
|
3.03405
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.46155
|
|
EVL
|
Enah/Vasp-like
|
2.4388
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.4141
|
|
NMU
|
neuromedin U
|
2.28545
|
|
LRIG2
|
leucine-rich repeats and immunoglobulin-like domains 2
|
2.2735
|
|
ELAC2
|
elaC ribonuclease Z 2
|
2.1392
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.1349
|
|
FASTKD5
|
FAST kinase domains 5
|
2.0886
|
|
TMEM109
|
transmembrane protein 109
|
2.06075
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.05045
|
|
HELLS
|
helicase, lymphoid-specific
|
2.0395
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.41775
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-5.0
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.91645
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.82295
|
|
USP6NL
|
USP6 N-terminal like
|
-4.8212
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.09263
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.00735
|
|
PEG10
|
paternally expressed 10
|
-3.78238
|
|
CCNB2
|
cyclin B2
|
-3.77715
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.74723
|
|
TWF2
|
twinfilin actin binding protein 2
|
-3.6831
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.50245
|
|
GNAS
|
GNAS complex locus
|
-3.42279
|
|
HMG20B
|
high mobility group 20B
|
-3.32842
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.14975
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.7167
|
|
DDA1
|
DET1 and DDB1 associated 1
|
-2.5938
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.55005
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.46595
|
|
SENP6
|
SUMO1/sentrin specific peptidase 6
|
-2.1886
|
|
RNF167
|
ring finger protein 167
|
-2.16695
|
|
RAD51C
|
RAD51 paralog C
|
-2.10308
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-2.0363
|
