CRCGN011_HEPG2_24H:A21 Gene Set
Genes
45 genes differentially expressed following the CRCGN011_HEPG2_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MOK
|
MOK protein kinase
|
6.1889
|
|
CYCS
|
cytochrome c, somatic
|
5.85635
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
5.45815
|
|
STK10
|
serine/threonine kinase 10
|
5.09745
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.0
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.94835
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.4019
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.07505
|
|
GATA3
|
GATA binding protein 3
|
4.02028
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.80595
|
|
TLR4
|
toll-like receptor 4
|
3.42945
|
|
COL11A1
|
collagen, type XI, alpha 1
|
2.9916
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.97292
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.74475
|
|
MAGEA6
|
melanoma antigen family A6
|
2.62332
|
|
JADE2
|
jade family PHD finger 2
|
2.5683
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.44553
|
|
NME3
|
NME/NM23 nucleoside diphosphate kinase 3
|
2.4452
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.391
|
|
EVL
|
Enah/Vasp-like
|
2.36675
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.35344
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.34053
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.2789
|
|
RASSF1
|
Ras association (RalGDS/AF-6) domain family member 1
|
2.244
|
|
ZNF318
|
zinc finger protein 318
|
2.16545
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
2.11545
|
|
HAUS7
|
HAUS augmin-like complex, subunit 7
|
2.0669
|
|
NUDT1
|
nudix (nucleoside diphosphate linked moiety X)-type motif 1
|
2.06045
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.5754
|
|
GNAS
|
GNAS complex locus
|
-3.43779
|
|
TWF2
|
twinfilin actin binding protein 2
|
-3.2158
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.99145
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.8131
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.57942
|
|
SPAG4
|
sperm associated antigen 4
|
-2.579
|
|
STUM
|
stum, mechanosensory transduction mediator homolog
|
-2.31565
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.311
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.30932
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.28043
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.2505
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.20767
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.12735
|
|
TTLL7
|
tubulin tyrosine ligase-like family member 7
|
-2.1068
|
|
RNF167
|
ring finger protein 167
|
-2.06555
|
|
ACVR2A
|
activin A receptor, type IIA
|
-2.00795
|
