| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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101 genes differentially expressed following the CRCGN011_HEPG2_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | 5.8066 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.31885 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.927 |
| UBQLN2 | ubiquilin 2 | 4.7935 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.5591 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.53325 |
| NOTCH1 | notch 1 | 4.52285 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.34435 |
| TXNL4B | thioredoxin-like 4B | 3.8356 |
| IDE | insulin-degrading enzyme | 3.80288 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.64197 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.62895 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 3.61535 |
| HEBP1 | heme binding protein 1 | 3.5543 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.11853 |
| FASTKD5 | FAST kinase domains 5 | 3.0171 |
| PMM2 | phosphomannomutase 2 | 3.01335 |
| PIH1D1 | PIH1 domain containing 1 | 2.9904 |
| LOC122526780 | uncharacterized LOC122526780 | 2.96535 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.95335 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.86303 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.67113 |
| ATP11B | ATPase, class VI, type 11B | 2.64185 |
| TEFM | transcription elongation factor, mitochondrial | 2.4056 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B | 2.40155 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) | 2.35935 |
| HDAC4 | histone deacetylase 4 | 2.3472 |
| CCDC85C | coiled-coil domain containing 85C | 2.30885 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 2.29205 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.28115 |
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 2.2714 |
| CCNE2 | cyclin E2 | 2.24907 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.23395 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.2078 |
| EVL | Enah/Vasp-like | 2.17865 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 2.17455 |
| CYCS | cytochrome c, somatic | 2.17035 |
| VGLL4 | vestigial-like family member 4 | 2.15987 |
| KLHL2 | kelch-like family member 2 | 2.1418 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 2.13815 |
| SIRT3 | sirtuin 3 | 2.12022 |
| SYNGR2 | synaptogyrin 2 | 2.1195 |
| NECTIN3 | nectin cell adhesion molecule 3 | 2.0956 |
| FAM117A | family with sequence similarity 117, member A | 2.09125 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 2.06877 |
| PARG | poly (ADP-ribose) glycohydrolase | 2.0646 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 2.0613 |
| CBY1 | chibby homolog 1 (Drosophila) | 2.0503 |
| RGS18 | regulator of G-protein signaling 18 | 2.02015 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.00665 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.52974 |
| MAPK13 | mitogen-activated protein kinase 13 | -5.6473 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.2118 |
| TRIB3 | tribbles pseudokinase 3 | -5.1113 |
| PCNA | proliferating cell nuclear antigen | -3.5712 |
| TLCD3A | TLC domain containing 3A | -3.55925 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.53765 |
| ADI1 | acireductone dioxygenase 1 | -3.34345 |
| YME1L1 | YME1-like 1 ATPase | -3.26003 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.21695 |
| RNF167 | ring finger protein 167 | -2.91955 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.84715 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.60705 |
| NCR3 | natural cytotoxicity triggering receptor 3 | -2.38627 |
| CRYGB | crystallin, gamma B | -2.374 |
| LYPD3 | LY6/PLAUR domain containing 3 | -2.33775 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.3287 |
| LGMN | legumain | -2.32685 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -2.31165 |
| RBM34 | RNA binding motif protein 34 | -2.27185 |
| RPL37 | ribosomal protein L37 | -2.262 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | -2.2295 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -2.2256 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -2.20422 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | -2.1831 |
| NGRN | neugrin, neurite outgrowth associated | -2.1646 |
| UPK3B | uroplakin 3B | -2.16445 |
| WNT8B | wingless-type MMTV integration site family, member 8B | -2.15715 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.1454 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | -2.14223 |
| LEMD3 | LEM domain containing 3 | -2.13445 |
| PRR14L | proline rich 14-like | -2.1283 |
| FGF4 | fibroblast growth factor 4 | -2.12765 |
| AQP3 | aquaporin 3 (Gill blood group) | -2.12503 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.12165 |
| RPL6 | ribosomal protein L6 | -2.1201 |
| RPS12 | ribosomal protein S12 | -2.1194 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 | -2.11835 |
| RPLP1 | ribosomal protein, large, P1 | -2.11025 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.09823 |
| RPS13 | ribosomal protein S13 | -2.09765 |
| RPL38 | ribosomal protein L38 | -2.09525 |
| LOC102724428 | serine/threonine-protein kinase SIK1 | -2.0773 |
| PHF11 | PHD finger protein 11 | -2.0609 |
| RPL7A | ribosomal protein L7a | -2.05855 |
| PPT2 | palmitoyl-protein thioesterase 2 | -2.0554 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | -2.0429 |
| OPTN | optineurin | -2.0393 |
| UFC1 | ubiquitin-fold modifier conjugating enzyme 1 | -2.03835 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.03335 |
| PRODH2 | proline dehydrogenase (oxidase) 2 | -2.0224 |
