| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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89 genes differentially expressed following the CRCGN011_HEPG2_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.27985 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.28855 |
| MAP7 | microtubule-associated protein 7 | 4.7333 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.7223 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.51805 |
| UBQLN2 | ubiquilin 2 | 4.31435 |
| STIMATE | STIM activating enhancer | 4.1428 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.9248 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.2492 |
| FASTKD5 | FAST kinase domains 5 | 3.1102 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.7436 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.69465 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.6193 |
| GPATCH8 | G patch domain containing 8 | 2.43722 |
| CCNF | cyclin F | 2.42975 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 2.3961 |
| WNT4 | wingless-type MMTV integration site family, member 4 | 2.30325 |
| TMEM267 | transmembrane protein 267 | 2.29755 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 2.25697 |
| BAG1 | BCL2-associated athanogene | 2.24542 |
| ACYP2 | acylphosphatase 2, muscle type | 2.21365 |
| COQ8A | coenzyme Q8A | 2.21165 |
| ZKSCAN2 | zinc finger with KRAB and SCAN domains 2 | 2.19395 |
| DIPK1A | divergent protein kinase domain 1A | 2.17968 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | 2.14085 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | 2.13045 |
| ZNF668 | zinc finger protein 668 | 2.08385 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 2.06725 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.0629 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | 2.0573 |
| MX1 | MX dynamin-like GTPase 1 | 2.0511 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 2.04955 |
| FAM114A1 | family with sequence similarity 114, member A1 | 2.0429 |
| TRAPPC13 | trafficking protein particle complex 13 | 2.0426 |
| TSPYL4 | TSPY-like 4 | 2.03555 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.03053 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 2.0208 |
| TPD52L2 | tumor protein D52-like 2 | 2.02015 |
| VCP | valosin containing protein | 2.01695 |
| MED23 | mediator complex subunit 23 | 2.0165 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 2.01005 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 2.0025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| ADI1 | acireductone dioxygenase 1 | -5.2154 |
| CDC20 | cell division cycle 20 | -5.0 |
| TRIB3 | tribbles pseudokinase 3 | -4.77885 |
| PCNA | proliferating cell nuclear antigen | -4.7455 |
| CHMP4B | charged multivesicular body protein 4B | -4.72227 |
| CCNB2 | cyclin B2 | -4.67265 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.5581 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.5463 |
| DNM1L | dynamin 1-like | -4.2746 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.091 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.9639 |
| HAT1 | histone acetyltransferase 1 | -3.76055 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.69965 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.45395 |
| HEATR1 | HEAT repeat containing 1 | -3.37455 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.32405 |
| XPO7 | exportin 7 | -3.07382 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | -3.0651 |
| MTA1 | metastasis associated 1 | -2.82258 |
| CD58 | CD58 molecule | -2.81382 |
| DMTN | dematin actin binding protein | -2.651 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | -2.54925 |
| GYPB | glycophorin B (MNS blood group) | -2.53032 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.5115 |
| DSG2 | desmoglein 2 | -2.5077 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled | -2.4968 |
| ODR4 | odr-4 GPCR localization factor homolog | -2.4816 |
| TES | testin LIM domain protein | -2.45617 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -2.42698 |
| VASP | vasodilator-stimulated phosphoprotein | -2.31205 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -2.2949 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.25108 |
| SLC35E2B | solute carrier family 35, member E2B | -2.2181 |
| BEST1 | bestrophin 1 | -2.2033 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | -2.1927 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.17153 |
| NPC1 | Niemann-Pick disease, type C1 | -2.162 |
| EPB42 | erythrocyte membrane protein band 4.2 | -2.1546 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -2.1459 |
| CLK3 | CDC-like kinase 3 | -2.13365 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 | -2.13235 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -2.0686 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.05486 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -2.0499 |
| RIN1 | Ras and Rab interactor 1 | -2.00725 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | -2.00153 |
