| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN011_HEPG2_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 5.23585 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.2275 |
| GPATCH8 | G patch domain containing 8 | 5.2237 |
| ATP11B | ATPase, class VI, type 11B | 5.1115 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 5.00455 |
| CCDC92 | coiled-coil domain containing 92 | 4.81175 |
| STIMATE | STIM activating enhancer | 4.6724 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.63575 |
| EPN2 | epsin 2 | 4.4789 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.36442 |
| EPHB2 | EPH receptor B2 | 4.27306 |
| FZD7 | frizzled class receptor 7 | 4.17937 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.07005 |
| ABHD6 | abhydrolase domain containing 6 | 3.43808 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.3742 |
| FASTKD5 | FAST kinase domains 5 | 2.99325 |
| NOSIP | nitric oxide synthase interacting protein | 2.73445 |
| PRR15L | proline rich 15-like | 2.7101 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 2.6404 |
| CCNF | cyclin F | 2.49672 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 2.41645 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 2.36705 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.3543 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.32683 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | 2.31255 |
| PPA2 | pyrophosphatase (inorganic) 2 | 2.3001 |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 | 2.24305 |
| BAD | BCL2-associated agonist of cell death | 2.20735 |
| TCF12 | transcription factor 12 | 2.16975 |
| CREB1 | cAMP responsive element binding protein 1 | 2.16089 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 2.1584 |
| TRIT1 | tRNA isopentenyltransferase 1 | 2.1395 |
| TRAF1 | TNF receptor-associated factor 1 | 2.12095 |
| TRAPPC11 | trafficking protein particle complex 11 | 2.11315 |
| SMIM40 | small integral membrane protein 40 | 2.1033 |
| LAP3 | leucine aminopeptidase 3 | 2.09585 |
| BAX | BCL2-associated X protein | 2.0921 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 2.07325 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | 2.0303 |
| USP24 | ubiquitin specific peptidase 24 | 2.01517 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 2.00635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -5.45255 |
| CCNB1 | cyclin B1 | -4.9507 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.9119 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.8949 |
| TLCD3A | TLC domain containing 3A | -4.4391 |
| HAT1 | histone acetyltransferase 1 | -4.215 |
| WASHC4 | WASH complex subunit 4 | -3.69178 |
| GNAS | GNAS complex locus | -3.60928 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.42945 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.32785 |
| PCNA | proliferating cell nuclear antigen | -2.9513 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.9314 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.80948 |
| TUBA3C | tubulin, alpha 3c | -2.78045 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.67815 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.6607 |
| MTA1 | metastasis associated 1 | -2.52995 |
| TUBA3E | tubulin, alpha 3e | -2.52355 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.51907 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.5004 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.49805 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -2.4856 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -2.48345 |
| KDM8 | lysine (K)-specific demethylase 8 | -2.41945 |
| LALBA | lactalbumin, alpha- | -2.35185 |
| TOM1 | target of myb1 (chicken) | -2.3168 |
| NAGK | N-acetylglucosamine kinase | -2.3112 |
| DNASE2 | deoxyribonuclease II, lysosomal | -2.26038 |
| AMPD2 | adenosine monophosphate deaminase 2 | -2.2515 |
| SECTM1 | secreted and transmembrane 1 | -2.1983 |
| BZW2 | basic leucine zipper and W2 domains 2 | -2.19375 |
| RAB8A | RAB8A, member RAS oncogene family | -2.1656 |
| RNF167 | ring finger protein 167 | -2.14745 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.13955 |
| ADAM2 | ADAM metallopeptidase domain 2 | -2.11295 |
| MATK | megakaryocyte-associated tyrosine kinase | -2.1116 |
| CD82 | CD82 molecule | -2.09075 |
| CHMP1A | charged multivesicular body protein 1A | -2.02615 |
| PODNL1 | podocan-like 1 | -2.01 |
