| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dichlorophenol 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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60 genes differentially expressed following the CRCGN011_HEPG2_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.14275 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.71165 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.41325 |
| TLR4 | toll-like receptor 4 | 4.34065 |
| CCDC85B | coiled-coil domain containing 85B | 4.2444 |
| NMU | neuromedin U | 3.61155 |
| EVL | Enah/Vasp-like | 3.60175 |
| ZNF589 | zinc finger protein 589 | 3.43818 |
| PLSCR3 | phospholipid scramblase 3 | 3.30408 |
| CEP57 | centrosomal protein 57kDa | 3.21489 |
| MEST | mesoderm specific transcript | 3.1767 |
| COQ8A | coenzyme Q8A | 3.11625 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.79142 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.76172 |
| WASF3 | WAS protein family, member 3 | 2.53755 |
| FASTKD5 | FAST kinase domains 5 | 2.5044 |
| JADE2 | jade family PHD finger 2 | 2.42077 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.3512 |
| SLC35B1 | solute carrier family 35, member B1 | 2.32615 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.2383 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.1941 |
| DIPK1A | divergent protein kinase domain 1A | 2.17298 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 2.17205 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.14649 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.1459 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 2.1253 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.0958 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | 2.0771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.3859 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| LDHD | lactate dehydrogenase D | -5.0 |
| NUP85 | nucleoporin 85kDa | -4.72495 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.7102 |
| TLCD3A | TLC domain containing 3A | -4.59835 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.53455 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.36975 |
| ANKRD10 | ankyrin repeat domain 10 | -4.28595 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.7582 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.088 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.72578 |
| EVPL | envoplakin | -2.5917 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.4385 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.4222 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -2.32315 |
| SAP30BP | SAP30 binding protein | -2.2645 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.26447 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | -2.23705 |
| GPS1 | G protein pathway suppressor 1 | -2.23435 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.12985 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.11565 |
| PPOX | protoporphyrinogen oxidase | -2.10795 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.10695 |
| NPTXR | neuronal pentraxin receptor | -2.07805 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.06735 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -2.05795 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.04505 |
| NT5C | 5', 3'-nucleotidase, cytosolic | -2.0371 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | -2.01665 |
| PRPF3 | pre-mRNA processing factor 3 | -2.01165 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.0112 |