| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dichlorophenol 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN011_HEPG2_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 9.11515 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.20475 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 5.12455 |
| UBQLN2 | ubiquilin 2 | 5.12375 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.08655 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.76075 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.22855 |
| ADAM10 | ADAM metallopeptidase domain 10 | 4.13275 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.83815 |
| PRKCH | protein kinase C, eta | 3.58817 |
| FCHO1 | FCH domain only 1 | 3.5377 |
| DENND2D | DENN/MADD domain containing 2D | 3.4919 |
| TLR4 | toll-like receptor 4 | 3.344 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 3.19103 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.91795 |
| MAGEA6 | melanoma antigen family A6 | 2.91222 |
| CHN1 | chimerin 1 | 2.78575 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.68045 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.55735 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.54752 |
| PIH1D1 | PIH1 domain containing 1 | 2.5009 |
| FZD1 | frizzled class receptor 1 | 2.26682 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 2.2414 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 2.21935 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 2.2059 |
| KLHL9 | kelch-like family member 9 | 2.16307 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 2.1157 |
| CBR3 | carbonyl reductase 3 | 2.0895 |
| EXOC5 | exocyst complex component 5 | 2.05 |
| JADE2 | jade family PHD finger 2 | 2.02323 |
| PTOV1 | prostate tumor overexpressed 1 | 2.01345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.2109 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.53905 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -5.3567 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.19975 |
| LDHD | lactate dehydrogenase D | -5.1495 |
| CDC20 | cell division cycle 20 | -5.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.91645 |
| CCNB2 | cyclin B2 | -4.7597 |
| DUSP6 | dual specificity phosphatase 6 | -4.51875 |
| GDF15 | growth differentiation factor 15 | -4.28015 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.24295 |
| TLCD3A | TLC domain containing 3A | -3.75485 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.5196 |
| GNAS | GNAS complex locus | -3.45731 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.1548 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.5404 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.48055 |
| NGRN | neugrin, neurite outgrowth associated | -2.4757 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.41715 |
| MBIP | MAP3K12 binding inhibitory protein 1 | -2.23915 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.13275 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.102 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.03285 |
