CRCGN011_HEPG2_24H:B15 Gene Set
Genes
42 genes differentially expressed following the CRCGN011_HEPG2_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.86865
|
|
CBR3
|
carbonyl reductase 3
|
4.78285
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.58615
|
|
UBQLN2
|
ubiquilin 2
|
4.30025
|
|
HOXA10
|
homeobox A10
|
4.26892
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.24358
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.04425
|
|
EPN2
|
epsin 2
|
3.90075
|
|
TLR4
|
toll-like receptor 4
|
3.5453
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.26137
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.97697
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.93387
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.63028
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.6098
|
|
SLC44A1
|
solute carrier family 44 (choline transporter), member 1
|
2.43865
|
|
CCNF
|
cyclin F
|
2.37047
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.3378
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.14675
|
|
RAI14
|
retinoic acid induced 14
|
2.06225
|
|
SLC24A3
|
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
|
2.02803
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RPIA
|
ribose 5-phosphate isomerase A
|
-5.4457
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.96955
|
|
LDHD
|
lactate dehydrogenase D
|
-4.90895
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.8192
|
|
CDC20
|
cell division cycle 20
|
-4.66275
|
|
CD320
|
CD320 molecule
|
-4.5715
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.4227
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.19535
|
|
HMG20B
|
high mobility group 20B
|
-3.9394
|
|
PEG10
|
paternally expressed 10
|
-3.90547
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.62505
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.38185
|
|
CCNB2
|
cyclin B2
|
-3.2708
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.9351
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.64762
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.58024
|
|
ACO2
|
aconitase 2, mitochondrial
|
-2.57625
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.16465
|
|
DNAJC11
|
DnaJ (Hsp40) homolog, subfamily C, member 11
|
-2.1227
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.0872
|
|
MCM3
|
minichromosome maintenance complex component 3
|
-2.0802
|
|
CLPTM1
|
cleft lip and palate associated transmembrane protein 1
|
-2.00093
|
