| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | gemfibrozil 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN011_HEPG2_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 9.14995 |
| PRKCH | protein kinase C, eta | 7.40557 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.36165 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.21415 |
| UBQLN2 | ubiquilin 2 | 5.185 |
| CBR3 | carbonyl reductase 3 | 4.78285 |
| E2F2 | E2F transcription factor 2 | 4.75805 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.59085 |
| TLR4 | toll-like receptor 4 | 4.33505 |
| GATA3 | GATA binding protein 3 | 4.11395 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.76535 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.48368 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.05765 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.0243 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.968 |
| EPHA3 | EPH receptor A3 | 2.77418 |
| NOSIP | nitric oxide synthase interacting protein | 2.45135 |
| PKN1 | protein kinase N1 | 2.43397 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.40215 |
| CCNF | cyclin F | 2.39685 |
| PLA1A | phospholipase A1 member A | 2.185 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.12835 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.10405 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.08072 |
| CTC1 | CTS telomere maintenance complex component 1 | 2.0107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -5.0533 |
| LDHD | lactate dehydrogenase D | -4.94355 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.89525 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.88055 |
| VAT1 | vesicle amine transport 1 | -4.7964 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.4475 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.23145 |
| ZW10 | zw10 kinetochore protein | -4.06355 |
| EIF5 | eukaryotic translation initiation factor 5 | -4.04842 |
| GNAS | GNAS complex locus | -3.7002 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.58185 |
| VDAC1 | voltage-dependent anion channel 1 | -3.29268 |
| SNX11 | sorting nexin 11 | -2.80883 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.7881 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.59519 |
| CAPNS1 | calpain, small subunit 1 | -2.58625 |
| TMEM147 | transmembrane protein 147 | -2.5515 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.53555 |
| CD83 | CD83 molecule | -2.4291 |
| TBCB | tubulin folding cofactor B | -2.39978 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -2.35115 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | -2.2139 |
| PDCD5 | programmed cell death 5 | -2.18355 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -2.17715 |
| PGAM4 | phosphoglycerate mutase family member 4 | -2.10585 |
| ATF4 | activating transcription factor 4 | -2.0876 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | -2.08625 |
| USP21 | ubiquitin specific peptidase 21 | -2.0535 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -2.04336 |
| FHL2 | four and a half LIM domains 2 | -2.0429 |
