CRCGN011_HEPG2_24H:B22 Gene Set
Genes
56 genes differentially expressed following the CRCGN011_HEPG2_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
5.84955
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.46045
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.16115
|
|
TLR4
|
toll-like receptor 4
|
4.90695
|
|
UBQLN2
|
ubiquilin 2
|
4.84535
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.7202
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.6296
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.5428
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.23385
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.5403
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.7755
|
|
NOTCH1
|
notch 1
|
2.5519
|
|
PMM2
|
phosphomannomutase 2
|
2.4736
|
|
CCNF
|
cyclin F
|
2.39823
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.33067
|
|
NMU
|
neuromedin U
|
2.29125
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.29005
|
|
WDR7
|
WD repeat domain 7
|
2.26205
|
|
CTDP1
|
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
|
2.20685
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
2.1599
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.10637
|
|
EVL
|
Enah/Vasp-like
|
2.08795
|
|
JADE2
|
jade family PHD finger 2
|
2.08285
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.07032
|
|
KDM8
|
lysine (K)-specific demethylase 8
|
2.0669
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.0444
|
|
FBXL2
|
F-box and leucine-rich repeat protein 2
|
2.0292
|
|
MAGEA6
|
melanoma antigen family A6
|
2.02745
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
GOLT1B
|
golgi transport 1B
|
-5.66225
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.1069
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.04925
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.0
|
|
ZNF586
|
zinc finger protein 586
|
-4.96645
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.43875
|
|
MAP7
|
microtubule-associated protein 7
|
-4.35393
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-3.69655
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.6044
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.5855
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.4996
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.97135
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.91337
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.73645
|
|
CCNB2
|
cyclin B2
|
-2.6923
|
|
JPT2
|
Jupiter microtubule associated homolog 2
|
-2.40435
|
|
WASHC4
|
WASH complex subunit 4
|
-2.396
|
|
ZNF134
|
zinc finger protein 134
|
-2.36785
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.35613
|
|
LXN
|
latexin
|
-2.32105
|
|
FAT2
|
FAT atypical cadherin 2
|
-2.259
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.1831
|
|
S1PR5
|
sphingosine-1-phosphate receptor 5
|
-2.1528
|
|
MVP
|
major vault protein
|
-2.14905
|
|
IL18RAP
|
interleukin 18 receptor accessory protein
|
-2.13955
|
|
TVP23B
|
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
|
-2.02985
|
|
CENPE
|
centromere protein E, 312kDa
|
-2.01685
|
