| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | gemfibrozil 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
68 genes differentially expressed following the CRCGN011_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 5.88465 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.4506 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 5.37345 |
| TLR4 | toll-like receptor 4 | 4.8726 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.76735 |
| ZNF589 | zinc finger protein 589 | 4.48705 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.28925 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.88555 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.82993 |
| PLSCR1 | phospholipid scramblase 1 | 3.79975 |
| ATP11B | ATPase, class VI, type 11B | 3.6938 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.46318 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 3.36568 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.2656 |
| CHMP6 | charged multivesicular body protein 6 | 2.96445 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.8846 |
| SMAD3 | SMAD family member 3 | 2.87757 |
| FASTKD5 | FAST kinase domains 5 | 2.80145 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.32882 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.29015 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 2.22793 |
| RGS7 | regulator of G-protein signaling 7 | 2.2107 |
| RNLS | renalase, FAD-dependent amine oxidase | 2.2079 |
| DIPK1A | divergent protein kinase domain 1A | 2.18928 |
| SNX2 | sorting nexin 2 | 2.18528 |
| ARSJ | arylsulfatase family, member J | 2.14905 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.14905 |
| MAP1LC3C | microtubule-associated protein 1 light chain 3 gamma | 2.14695 |
| TSPAN6 | tetraspanin 6 | 2.13777 |
| COQ8A | coenzyme Q8A | 2.1278 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 2.1101 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 2.0763 |
| DNAH9 | dynein, axonemal, heavy chain 9 | 2.0762 |
| ATP4B | ATPase, H+/K+ exchanging, beta polypeptide | 2.0692 |
| EREG | epiregulin | 2.04755 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 2.03095 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 2.0192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLK1 | polo-like kinase 1 | -4.8319 |
| LOC124907782 | dual specificity protein phosphatase 22 | -4.45575 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.293 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.20585 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.90045 |
| ADI1 | acireductone dioxygenase 1 | -3.7625 |
| TWF2 | twinfilin actin binding protein 2 | -3.54395 |
| GNAS | GNAS complex locus | -3.39951 |
| PCNA | proliferating cell nuclear antigen | -3.17715 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.14125 |
| USP6NL | USP6 N-terminal like | -3.0541 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.85422 |
| TBCC | tubulin folding cofactor C | -2.6451 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.6337 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.5775 |
| RBM15B | RNA binding motif protein 15B | -2.4761 |
| DBN1 | drebrin 1 | -2.43318 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.4127 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.32595 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.3197 |
| UBFD1 | ubiquitin family domain containing 1 | -2.25535 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -2.21075 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.2004 |
| NVL | nuclear VCP-like | -2.19455 |
| CYTL1 | cytokine-like 1 | -2.1873 |
| GDF15 | growth differentiation factor 15 | -2.16865 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -2.1224 |
| H1-4 | H1.4 linker histone, cluster member | -2.08845 |
| WNT6 | wingless-type MMTV integration site family, member 6 | -2.07365 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -2.0241 |
| RNF25 | ring finger protein 25 | -2.02355 |
