| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethoxane 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN011_HEPG2_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.14875 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.92265 |
| LCN2 | lipocalin 2 | 4.79865 |
| IDE | insulin-degrading enzyme | 4.6938 |
| JADE2 | jade family PHD finger 2 | 4.54982 |
| SKIC2 | SKI2 subunit of superkiller complex | 4.49005 |
| MAP7 | microtubule-associated protein 7 | 4.28073 |
| MYLK | myosin light chain kinase | 4.2367 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 4.13335 |
| TLR4 | toll-like receptor 4 | 3.65645 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.4568 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.34068 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.21887 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.13365 |
| TGFB3 | transforming growth factor, beta 3 | 3.107 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.90555 |
| FASTKD5 | FAST kinase domains 5 | 2.7636 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | 2.7512 |
| SYNGR3 | synaptogyrin 3 | 2.516 |
| COQ8A | coenzyme Q8A | 2.41595 |
| CCNF | cyclin F | 2.39335 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) | 2.2778 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 2.27625 |
| CTNNBIP1 | catenin, beta interacting protein 1 | 2.23855 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.23265 |
| SYPL1 | synaptophysin-like 1 | 2.22182 |
| ZNF589 | zinc finger protein 589 | 2.21097 |
| MFN2 | mitofusin 2 | 2.12545 |
| TSPAN8 | tetraspanin 8 | 2.0849 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.07635 |
| FAM20B | family with sequence similarity 20, member B | 2.07295 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.07175 |
| CRYZ | crystallin, zeta (quinone reductase) | 2.033 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.00325 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NT5DC2 | 5'-nucleotidase domain containing 2 | -6.4107 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.9394 |
| HSPB1 | heat shock 27kDa protein 1 | -5.80635 |
| CCDC86 | coiled-coil domain containing 86 | -5.59205 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.87985 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.83835 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.587 |
| LDHD | lactate dehydrogenase D | -4.53685 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.3844 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.9683 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.8898 |
| TWF2 | twinfilin actin binding protein 2 | -3.447 |
| PCNA | proliferating cell nuclear antigen | -3.3888 |
| TRAP1 | TNF receptor-associated protein 1 | -3.3745 |
| GNAS | GNAS complex locus | -3.24066 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.2007 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.18495 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.82125 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.79229 |
| ACLY | ATP citrate lyase | -2.61497 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.5271 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -2.3778 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.37095 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.33135 |
| ZYX | zyxin | -2.208 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.2049 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.17605 |
| AMPD2 | adenosine monophosphate deaminase 2 | -2.1069 |
| YEATS2 | YEATS domain containing 2 | -2.0824 |
| CLIC3 | chloride intracellular channel 3 | -2.0732 |
| CCDC85B | coiled-coil domain containing 85B | -2.06125 |
| RTL8A | retrotransposon Gag like 8A | -2.0566 |
| LIME1 | Lck interacting transmembrane adaptor 1 | -2.0535 |
| TMEM243 | transmembrane protein 243, mitochondrial | -2.0359 |
| DERL2 | derlin 2 | -2.0339 |
