| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethoxane 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN011_HEPG2_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STIMATE | STIM activating enhancer | 10.0 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 10.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.0 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.71055 |
| UBQLN2 | ubiquilin 2 | 4.5246 |
| KLHL21 | kelch-like family member 21 | 4.5214 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 3.828 |
| CHMP6 | charged multivesicular body protein 6 | 3.7414 |
| PRR15L | proline rich 15-like | 3.59935 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.22815 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.92738 |
| GPATCH8 | G patch domain containing 8 | 2.84885 |
| CHEK2 | checkpoint kinase 2 | 2.83757 |
| FASTKD5 | FAST kinase domains 5 | 2.5695 |
| TFG | TRK-fused gene | 2.5364 |
| RNF167 | ring finger protein 167 | 2.4863 |
| HSPA14 | heat shock 70kDa protein 14 | 2.4632 |
| CYCS | cytochrome c, somatic | 2.3981 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 2.37905 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.37077 |
| SLC35G2 | solute carrier family 35, member G2 | 2.3623 |
| PTK2 | protein tyrosine kinase 2 | 2.28728 |
| DPF2 | D4, zinc and double PHD fingers family 2 | 2.26715 |
| FAM171A1 | family with sequence similarity 171, member A1 | 2.2637 |
| EPHA3 | EPH receptor A3 | 2.20212 |
| WFDC2 | WAP four-disulfide core domain 2 | 2.1839 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.12335 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 2.1227 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.09285 |
| TMEM59 | transmembrane protein 59 | 2.075 |
| NDST4 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 | 2.02455 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2.0186 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.99725 |
| THAP11 | THAP domain containing 11 | -4.66275 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.6254 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.53675 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.29605 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.26828 |
| FAIM | Fas apoptotic inhibitory molecule | -3.4866 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.39925 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.93827 |
| PCNA | proliferating cell nuclear antigen | -2.9 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.75397 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.57905 |
| DSG2 | desmoglein 2 | -2.49155 |
| KCTD3 | potassium channel tetramerization domain containing 3 | -2.47815 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.4006 |
| RANBP10 | RAN binding protein 10 | -2.3906 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -2.3904 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.2356 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.1996 |
| NT5M | 5',3'-nucleotidase, mitochondrial | -2.1507 |
| STAB1 | stabilin 1 | -2.01732 |
| KANK3 | KN motif and ankyrin repeat domains 3 | -2.0012 |
