CRCGN011_HEPG2_24H:C06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethoxane 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

53 genes differentially expressed following the CRCGN011_HEPG2_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 10.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.56055
LCN2 lipocalin 2 5.0
MYLK myosin light chain kinase 4.7125
RPP38 ribonuclease P/MRP 38kDa subunit 4.60875
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.57075
E2F2 E2F transcription factor 2 4.46915
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.0543
GPATCH8 G patch domain containing 8 4.01923
CXCL2 chemokine (C-X-C motif) ligand 2 3.95805
PRR15L proline rich 15-like 3.93365
GPER1 G protein-coupled estrogen receptor 1 3.66278
TIAM1 T-cell lymphoma invasion and metastasis 1 3.52367
MEST mesoderm specific transcript 2.89645
PLSCR3 phospholipid scramblase 3 2.87683
CCNF cyclin F 2.80125
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.7564
JADE2 jade family PHD finger 2 2.49948
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.4734
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.44185
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.21515
NT5DC2 5'-nucleotidase domain containing 2 2.1561
BTG3 BTG family, member 3 2.14955
KLHL9 kelch-like family member 9 2.07763
NMU neuromedin U 2.0709
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.01935
CCP110 centriolar coiled coil protein 110kDa 2.00205

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.95135
THAP11 THAP domain containing 11 -5.7278
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.3692
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.2073
GDF15 growth differentiation factor 15 -5.0
DSG2 desmoglein 2 -4.6654
WASHC4 WASH complex subunit 4 -3.42005
TOR1A torsin family 1, member A (torsin A) -3.2353
CLTC clathrin, heavy chain (Hc) -3.02025
PRCP prolylcarboxypeptidase (angiotensinase C) -2.6341
PRPF4 pre-mRNA processing factor 4 -2.63128
HMG20B high mobility group 20B -2.6203
TM9SF3 transmembrane 9 superfamily member 3 -2.60195
GRN granulin -2.53815
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -2.39605
SPAG4 sperm associated antigen 4 -2.3847
CCNB2 cyclin B2 -2.36415
MAPK13 mitogen-activated protein kinase 13 -2.35378
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.27335
FOS FBJ murine osteosarcoma viral oncogene homolog -2.25755
YME1L1 YME1-like 1 ATPase -2.14335
TMEM208 transmembrane protein 208 -2.14025
ACAA1 acetyl-CoA acyltransferase 1 -2.1327
XK X-linked Kx blood group -2.09295
SLC35F2 solute carrier family 35, member F2 -2.06695
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.00108