CRCGN011_HEPG2_24H:C08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caprolactam 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

467 genes differentially expressed following the CRCGN011_HEPG2_24H:C08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MOK MOK protein kinase 8.9031
TIAM1 T-cell lymphoma invasion and metastasis 1 7.5842
GSTZ1 glutathione S-transferase zeta 1 6.59405
E2F2 E2F transcription factor 2 6.2188
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.63615
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.63135
EPHB2 EPH receptor B2 5.43014
SATB1 SATB homeobox 1 5.39355
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.3565
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.31585
CCL2 chemokine (C-C motif) ligand 2 5.0369
ADRB2 adrenoceptor beta 2, surface 5.03165
LCN2 lipocalin 2 5.0
BACE2 beta-site APP-cleaving enzyme 2 4.9899
STIMATE STIM activating enhancer 4.8978
TREM1 triggering receptor expressed on myeloid cells 1 4.85395
PNKP polynucleotide kinase 3'-phosphatase 4.6418
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.57347
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 4.20132
ADGRE5 adhesion G protein-coupled receptor E5 4.19245
UBQLN2 ubiquilin 2 4.18425
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.9558
SSBP2 single-stranded DNA binding protein 2 3.6934
UNC5C unc-5 homolog C (C. elegans) 3.66815
EPM2AIP1 EPM2A (laforin) interacting protein 1 3.65
CHN1 chimerin 1 3.6051
OXCT1 3-oxoacid CoA transferase 1 3.5783
GPATCH8 G patch domain containing 8 3.55638
FAM163A family with sequence similarity 163, member A 3.5308
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.49395
CYCS cytochrome c, somatic 3.4287
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.3641
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.33197
CLDN9 claudin 9 3.30675
ZNF318 zinc finger protein 318 3.28412
ASB7 ankyrin repeat and SOCS box containing 7 3.138
ADAT1 adenosine deaminase, tRNA-specific 1 3.13115
SNX7 sorting nexin 7 3.1297
TUBA8 tubulin, alpha 8 3.12745
TAC4 tachykinin 4 (hemokinin) 3.105
PCDHB11 protocadherin beta 11 3.0986
AQP6 aquaporin 6, kidney specific 3.09787
DYNLT3 dynein, light chain, Tctex-type 3 3.08625
MIS12 MIS12 kinetochore complex component 3.02865
ADAM10 ADAM metallopeptidase domain 10 3.02183
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 3.02165
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.9923
ZBTB35 zinc finger and BTB domain containing 35 2.99195
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.98565
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.9832
ADPRH ADP-ribosylarginine hydrolase 2.9657
LMX1B LIM homeobox transcription factor 1, beta 2.9552
CELA2B chymotrypsin-like elastase family, member 2B 2.9401
SYT2 synaptotagmin II 2.91175
KIF5C kinesin family member 5C 2.9107
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.91
PRR3 proline rich 3 2.89585
VWA1 von Willebrand factor A domain containing 1 2.8674
LOC124908558 X antigen family member 1-like 2.86075
FEV FEV (ETS oncogene family) 2.85975
E2F1 E2F transcription factor 1 2.8492
HOXC8 homeobox C8 2.84505
OPRK1 opioid receptor, kappa 1 2.8328
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.8317
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.808
CGRRF1 cell growth regulator with ring finger domain 1 2.8029
MTA2 metastasis associated 1 family, member 2 2.80215
HYOU1 hypoxia up-regulated 1 2.79965
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.795
TGM5 transglutaminase 5 2.7783
PLAT plasminogen activator, tissue 2.77095
DCHS2 dachsous cadherin-related 2 2.7554
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.73103
CAPN1 calpain 1, (mu/I) large subunit 2.71125
CASR calcium-sensing receptor 2.6928
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 2.69125
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.66515
PRB2 proline-rich protein BstNI subfamily 2 2.6596
MYBPC3 myosin binding protein C, cardiac 2.64855
UNC5B unc-5 homolog B (C. elegans) 2.62702
CELA2A chymotrypsin-like elastase family, member 2A 2.61998
NMU neuromedin U 2.6157
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.61185
HOXD3 homeobox D3 2.59443
CD4 CD4 molecule 2.59175
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.59092
FZD2 frizzled class receptor 2 2.58905
CLTCL1 clathrin, heavy chain-like 1 2.58905
KIAA0513 KIAA0513 2.58635
GPER1 G protein-coupled estrogen receptor 1 2.58017
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.5787
COL4A1 collagen, type IV, alpha 1 2.57067
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.5648
THSD7A thrombospondin, type I, domain containing 7A 2.5584
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 2.5531
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.5489
FGF17 fibroblast growth factor 17 2.5477
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.54235
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2.54095
NKX2-8 NK2 homeobox 8 2.5299
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.52828
MMP1 matrix metallopeptidase 1 2.52798
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.5257
FANCC Fanconi anemia, complementation group C 2.523
GRIP2 glutamate receptor interacting protein 2 2.51695
CUZD1 CUB and zona pellucida-like domains 1 2.51665
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.50825
FKBP5 FK506 binding protein 5 2.50215
TSPYL5 TSPY-like 5 2.5008
ISL1 ISL LIM homeobox 1 2.4998
POM121L2 POM121 transmembrane nucleoporin-like 2 2.4954
IL13 interleukin 13 2.47385
LIN7A lin-7 homolog A (C. elegans) 2.4736
ZC2HC1C zinc finger, C2HC-type containing 1C 2.47325
HLA-DOA major histocompatibility complex, class II, DO alpha 2.47078
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.4695
CTRB2 chymotrypsinogen B2 2.46735
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.4671
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.45425
TH tyrosine hydroxylase 2.45075
MYH13 myosin, heavy chain 13, skeletal muscle 2.4494
ALX4 ALX homeobox 4 2.4441
SHISAL1 shisa like 1 2.44147
DRC4 dynein regulatory complex subunit 4 2.43865
SSX5 synovial sarcoma, X breakpoint 5 2.4356
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.4281
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.42429
PHOX2A paired-like homeobox 2a 2.42325
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.41415
STRA6 stimulated by retinoic acid 6 2.41365
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.4093
TLR2 toll-like receptor 2 2.40475
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.40275
PLK1 polo-like kinase 1 2.39985
THBD thrombomodulin 2.39717
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.39602
PID1 phosphotyrosine interaction domain containing 1 2.3901
DERL2 derlin 2 2.3862
KLF7 Kruppel-like factor 7 (ubiquitous) 2.38425
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.3802
MYH15 myosin, heavy chain 15 2.3745
PLD2 phospholipase D2 2.37425
CNTFR ciliary neurotrophic factor receptor 2.37085
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.36755
ACACB acetyl-CoA carboxylase beta 2.36625
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.36505
ZNF778 zinc finger protein 778 2.3645
ANO10 anoctamin 10 2.3618
DNAAF8 dynein axonemal assembly factor 8 2.3607
MC4R melanocortin 4 receptor 2.35755
RRAGA Ras-related GTP binding A 2.3574
SCAND1 SCAN domain containing 1 2.35125
THAP11 THAP domain containing 11 2.34885
CFAP74 cilia and flagella associated protein 74 2.3475
PRSS58 protease, serine, 58 2.34245
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.3403
SQOR sulfide quinone oxidoreductase 2.3393
KSR1 kinase suppressor of ras 1 2.33847
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.33655
LOC107987462 leukocyte immunoglobulin-like receptor subfamily B member 3 2.33496
GRM4 glutamate receptor, metabotropic 4 2.3343
SLC35F6 solute carrier family 35, member F6 2.334
GJA3 gap junction protein, alpha 3, 46kDa 2.325
CRLF2 cytokine receptor-like factor 2 2.3237
JADE2 jade family PHD finger 2 2.32153
PARP1 poly (ADP-ribose) polymerase 1 2.3212
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.32095
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 2.3192
TLR5 toll-like receptor 5 2.31845
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.3124
MORN1 MORN repeat containing 1 2.30785
GPR162 G protein-coupled receptor 162 2.30655
TBL1Y transducin (beta)-like 1, Y-linked 2.29995
SNAP91 synaptosomal-associated protein, 91kDa 2.2999
KAT6A K(lysine) acetyltransferase 6A 2.29857
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.2965
CER1 cerberus 1, DAN family BMP antagonist 2.29555
MIS18A MIS18 kinetochore protein A 2.29335
DUX4 double homeobox 4 2.28265
PRSS2 protease, serine, 2 (trypsin 2) 2.27895
CRYBG3 beta-gamma crystallin domain containing 3 2.27605
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.2753
NMUR1 neuromedin U receptor 1 2.26875
ATXN7L1 ataxin 7-like 1 2.2652
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.2615
LYN LYN proto-oncogene, Src family tyrosine kinase 2.25948
CNOT1 CCR4-NOT transcription complex, subunit 1 2.25763
ATG13 autophagy related 13 2.2555
ACO1 aconitase 1, soluble 2.2543
GLB1L galactosidase, beta 1-like 2.25365
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.25085
CAV3 caveolin 3 2.2508
YBX2 Y box binding protein 2 2.24995
CCL21 chemokine (C-C motif) ligand 21 2.24585
DUSP10 dual specificity phosphatase 10 2.2439
CLINT1 clathrin interactor 1 2.24178
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.2413
DYSF dysferlin 2.2351
NECTIN1 nectin cell adhesion molecule 1 2.23222
ANKRD10 ankyrin repeat domain 10 2.23175
SPATA31A3 SPATA31 subfamily A, member 3 2.23145
KLK15 kallikrein-related peptidase 15 2.23125
CHMP6 charged multivesicular body protein 6 2.2302
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.2301
FSCN2 fascin actin-bundling protein 2, retinal 2.2299
FGF6 fibroblast growth factor 6 2.2247
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.2222
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.2217
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.22005
THBS4 thrombospondin 4 2.2185
MINDY3 MINDY lysine 48 deubiquitinase 3 2.21815
CCKAR cholecystokinin A receptor 2.2164
MXD3 MAX dimerization protein 3 2.2153
NKX3-1 NK3 homeobox 1 2.21507
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.215
GATA2 GATA binding protein 2 2.2141
RCVRN recoverin 2.2125
KLHL1 kelch-like family member 1 2.20925
GALR2 galanin receptor 2 2.20835
VCX3A variable charge, X-linked 3A 2.20757
PCDHB1 protocadherin beta 1 2.20525
MYOD1 myogenic differentiation 1 2.20185
ZCCHC24 zinc finger, CCHC domain containing 24 2.2012
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.2002
EID1 EP300 interacting inhibitor of differentiation 1 2.19878
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.19535
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.1946
WRAP53 WD repeat containing, antisense to TP53 2.1926
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.18785
CST2 cystatin SA 2.187
CEMP1 cementum protein 1 2.1864
PNLIPRP1 pancreatic lipase-related protein 1 2.18558
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.18485
PARP8 poly (ADP-ribose) polymerase family, member 8 2.18445
ZSCAN2 zinc finger and SCAN domain containing 2 2.18205
PHOX2B paired-like homeobox 2b 2.182
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.18025
ADAMTSL2 ADAMTS-like 2 2.17955
NXF2B nuclear RNA export factor 2B 2.17933
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.17555
DNASE1 deoxyribonuclease I 2.1709
NAP1L2 nucleosome assembly protein 1-like 2 2.16905
UPK3A uroplakin 3A 2.167
ADGRE3 adhesion G protein-coupled receptor E3 2.16695
PLEC plectin 2.1631
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.16225
FGF8 fibroblast growth factor 8 (androgen-induced) 2.1605
TREH trehalase (brush-border membrane glycoprotein) 2.157
FZD7 frizzled class receptor 7 2.15485
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.15425
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.1521
PRDM8 PR domain containing 8 2.15185
CTRC chymotrypsin C (caldecrin) 2.1515
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 2.14915
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 2.14845
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.1474
AMELY amelogenin, Y-linked 2.1468
SIGLEC9 sialic acid binding Ig-like lectin 9 2.14655
CRH corticotropin releasing hormone 2.14615
IL23A interleukin 23, alpha subunit p19 2.14595
MOGAT2 monoacylglycerol O-acyltransferase 2 2.14398
MTMR10 myotubularin related protein 10 2.1426
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.1421
LOC122526780 uncharacterized LOC122526780 2.14165
SNTG2 syntrophin, gamma 2 2.14015
ADGRB3 adhesion G protein-coupled receptor B3 2.13885
ODAD2 outer dynein arm docking complex subunit 2 2.13815
AFF2 AF4/FMR2 family, member 2 2.13273
CEND1 cell cycle exit and neuronal differentiation 1 2.13095
SOX21 SRY (sex determining region Y)-box 21 2.1295
POM121 POM121 transmembrane nucleoporin 2.1259
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.1239
CCIN calicin 2.1235
SOX1 SRY (sex determining region Y)-box 1 2.1204
LOC107985101 uncharacterized LOC107985101 2.11895
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.1152
MRPL19 mitochondrial ribosomal protein L19 2.11395
EXOSC4 exosome component 4 2.11308
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.11037
COQ8A coenzyme Q8A 2.10865
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.1086
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.10807
CTRL chymotrypsin-like 2.10795
HRH2 histamine receptor H2 2.10485
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.10275
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 2.10195
IRAK3 interleukin-1 receptor-associated kinase 3 2.09833
EDN2 endothelin 2 2.09755
SPTB spectrin, beta, erythrocytic 2.09725
UTP11 UTP11 small subunit processome component 2.096
CD5 CD5 molecule 2.0947
TLX2 T-cell leukemia homeobox 2 2.08875
PKNOX2 PBX/knotted 1 homeobox 2 2.08873
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.0886
SYTL2 synaptotagmin-like 2 2.08675
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 2.0821
CD101 CD101 molecule 2.07795
DNAAF11 dynein axonemal assembly factor 11 2.07745
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.0735
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.0724
STAB1 stabilin 1 2.07037
LRRN3 leucine rich repeat neuronal 3 2.06673
ZNF24 zinc finger protein 24 2.06528
TGFBI transforming growth factor, beta-induced, 68kDa 2.06445
HROB homologous recombination factor with OB-fold 2.0609
NKX3-2 NK3 homeobox 2 2.0594
TRAK2 trafficking protein, kinesin binding 2 2.05643
SSX3 synovial sarcoma, X breakpoint 3 2.04982
TACR2 tachykinin receptor 2 2.04845
ZNHIT2 zinc finger, HIT-type containing 2 2.04805
CRTC1 CREB regulated transcription coactivator 1 2.0474
WIPF2 WAS/WASL interacting protein family, member 2 2.04738
ZBTB25 zinc finger and BTB domain containing 25 2.04525
RAX retina and anterior neural fold homeobox 2.0416
MINAR1 membrane integral NOTCH2 associated receptor 1 2.0407
GFRA4 GDNF family receptor alpha 4 2.0403
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 2.03883
CTNNA3 catenin (cadherin-associated protein), alpha 3 2.0388
CDC45 cell division cycle 45 2.03865
PCDHA10 protocadherin alpha 10 2.03605
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.03338
CHODL chondrolectin 2.03325
GRK2 G protein-coupled receptor kinase 2 2.0305
RIBC2 RIB43A domain with coiled-coils 2 2.03015
PRM2 protamine 2 2.03005
DGKG diacylglycerol kinase, gamma 90kDa 2.0298
PNMA3 paraneoplastic Ma antigen 3 2.0296
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.02915
MXRA8 matrix-remodelling associated 8 2.02915
FOXH1 forkhead box H1 2.02915
DSCAM Down syndrome cell adhesion molecule 2.02768
AMHR2 anti-Mullerian hormone receptor, type II 2.027
VIPR2 vasoactive intestinal peptide receptor 2 2.0269
PHAF1 phagosome assembly factor 1 2.02655
CYSLTR2 cysteinyl leukotriene receptor 2 2.0232
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.02205
EPHX3 epoxide hydrolase 3 2.02175
NANOS3 nanos homolog 3 (Drosophila) 2.02025
NECAB3 N-terminal EF-hand calcium binding protein 3 2.0191
F5 coagulation factor V (proaccelerin, labile factor) 2.01807
AURKC aurora kinase C 2.0167
SUSD4 sushi domain containing 4 2.01525
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.01373
HDAC11 histone deacetylase 11 2.01355
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.012
PRPH2 peripherin 2 (retinal degeneration, slow) 2.01038
AQP2 aquaporin 2 (collecting duct) 2.0096
FRS3 fibroblast growth factor receptor substrate 3 2.00895
MPDU1 mannose-P-dolichol utilization defect 1 2.0061
RAB32 RAB32, member RAS oncogene family 2.00285
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.0024
WNT7B wingless-type MMTV integration site family, member 7B 2.0007
GML glycosylphosphatidylinositol anchored molecule like 2.0004
PADI3 peptidyl arginine deiminase, type III 2.0001

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -7.24405
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -5.60835
KDM3A lysine (K)-specific demethylase 3A -5.4693
CASP7 caspase 7, apoptosis-related cysteine peptidase -5.37895
RGS2 regulator of G-protein signaling 2 -5.16955
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.0854
SLC35B1 solute carrier family 35, member B1 -4.97185
NGRN neugrin, neurite outgrowth associated -4.9204
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.8053
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.7746
SLC35F2 solute carrier family 35, member F2 -4.68325
CCNB2 cyclin B2 -4.58925
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.36495
BLMH bleomycin hydrolase -4.27045
CDC20 cell division cycle 20 -4.2518
CHMP4B charged multivesicular body protein 4B -4.11438
CASP3 caspase 3, apoptosis-related cysteine peptidase -4.076
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.86395
TRAP1 TNF receptor-associated protein 1 -3.85095
MVP major vault protein -3.71635
TBC1D31 TBC1 domain family, member 31 -3.6263
MSH2 mutS homolog 2 -3.608
AKAP8 A kinase (PRKA) anchor protein 8 -3.6045
ADI1 acireductone dioxygenase 1 -3.50375
ASCC3 activating signal cointegrator 1 complex subunit 3 -3.47405
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.32235
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.2033
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -3.10355
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -3.09623
RPS5 ribosomal protein S5 -3.0894
TMEM147 transmembrane protein 147 -3.0512
MCM3 minichromosome maintenance complex component 3 -3.0173
PCNA proliferating cell nuclear antigen -3.0091
REEP5 receptor accessory protein 5 -3.00822
ARID5B AT rich interactive domain 5B (MRF1-like) -2.9772
CRTC3 CREB regulated transcription coactivator 3 -2.8908
MAPK13 mitogen-activated protein kinase 13 -2.884
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.867
ORC3 origin recognition complex, subunit 3 -2.77745
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -2.76305
CYBC1 cytochrome b-245 chaperone 1 -2.73055
USP6NL USP6 N-terminal like -2.7057
CAB39 calcium binding protein 39 -2.6874
PIBF1 progesterone immunomodulatory binding factor 1 -2.6767
TRIM13 tripartite motif containing 13 -2.6729
TTK TTK protein kinase -2.6599
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.6392
WDR7 WD repeat domain 7 -2.63755
GTPBP8 GTP-binding protein 8 (putative) -2.6292
GRN granulin -2.6047
YES1 YES proto-oncogene 1, Src family tyrosine kinase -2.58533
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.5738
PRCP prolylcarboxypeptidase (angiotensinase C) -2.57245
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -2.56914
DUSP14 dual specificity phosphatase 14 -2.5583
IRF1 interferon regulatory factor 1 -2.55675
FAIM Fas apoptotic inhibitory molecule -2.5557
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.5387
DCAF6 DDB1 and CUL4 associated factor 6 -2.5381
TRAPPC6A trafficking protein particle complex 6A -2.53445
NPDC1 neural proliferation, differentiation and control, 1 -2.49875
OPTN optineurin -2.48885
CDC34 cell division cycle 34 -2.4638
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.4209
RFC2 replication factor C (activator 1) 2, 40kDa -2.39765
RPN1 ribophorin I -2.39105
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.36197
APOL3 apolipoprotein L, 3 -2.351
OBI1 ORC ubiquitin ligase 1 -2.34655
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.33993
PPL periplakin -2.33425
KIF14 kinesin family member 14 -2.32985
CHEK1 checkpoint kinase 1 -2.32207
NUP43 nucleoporin 43kDa -2.31715
TBCB tubulin folding cofactor B -2.31357
KIZ kizuna centrosomal protein -2.30595
LY75-CD302 LY75-CD302 readthrough -2.29855
LGMN legumain -2.2598
SPATS2 spermatogenesis associated, serine-rich 2 -2.2564
TICAM1 toll-like receptor adaptor molecule 1 -2.2562
RNF187 ring finger protein 187 -2.23885
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -2.2369
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.23385
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.22214
SREK1IP1 SREK1-interacting protein 1 -2.21825
CCDC92 coiled-coil domain containing 92 -2.21355
RNMT RNA (guanine-7-) methyltransferase -2.2098
HBD hemoglobin, delta -2.2
RPIA ribose 5-phosphate isomerase A -2.1987
HOXA10-HOXA9 HOXA10-HOXA9 readthrough -2.1971
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.1854
TBC1D10C TBC1 domain family, member 10C -2.1556
TFCP2 transcription factor CP2 -2.15473
HOPX HOP homeobox -2.152
NDC80 NDC80 kinetochore complex component -2.14695
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.1455
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -2.1234
RHEB Ras homolog enriched in brain -2.11607
GPKOW G patch domain and KOW motifs -2.1067
LAGE3 L antigen family, member 3 -2.09665
PERP PERP, TP53 apoptosis effector -2.08715
GHR growth hormone receptor -2.085
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.0767
CRYAB crystallin, alpha B -2.06275
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.06223
TMEM135 transmembrane protein 135 -2.06215
RHOT1 ras homolog family member T1 -2.0609
HSPE1 heat shock 10kDa protein 1 -2.0454
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.045
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -2.0401
PRKCD protein kinase C, delta -2.0091
ANXA4 annexin A4 -2.00145
H2BC12 H2B clustered histone 12 -2.0004