CRCGN011_HEPG2_24H:C09 Gene Set
Genes
33 genes differentially expressed following the CRCGN011_HEPG2_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
5.73125
|
|
STIMATE
|
STIM activating enhancer
|
5.57515
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.4818
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.8466
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
4.52695
|
|
EPHB2
|
EPH receptor B2
|
4.47595
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.22207
|
|
CYCS
|
cytochrome c, somatic
|
4.13595
|
|
CHN1
|
chimerin 1
|
3.11565
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.60813
|
|
ZNF589
|
zinc finger protein 589
|
2.5107
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.25055
|
|
NVL
|
nuclear VCP-like
|
2.18425
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.033
|
|
SDHAF3
|
succinate dehydrogenase complex assembly factor 3
|
2.0241
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.0179
|
|
MRPL4
|
mitochondrial ribosomal protein L4
|
2.01295
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.8122
|
|
GNAS
|
GNAS complex locus
|
-7.151
|
|
ZW10
|
zw10 kinetochore protein
|
-5.32795
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.7455
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.62725
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.50635
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.7885
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.68287
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.6801
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.50995
|
|
ITPKC
|
inositol-trisphosphate 3-kinase C
|
-2.42035
|
|
CRIP2
|
cysteine-rich protein 2
|
-2.3816
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.33581
|
|
FAT1
|
FAT atypical cadherin 1
|
-2.16055
|
|
PCBP3
|
poly(rC) binding protein 3
|
-2.06345
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
-2.01535
|