| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | caprolactam 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN011_HEPG2_24H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.9482 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.2036 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.15195 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.84915 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.81131 |
| CSK | c-src tyrosine kinase | 4.66275 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.6368 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.50615 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.4237 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 4.12855 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.76723 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.628 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.314 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.26065 |
| ABHD6 | abhydrolase domain containing 6 | 3.21083 |
| GPATCH8 | G patch domain containing 8 | 2.92115 |
| MICALL1 | MICAL-like 1 | 2.80147 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | 2.7458 |
| PVALB | parvalbumin | 2.6024 |
| UTP11 | UTP11 small subunit processome component | 2.6016 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.5165 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.4885 |
| RBM22 | RNA binding motif protein 22 | 2.4398 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 2.28775 |
| SIX1 | SIX homeobox 1 | 2.2667 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.23155 |
| SNUPN | snurportin 1 | 2.184 |
| ZMYM2 | zinc finger, MYM-type 2 | 2.16643 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.1287 |
| CHN1 | chimerin 1 | 2.1219 |
| NOSIP | nitric oxide synthase interacting protein | 2.07005 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.03428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -6.01975 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -5.2227 |
| DNM1L | dynamin 1-like | -5.2048 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.0 |
| THAP11 | THAP domain containing 11 | -4.9261 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.74425 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.646 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.5672 |
| MAP7 | microtubule-associated protein 7 | -4.43705 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.85315 |
| RNF167 | ring finger protein 167 | -3.7308 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.0412 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.01038 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.6332 |
| SNX11 | sorting nexin 11 | -2.6024 |
| SHTN1 | shootin 1 | -2.55555 |
| PON3 | paraoxonase 3 | -2.48425 |
| EXT1 | exostosin glycosyltransferase 1 | -2.44755 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -2.3973 |
| CLDN7 | claudin 7 | -2.31115 |
| KLHL2 | kelch-like family member 2 | -2.28685 |
| RAD51C | RAD51 paralog C | -2.17302 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein | -2.16685 |
| TBK1 | TANK-binding kinase 1 | -2.1529 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | -2.15255 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -2.1449 |
| ITGA7 | integrin, alpha 7 | -2.11943 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -2.085 |
| CCN5 | cellular communication network factor 5 | -2.06635 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -2.0492 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -2.0456 |
| SLC17A4 | solute carrier family 17, member 4 | -2.03145 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -2.0184 |
