| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | maleic hydrazide 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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93 genes differentially expressed following the CRCGN011_HEPG2_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.60525 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.3066 |
| LCN2 | lipocalin 2 | 5.0 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.90475 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.85575 |
| STIMATE | STIM activating enhancer | 4.74885 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.72703 |
| RPL39L | ribosomal protein L39-like | 4.70335 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.61245 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 4.43405 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.12901 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.619 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.45485 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 3.39723 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.1195 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.115 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.96425 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 2.7164 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 2.51615 |
| EVL | Enah/Vasp-like | 2.49435 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.48275 |
| NUTF2 | nuclear transport factor 2 | 2.4241 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 2.38755 |
| DIPK1A | divergent protein kinase domain 1A | 2.38665 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.36085 |
| TMEM123 | transmembrane protein 123 | 2.28655 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 2.2456 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 2.22815 |
| RPGR | retinitis pigmentosa GTPase regulator | 2.22715 |
| CCNE2 | cyclin E2 | 2.1869 |
| CTSZ | cathepsin Z | 2.1846 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 2.15838 |
| THOC1 | THO complex 1 | 2.1526 |
| RBMX2 | RNA binding motif protein, X-linked 2 | 2.14878 |
| EPHA3 | EPH receptor A3 | 2.148 |
| SP3 | Sp3 transcription factor | 2.13515 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 2.1308 |
| SDC2 | syndecan 2 | 2.09788 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 2.09285 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 2.08495 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 2.06255 |
| NME5 | NME/NM23 family member 5 | 2.0604 |
| ICAM3 | intercellular adhesion molecule 3 | 2.05635 |
| RAB5C | RAB5C, member RAS oncogene family | 2.0548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -9.4754 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -9.3817 |
| MRPS2 | mitochondrial ribosomal protein S2 | -6.27 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.5204 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.295 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.20695 |
| LDHD | lactate dehydrogenase D | -5.02335 |
| DNM1L | dynamin 1-like | -5.0 |
| TXNRD1 | thioredoxin reductase 1 | -4.4134 |
| PCNA | proliferating cell nuclear antigen | -3.7881 |
| CASP8AP2 | caspase 8 associated protein 2 | -3.226 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.02165 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.7884 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.77605 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.6993 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.5806 |
| HPS5 | Hermansky-Pudlak syndrome 5 | -2.56305 |
| CA2 | carbonic anhydrase II | -2.51385 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.51185 |
| KXD1 | KxDL motif containing 1 | -2.4987 |
| EBI3 | Epstein-Barr virus induced 3 | -2.49225 |
| RCC1L | RCC1 like | -2.49135 |
| MED15 | mediator complex subunit 15 | -2.46775 |
| CAVIN2 | caveolae associated protein 2 | -2.4396 |
| CDIP1 | cell death-inducing p53 target 1 | -2.39915 |
| HEATR1 | HEAT repeat containing 1 | -2.39717 |
| E4F1 | E4F transcription factor 1 | -2.39105 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.35877 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -2.3523 |
| SLC22A17 | solute carrier family 22, member 17 | -2.31325 |
| SHPK | sedoheptulokinase | -2.27445 |
| MED22 | mediator complex subunit 22 | -2.2386 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | -2.23275 |
| HMOX2 | heme oxygenase 2 | -2.22725 |
| ZNF500 | zinc finger protein 500 | -2.22662 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.2166 |
| SNN | stannin | -2.19322 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -2.17985 |
| NUP43 | nucleoporin 43kDa | -2.16305 |
| RNF167 | ring finger protein 167 | -2.10965 |
| FOXN1 | forkhead box N1 | -2.10785 |
| WBP2 | WW domain binding protein 2 | -2.0867 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -2.074 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -2.0639 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -2.05715 |
| MTO1 | mitochondrial tRNA translation optimization 1 | -2.05375 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | -2.043 |
| PLEK | pleckstrin | -2.02413 |
| GCDH | glutaryl-CoA dehydrogenase | -2.01627 |
