| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | maleic hydrazide 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN011_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DYNLT3 | dynein, light chain, Tctex-type 3 | 6.44815 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.6124 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.418 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.3322 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.23235 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.1163 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.67035 |
| DENND2D | DENN/MADD domain containing 2D | 4.19365 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.0916 |
| ATP11B | ATPase, class VI, type 11B | 4.03375 |
| STIMATE | STIM activating enhancer | 3.90335 |
| MAP7 | microtubule-associated protein 7 | 3.8965 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.8476 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.2959 |
| MEST | mesoderm specific transcript | 2.6901 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.6585 |
| MX1 | MX dynamin-like GTPase 1 | 2.59895 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.3521 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.19237 |
| FASTKD5 | FAST kinase domains 5 | 2.1749 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 2.16205 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 2.06822 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.0486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.78825 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.34685 |
| NUP85 | nucleoporin 85kDa | -4.91795 |
| LDHD | lactate dehydrogenase D | -4.83055 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.5401 |
| CCNB2 | cyclin B2 | -4.43825 |
| CHMP4B | charged multivesicular body protein 4B | -4.39355 |
| GNAS | GNAS complex locus | -3.32737 |
| VDAC1 | voltage-dependent anion channel 1 | -3.18157 |
| GDF15 | growth differentiation factor 15 | -3.16995 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.0749 |
| HEATR1 | HEAT repeat containing 1 | -3.04122 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.83235 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.8036 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.74885 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.74113 |
| RPS5 | ribosomal protein S5 | -2.71405 |
| PRPF4 | pre-mRNA processing factor 4 | -2.65943 |
| SAP30BP | SAP30 binding protein | -2.63685 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.5465 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.3753 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.3527 |
| TLCD3A | TLC domain containing 3A | -2.3071 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.26702 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.2524 |
| WBP2 | WW domain binding protein 2 | -2.20235 |
| NT5C | 5', 3'-nucleotidase, cytosolic | -2.19885 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.193 |
| TXNRD1 | thioredoxin reductase 1 | -2.16845 |
| GRB2 | growth factor receptor-bound protein 2 | -2.1611 |
| SLC35F2 | solute carrier family 35, member F2 | -2.1285 |
| RNF167 | ring finger protein 167 | -2.10475 |
| OSMR | oncostatin M receptor | -2.0877 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.03825 |
