CRCGN011_HEPG2_24H:C15 Gene Set
Genes
55 genes differentially expressed following the CRCGN011_HEPG2_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
9.93895
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
5.9521
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.28065
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
5.27531
|
|
CSK
|
c-src tyrosine kinase
|
5.08485
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.02735
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.8819
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
4.8216
|
|
TLR4
|
toll-like receptor 4
|
4.76975
|
|
STIMATE
|
STIM activating enhancer
|
4.1165
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
4.01585
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.61133
|
|
NMU
|
neuromedin U
|
3.5083
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.40943
|
|
FZD7
|
frizzled class receptor 7
|
2.63433
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.61605
|
|
EPHA3
|
EPH receptor A3
|
2.56648
|
|
WDR7
|
WD repeat domain 7
|
2.4318
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.41985
|
|
MYOZ1
|
myozenin 1
|
2.37905
|
|
TMUB2
|
transmembrane and ubiquitin-like domain containing 2
|
2.26105
|
|
ZFPM2
|
zinc finger protein, FOG family member 2
|
2.21145
|
|
HEBP1
|
heme binding protein 1
|
2.183
|
|
ACTC1
|
actin, alpha, cardiac muscle 1
|
2.17695
|
|
VGLL4
|
vestigial-like family member 4
|
2.11735
|
|
BDKRB2
|
bradykinin receptor B2
|
2.0853
|
|
ZNF589
|
zinc finger protein 589
|
2.08013
|
|
CYCS
|
cytochrome c, somatic
|
2.0578
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.04135
|
|
TCF21
|
transcription factor 21
|
2.0101
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.343
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.44585
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.19945
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.0219
|
|
DNM1L
|
dynamin 1-like
|
-5.0
|
|
ZW10
|
zw10 kinetochore protein
|
-4.944
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.8375
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.7725
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.50975
|
|
CDC25B
|
cell division cycle 25B
|
-3.54865
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.4882
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.3338
|
|
GNAS
|
GNAS complex locus
|
-3.17506
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.08665
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.87865
|
|
JPT2
|
Jupiter microtubule associated homolog 2
|
-2.36463
|
|
CSNK1E
|
casein kinase 1, epsilon
|
-2.26918
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.22303
|
|
APOC3
|
apolipoprotein C-III
|
-2.22115
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.12356
|
|
FOXRED2
|
FAD-dependent oxidoreductase domain containing 2
|
-2.0908
|
|
EPHX1
|
epoxide hydrolase 1, microsomal (xenobiotic)
|
-2.0843
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.0459
|
|
ATP6V0C
|
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
|
-2.0334
|
|
FMO3
|
flavin containing monooxygenase 3
|
-2.0327
|
