| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | maleic hydrazide 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN011_HEPG2_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 6.2207 |
| MCOLN1 | mucolipin 1 | 5.6665 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.37985 |
| SQOR | sulfide quinone oxidoreductase | 4.84565 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.71165 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.61685 |
| STIMATE | STIM activating enhancer | 4.5908 |
| DENND2D | DENN/MADD domain containing 2D | 4.5486 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.15385 |
| PLSCR3 | phospholipid scramblase 3 | 3.92 |
| ABHD6 | abhydrolase domain containing 6 | 3.61143 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.564 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 3.5517 |
| FZD7 | frizzled class receptor 7 | 3.49367 |
| ATP11B | ATPase, class VI, type 11B | 3.07025 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 2.9015 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.77095 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.71355 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 2.5734 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 2.5053 |
| COL11A1 | collagen, type XI, alpha 1 | 2.50402 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.42605 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.41055 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.39132 |
| GPATCH8 | G patch domain containing 8 | 2.38263 |
| FPGS | folylpolyglutamate synthase | 2.33165 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.3171 |
| SIRT3 | sirtuin 3 | 2.26605 |
| ANXA6 | annexin A6 | 2.2137 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 2.18385 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 2.06455 |
| CD59 | CD59 molecule, complement regulatory protein | 2.05933 |
| P3H1 | prolyl 3-hydroxylase 1 | 2.05695 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 2.05265 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 2.0225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.1479 |
| LDHD | lactate dehydrogenase D | -5.11295 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| CD320 | CD320 molecule | -4.8516 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| CDC20 | cell division cycle 20 | -4.66275 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.5544 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.1093 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.57405 |
| GNAS | GNAS complex locus | -3.54142 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.52385 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.48805 |
| PCNA | proliferating cell nuclear antigen | -3.42015 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.3591 |
| BECN1 | beclin 1, autophagy related | -3.25598 |
| WASHC4 | WASH complex subunit 4 | -3.19128 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.9729 |
| CCNB2 | cyclin B2 | -2.812 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.73875 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.53805 |
| RNF167 | ring finger protein 167 | -2.4878 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.43102 |
| NLGN1 | neuroligin 1 | -2.31485 |
| ZNF586 | zinc finger protein 586 | -2.30745 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.2832 |
| TASP1 | taspase, threonine aspartase, 1 | -2.20625 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.20022 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.1892 |
| SLC35F2 | solute carrier family 35, member F2 | -2.1333 |
| CHMP1A | charged multivesicular body protein 1A | -2.11505 |
