| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-phenyl-p-phenylenediamine.hcl 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
89 genes differentially expressed following the CRCGN011_HEPG2_24H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 8.61805 |
| CBR3 | carbonyl reductase 3 | 5.64375 |
| CHMP6 | charged multivesicular body protein 6 | 5.4069 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.3737 |
| RPL39L | ribosomal protein L39-like | 5.36755 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.3673 |
| PRR15L | proline rich 15-like | 5.2763 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.19815 |
| STIMATE | STIM activating enhancer | 5.02995 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.9223 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.75565 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.72495 |
| DENND2D | DENN/MADD domain containing 2D | 4.6098 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 4.5941 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.44095 |
| HOXA10 | homeobox A10 | 4.3716 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 4.01575 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.5792 |
| ABHD6 | abhydrolase domain containing 6 | 3.55745 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.53333 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 3.487 |
| EPHB2 | EPH receptor B2 | 3.20351 |
| COL11A1 | collagen, type XI, alpha 1 | 3.05185 |
| MEST | mesoderm specific transcript | 3.0105 |
| ZNF589 | zinc finger protein 589 | 2.84505 |
| PRKCH | protein kinase C, eta | 2.51207 |
| DIPK1A | divergent protein kinase domain 1A | 2.45797 |
| CHN1 | chimerin 1 | 2.44685 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.40562 |
| EPHA3 | EPH receptor A3 | 2.39685 |
| LOC124908558 | X antigen family member 1-like | 2.381 |
| EDN1 | endothelin 1 | 2.3343 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.27645 |
| HOXA11 | homeobox A11 | 2.27268 |
| SERHL2 | serine hydrolase-like 2 | 2.26413 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 2.2544 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.2402 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.2128 |
| SCTR | secretin receptor | 2.16945 |
| CEP131 | centrosomal protein 131kDa | 2.1075 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.09288 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 2.05605 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | 2.0471 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.03443 |
| SOX1 | SRY (sex determining region Y)-box 1 | 2.02395 |
| TRAF5 | TNF receptor-associated factor 5 | 2.0098 |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 2.00805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.6162 |
| CCDC86 | coiled-coil domain containing 86 | -5.28665 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.98785 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.96725 |
| LDHD | lactate dehydrogenase D | -4.87005 |
| ISOC1 | isochorismatase domain containing 1 | -4.8613 |
| CCNB2 | cyclin B2 | -4.84855 |
| RPS5 | ribosomal protein S5 | -4.83295 |
| ADI1 | acireductone dioxygenase 1 | -4.7463 |
| DNM1L | dynamin 1-like | -4.5736 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.01035 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.9542 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.7892 |
| GNAS | GNAS complex locus | -3.66129 |
| CAB39 | calcium binding protein 39 | -3.4102 |
| TCTN1 | tectonic family member 1 | -3.20535 |
| PCNA | proliferating cell nuclear antigen | -3.18175 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.9297 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.7101 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.67505 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.66325 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.56372 |
| EPS8L2 | EPS8-like 2 | -2.52365 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -2.42307 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.35805 |
| RPL39 | ribosomal protein L39 | -2.2806 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.27185 |
| PUM3 | pumilio RNA binding family member 3 | -2.24905 |
| TMEM260 | transmembrane protein 260 | -2.1987 |
| BSG | basigin (Ok blood group) | -2.17 |
| CSNK1G3 | casein kinase 1, gamma 3 | -2.162 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -2.1347 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -2.1206 |
| C5 | complement component 5 | -2.1171 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.11385 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | -2.0938 |
| RABL6 | RAB, member RAS oncogene family-like 6 | -2.08165 |
| RPL18 | ribosomal protein L18 | -2.07855 |
| BTBD1 | BTB (POZ) domain containing 1 | -2.0672 |
| RBM15B | RNA binding motif protein 15B | -2.03835 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.01985 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.01025 |
