| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-phenyl-p-phenylenediamine.hcl 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN011_HEPG2_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 5.6008 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.33085 |
| SQOR | sulfide quinone oxidoreductase | 5.2538 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.2474 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.0193 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.9903 |
| MOK | MOK protein kinase | 4.74445 |
| ATP11B | ATPase, class VI, type 11B | 4.0254 |
| COQ8A | coenzyme Q8A | 3.99295 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.47715 |
| FZD7 | frizzled class receptor 7 | 2.98093 |
| GPATCH8 | G patch domain containing 8 | 2.91608 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.6816 |
| RLIM | ring finger protein, LIM domain interacting | 2.4736 |
| NMU | neuromedin U | 2.36785 |
| TBXA2R | thromboxane A2 receptor | 2.2998 |
| GRB14 | growth factor receptor-bound protein 14 | 2.28125 |
| KLHL9 | kelch-like family member 9 | 2.27925 |
| MRPL44 | mitochondrial ribosomal protein L44 | 2.25105 |
| RPL36 | ribosomal protein L36 | 2.2256 |
| ACTMAP | actin maturation protease | 2.17915 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 2.17245 |
| BID | BH3 interacting domain death agonist | 2.16428 |
| PPT1 | palmitoyl-protein thioesterase 1 | 2.14365 |
| CHN1 | chimerin 1 | 2.10555 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 2.074 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.07385 |
| MZT2A | mitotic spindle organizing protein 2A | 2.05515 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | 2.05325 |
| OLA1 | Obg-like ATPase 1 | 2.0511 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | 2.0454 |
| CEP57 | centrosomal protein 57kDa | 2.03363 |
| FASTKD5 | FAST kinase domains 5 | 2.02815 |
| CDK7 | cyclin-dependent kinase 7 | 2.0122 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CCNB2 | cyclin B2 | -8.1808 |
| MAPK13 | mitogen-activated protein kinase 13 | -6.57285 |
| CD320 | CD320 molecule | -5.0 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.8463 |
| NUP85 | nucleoporin 85kDa | -4.60055 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.44955 |
| GDF15 | growth differentiation factor 15 | -3.64105 |
| GNAS | GNAS complex locus | -3.38549 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.29432 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -3.02915 |
| PCNA | proliferating cell nuclear antigen | -2.9925 |
| NGRN | neugrin, neurite outgrowth associated | -2.86955 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.73908 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -2.59148 |
| COL16A1 | collagen, type XVI, alpha 1 | -2.58265 |
| PCDHB3 | protocadherin beta 3 | -2.5564 |
| UBE3C | ubiquitin protein ligase E3C | -2.433 |
| NSUN3 | NOP2/Sun domain family, member 3 | -2.36115 |
| SLC38A12 | solute carrier family 38 member 12 | -2.3173 |
| ZNF586 | zinc finger protein 586 | -2.31555 |
| AURKB | aurora kinase B | -2.1976 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 | -2.18685 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.18235 |
| CCDC70 | coiled-coil domain containing 70 | -2.15145 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -2.1449 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) | -2.13235 |
| CEP76 | centrosomal protein 76kDa | -2.119 |
| PCDHB6 | protocadherin beta 6 | -2.1034 |
| ROM1 | retinal outer segment membrane protein 1 | -2.09455 |
| SDF4 | stromal cell derived factor 4 | -2.08798 |
| ETV7 | ets variant 7 | -2.0785 |
| SCTR | secretin receptor | -2.06655 |
| CD247 | CD247 molecule | -2.05345 |
| SNUPN | snurportin 1 | -2.04675 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | -2.04475 |
| NPTXR | neuronal pentraxin receptor | -2.0102 |
