| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-vinylpyrrolidone-2 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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102 genes differentially expressed following the CRCGN011_HEPG2_24H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.032 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.49575 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.09695 |
| ADRB2 | adrenoceptor beta 2, surface | 4.88935 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.80395 |
| STIMATE | STIM activating enhancer | 4.7357 |
| CBR3 | carbonyl reductase 3 | 4.60065 |
| EVL | Enah/Vasp-like | 4.4098 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.3951 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.22805 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.12675 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 3.9483 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.87305 |
| ABHD6 | abhydrolase domain containing 6 | 3.14437 |
| PMM2 | phosphomannomutase 2 | 2.78505 |
| F8A2 | coagulation factor VIII-associated 2 | 2.73215 |
| SETD1B | SET domain containing 1B | 2.69165 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 2.64475 |
| COQ8A | coenzyme Q8A | 2.6447 |
| BAX | BCL2-associated X protein | 2.63412 |
| TBXA2R | thromboxane A2 receptor | 2.59783 |
| CCNF | cyclin F | 2.5868 |
| KIFBP | kinesin family binding protein | 2.5841 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.52595 |
| LUC7L | LUC7-like (S. cerevisiae) | 2.3906 |
| CCDC85C | coiled-coil domain containing 85C | 2.36405 |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 2.338 |
| UBE4A | ubiquitination factor E4A | 2.33135 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.3303 |
| PRPF8 | pre-mRNA processing factor 8 | 2.29475 |
| WDR5B | WD repeat domain 5B | 2.2348 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 2.23148 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 2.2163 |
| TBC1D13 | TBC1 domain family, member 13 | 2.19753 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.18942 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 2.18715 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.1837 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 2.17275 |
| ADGRD2 | adhesion G protein-coupled receptor D2 | 2.1666 |
| MGMT | O-6-methylguanine-DNA methyltransferase | 2.1537 |
| SART3 | squamous cell carcinoma antigen recognized by T cells 3 | 2.11637 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 2.11635 |
| DEXI | Dexi homolog (mouse) | 2.11105 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin | 2.0785 |
| SH2B3 | SH2B adaptor protein 3 | 2.0714 |
| TP53TG5 | TP53 target 5 | 2.06415 |
| DENND1A | DENN/MADD domain containing 1A | 2.06345 |
| GYG1 | glycogenin 1 | 2.05632 |
| MFAP1 | microfibrillar-associated protein 1 | 2.0333 |
| OXR1 | oxidation resistance 1 | 2.0324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.266 |
| TLCD3A | TLC domain containing 3A | -6.92555 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.73995 |
| VAT1 | vesicle amine transport 1 | -5.31565 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -4.93585 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.90965 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.86515 |
| CCNB1 | cyclin B1 | -4.51055 |
| HMG20B | high mobility group 20B | -4.42118 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.22055 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.10625 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.76795 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -3.61745 |
| BLCAP | bladder cancer associated protein | -2.93385 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.7834 |
| TFCP2L1 | transcription factor CP2-like 1 | -2.76635 |
| SEC61G | Sec61 gamma subunit | -2.5959 |
| RBM34 | RNA binding motif protein 34 | -2.50522 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -2.5043 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | -2.4473 |
| MRPL11 | mitochondrial ribosomal protein L11 | -2.441 |
| ARL4A | ADP-ribosylation factor-like 4A | -2.417 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.41535 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -2.4099 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.40142 |
| ACLY | ATP citrate lyase | -2.39837 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.33452 |
| CCND2 | cyclin D2 | -2.33125 |
| PODNL1 | podocan-like 1 | -2.3131 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.29209 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -2.28122 |
| MSN | moesin | -2.2733 |
| NAALADL1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | -2.23135 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | -2.20295 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | -2.15995 |
| SOAT2 | sterol O-acyltransferase 2 | -2.1537 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -2.14695 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -2.138 |
| NTS | neurotensin | -2.1345 |
| COA3 | cytochrome c oxidase assembly factor 3 | -2.09955 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.0889 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -2.08165 |
| DDRGK1 | DDRGK domain containing 1 | -2.0769 |
| TMEM134 | transmembrane protein 134 | -2.06635 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -2.0383 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | -2.0296 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.0221 |
| EPS8L3 | EPS8-like 3 | -2.01365 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -2.01275 |
| H2AZ1 | H2A.Z variant histone 1 | -2.01047 |
| CAVIN1 | caveolae associated protein 1 | -2.00912 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) | -2.0016 |
