CRCGN011_HEPG2_24H:D09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-vinylpyrrolidone-2 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

471 genes differentially expressed following the CRCGN011_HEPG2_24H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SYNE2 spectrin repeat containing, nuclear envelope 2 6.2287
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.8861
PPARG peroxisome proliferator-activated receptor gamma 5.8385
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.76865
LOXL1 lysyl oxidase-like 1 5.693
UBQLN2 ubiquilin 2 5.64725
OXCT1 3-oxoacid CoA transferase 1 5.6469
ADRB2 adrenoceptor beta 2, surface 5.58755
STAP2 signal transducing adaptor family member 2 5.36125
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.21415
RPP38 ribonuclease P/MRP 38kDa subunit 5.2073
RPL39L ribosomal protein L39-like 5.13735
PLS1 plastin 1 5.0081
AMDHD2 amidohydrolase domain containing 2 4.9154
CIAO3 cytosolic iron-sulfur assembly component 3 4.76525
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.76495
SNAP25 synaptosomal-associated protein, 25kDa 4.72223
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.7123
TBPL1 TBP-like 1 4.65425
NENF neudesin neurotrophic factor 4.6123
MSRA methionine sulfoxide reductase A 4.61075
STK10 serine/threonine kinase 10 4.4291
MOK MOK protein kinase 4.3696
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.1654
CCDC92 coiled-coil domain containing 92 4.1058
PEX11A peroxisomal biogenesis factor 11 alpha 4.10087
CXCL2 chemokine (C-X-C motif) ligand 2 4.06055
PRKCH protein kinase C, eta 4.0518
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 4.04295
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.97487
ADAT1 adenosine deaminase, tRNA-specific 1 3.91255
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.86555
PARP1 poly (ADP-ribose) polymerase 1 3.8094
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.8088
PCDHB11 protocadherin beta 11 3.79759
JADE2 jade family PHD finger 2 3.75955
CCNA1 cyclin A1 3.75355
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.67905
EPN2 epsin 2 3.6502
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.62285
CYCS cytochrome c, somatic 3.62085
LOC122526780 uncharacterized LOC122526780 3.53255
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 3.4288
INSIG1 insulin induced gene 1 3.42552
ARMCX1 armadillo repeat containing, X-linked 1 3.4114
GRB10 growth factor receptor-bound protein 10 3.39367
IDE insulin-degrading enzyme 3.38652
FZD7 frizzled class receptor 7 3.32113
TAC4 tachykinin 4 (hemokinin) 3.2978
ABHD4 abhydrolase domain containing 4 3.2975
ADAM10 ADAM metallopeptidase domain 10 3.27417
DENND2D DENN/MADD domain containing 2D 3.2676
ADGRE5 adhesion G protein-coupled receptor E5 3.2589
DDB2 damage-specific DNA binding protein 2, 48kDa 3.20455
ZFY zinc finger protein, Y-linked 3.1736
CGRRF1 cell growth regulator with ring finger domain 1 3.14815
MAST2 microtubule associated serine/threonine kinase 2 3.11157
CCL2 chemokine (C-C motif) ligand 2 3.0531
PANK3 pantothenate kinase 3 3.0379
PTPN6 protein tyrosine phosphatase, non-receptor type 6 3.00135
SQOR sulfide quinone oxidoreductase 2.9899
BIRC2 baculoviral IAP repeat containing 2 2.9867
RXYLT1 ribitol xylosyltransferase 1 2.96125
ZBTB35 zinc finger and BTB domain containing 35 2.94872
CTPS2 CTP synthase 2 2.9481
TENM1 teneurin transmembrane protein 1 2.9384
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.92715
GPATCH8 G patch domain containing 8 2.88258
ABHD8 abhydrolase domain containing 8 2.86625
EDN1 endothelin 1 2.85505
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.85075
USO1 USO1 vesicle transport factor 2.83982
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.82735
ITGA6 integrin, alpha 6 2.77852
GPR143 G protein-coupled receptor 143 2.77165
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.76145
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 2.74935
GSTZ1 glutathione S-transferase zeta 1 2.74865
NPPB natriuretic peptide B 2.7351
RNF146 ring finger protein 146 2.728
GPER1 G protein-coupled estrogen receptor 1 2.72357
FSCN2 fascin actin-bundling protein 2, retinal 2.7221
TEX10 testis expressed 10 2.7177
KRT15 keratin 15, type I 2.7115
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.69235
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.68928
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.68615
RPL36AL ribosomal protein L36a-like 2.6671
B3GAT3 beta-1,3-glucuronyltransferase 3 2.64192
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.6282
KCNK12 potassium channel, two pore domain subfamily K, member 12 2.6101
PTK2 protein tyrosine kinase 2 2.6084
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.59105
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.58745
GDAP1 ganglioside induced differentiation associated protein 1 2.57205
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.5655
MAP7D3 MAP7 domain containing 3 2.56488
DELE1 DAP3 binding cell death enhancer 1 2.55885
E2F2 E2F transcription factor 2 2.53835
MMP10 matrix metallopeptidase 10 2.5306
CEP97 centrosomal protein 97kDa 2.5151
TAC1 tachykinin, precursor 1 2.5061
MNMIP1 manchette microtubule inner protein 1 2.4994
GRM4 glutamate receptor, metabotropic 4 2.49785
FZD8 frizzled class receptor 8 2.493
CAPN1 calpain 1, (mu/I) large subunit 2.4873
SMAP1 small ArfGAP 1 2.4867
LCN2 lipocalin 2 2.47775
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.4616
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.45385
OGFRL1 opioid growth factor receptor-like 1 2.4479
CEP15 centrosomal protein 15 2.4465
RSBN1 round spermatid basic protein 1 2.4425
ZNF215 zinc finger protein 215 2.4395
RIOX1 ribosomal oxygenase 1 2.4363
FBXO41 F-box protein 41 2.43575
SLC25A46 solute carrier family 25, member 46 2.4348
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.428
NT5E 5'-nucleotidase, ecto (CD73) 2.4224
WDR25 WD repeat domain 25 2.4217
CD79B CD79b molecule, immunoglobulin-associated beta 2.41095
ZFYVE21 zinc finger, FYVE domain containing 21 2.41
LOC128966622 putative protein N-methyltransferase FAM86B2 2.40885
MATN4 matrilin 4 2.4082
BTK Bruton agammaglobulinemia tyrosine kinase 2.40265
ISG20 interferon stimulated exonuclease gene 20kDa 2.39835
PDZD7 PDZ domain containing 7 2.3886
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.38605
KLF2 Kruppel-like factor 2 2.3835
RBM38 RNA binding motif protein 38 2.3809
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.37805
NPY4R2 neuropeptide Y receptor Y4-2 2.37375
LOC124904942 uncharacterized LOC124904942 2.36752
PCDHGA10 protocadherin gamma subfamily A, 10 2.36725
ARHGAP32 Rho GTPase activating protein 32 2.34048
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.33925
ULBP2 UL16 binding protein 2 2.3389
THSD7A thrombospondin, type I, domain containing 7A 2.33455
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.33185
PARD6A par-6 family cell polarity regulator alpha 2.3317
DPP3 dipeptidyl-peptidase 3 2.3309
EPHA3 EPH receptor A3 2.32303
OVOL3 ovo-like zinc finger 3 2.3169
CD40 CD40 molecule, TNF receptor superfamily member 5 2.31488
ZNF423 zinc finger protein 423 2.3137
FBXO11 F-box protein 11 2.31253
USP11 ubiquitin specific peptidase 11 2.31095
THBS4 thrombospondin 4 2.3079
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 2.30465
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.3025
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.299
AANAT aralkylamine N-acetyltransferase 2.2977
WNT7B wingless-type MMTV integration site family, member 7B 2.2964
PADI3 peptidyl arginine deiminase, type III 2.29395
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.2897
GJA3 gap junction protein, alpha 3, 46kDa 2.28635
TMEM143 transmembrane protein 143 2.28395
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.28253
DGKB diacylglycerol kinase, beta 90kDa 2.2773
VRK1 vaccinia related kinase 1 2.2761
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.26885
CREB1 cAMP responsive element binding protein 1 2.26264
AQP8 aquaporin 8 2.25475
LAMB3 laminin, beta 3 2.25125
H2BC12 H2B clustered histone 12 2.2454
PCDHGA11 protocadherin gamma subfamily A, 11 2.24085
AQP6 aquaporin 6, kidney specific 2.23745
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.2333
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.2325
PALS1 protein associated with LIN7 1, MAGUK p55 family member 2.23175
CT55 cancer/testis antigen 55 2.2299
EIF5A2 eukaryotic translation initiation factor 5A2 2.2278
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.22545
COL11A1 collagen, type XI, alpha 1 2.2195
RWDD2B RWD domain containing 2B 2.2187
ZFC3H1 zinc finger, C3H1-type containing 2.2163
CBARP CACN subunit beta associated regulatory protein 2.21245
LINC02854 long intergenic non-protein coding RNA 2854 2.20955
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.20395
EID1 EP300 interacting inhibitor of differentiation 1 2.1968
SMIM40 small integral membrane protein 40 2.19675
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.1966
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.18695
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.1858
CALB2 calbindin 2 2.1798
COL6A2 collagen, type VI, alpha 2 2.17442
TMEM243 transmembrane protein 243, mitochondrial 2.17365
BTG1 B-cell translocation gene 1, anti-proliferative 2.1674
MYO19 myosin XIX 2.16215
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.16157
TTBK2 tau tubulin kinase 2 2.1603
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.15395
KRT13 keratin 13, type I 2.14945
CHEK2 checkpoint kinase 2 2.14902
ZNF33B zinc finger protein 33B 2.1476
KRT5 keratin 5, type II 2.1461
THAP1 THAP domain containing, apoptosis associated protein 1 2.14215
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.1396
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.13258
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.1306
PRAMEF10 PRAME family member 10 2.12635
UNKL unkempt family zinc finger-like 2.12195
MRPL19 mitochondrial ribosomal protein L19 2.12135
MEF2B myocyte enhancer factor 2B 2.1123
SMAD3 SMAD family member 3 2.11229
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.11048
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.11035
SLC66A3 solute carrier family 66 member 3 2.1084
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.1083
FBXO5 F-box protein 5 2.10505
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.1042
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.10355
PTGFR prostaglandin F receptor (FP) 2.10105
ANKRD10 ankyrin repeat domain 10 2.0997
KLC3 kinesin light chain 3 2.09825
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.09025
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.0861
MYH2 myosin, heavy chain 2, skeletal muscle, adult 2.08605
QPCTL glutaminyl-peptide cyclotransferase-like 2.0827
SWAP70 SWAP switching B-cell complex 70kDa subunit 2.08268
EVA1B eva-1 homolog B (C. elegans) 2.07807
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.07575
LMTK2 lemur tyrosine kinase 2 2.07295
PLD3 phospholipase D family, member 3 2.07275
TEC tec protein tyrosine kinase 2.07225
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.07175
KLHL9 kelch-like family member 9 2.07148
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 2.0686
MAPK12 mitogen-activated protein kinase 12 2.0638
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 2.0631
GFRA3 GDNF family receptor alpha 3 2.0597
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.058
LMF1 lipase maturation factor 1 2.05715
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 2.05705
ZNF257 zinc finger protein 257 2.05455
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.05277
CAVIN2 caveolae associated protein 2 2.0521
CLCN2 chloride channel, voltage-sensitive 2 2.05075
ZNF322 zinc finger protein 322 2.04355
PTK6 protein tyrosine kinase 6 2.042
POU3F3 POU class 3 homeobox 3 2.0419
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.03975
SPAG7 sperm associated antigen 7 2.03815
RUNDC3A RUN domain containing 3A 2.03723
S1PR4 sphingosine-1-phosphate receptor 4 2.0368
FAT2 FAT atypical cadherin 2 2.03615
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.0345
LDHB lactate dehydrogenase B 2.03358
MELK maternal embryonic leucine zipper kinase 2.03315
MATR3 matrin 3 2.03303
KIFBP kinesin family binding protein 2.033
PODXL2 podocalyxin-like 2 2.03245
MPHOSPH9 M-phase phosphoprotein 9 2.03155
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.03122
GCGR glucagon receptor 2.0292
CERS4 ceramide synthase 4 2.02735
DRD4 dopamine receptor D4 2.0273
TCERG1 transcription elongation regulator 1 2.0262
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 2.02387
COL9A1 collagen, type IX, alpha 1 2.021
DGKQ diacylglycerol kinase, theta 110kDa 2.0204
LIPC lipase, hepatic 2.01945
FGF8 fibroblast growth factor 8 (androgen-induced) 2.01915
DST dystonin 2.01684
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 2.0158
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.01385
AMH anti-Mullerian hormone 2.0122
WDCP WD repeat and coiled coil containing 2.0079
SOX10 SRY (sex determining region Y)-box 10 2.0075
PRDM10 PR domain containing 10 2.006
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.00584
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.0048
CREB5 cAMP responsive element binding protein 5 2.0043
CLDN14 claudin 14 2.0043
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.0029
RRAGB Ras-related GTP binding B 2.00075
ANGPTL7 angiopoietin-like 7 2.0007

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -8.71105
FGFR4 fibroblast growth factor receptor 4 -8.18573
TSEN2 TSEN2 tRNA splicing endonuclease subunit -6.67125
COG7 component of oligomeric golgi complex 7 -5.66945
COG2 component of oligomeric golgi complex 2 -5.34915
TUBB6 tubulin, beta 6 class V -5.33285
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -5.27775
LAP3 leucine aminopeptidase 3 -5.26325
TRIB3 tribbles pseudokinase 3 -5.08165
PECR peroxisomal trans-2-enoyl-CoA reductase -5.06935
NGRN neugrin, neurite outgrowth associated -5.0108
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.0
PLK1 polo-like kinase 1 -4.9179
MRPS2 mitochondrial ribosomal protein S2 -4.836
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.7919
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.73475
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.6865
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -4.6315
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.62978
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.56805
CCNB1 cyclin B1 -4.52405
ZDHHC6 zinc finger, DHHC-type containing 6 -4.51885
C2CD5 C2 calcium-dependent domain containing 5 -4.492
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.43985
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.4151
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.387
CHMP4B charged multivesicular body protein 4B -4.30615
NUP85 nucleoporin 85kDa -4.26185
LDHD lactate dehydrogenase D -4.2249
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.01015
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.93835
TCTN1 tectonic family member 1 -3.93505
KDM3A lysine (K)-specific demethylase 3A -3.8789
SLC35F2 solute carrier family 35, member F2 -3.83235
HMG20B high mobility group 20B -3.7325
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.60008
GRWD1 glutamate-rich WD repeat containing 1 -3.5992
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.5769
JMJD6 jumonji domain containing 6 -3.45433
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -3.4517
ADI1 acireductone dioxygenase 1 -3.33375
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -3.3256
SOX9 SRY (sex determining region Y)-box 9 -3.29725
MRPS7 mitochondrial ribosomal protein S7 -3.18745
DPH2 DPH2 homolog (S. cerevisiae) -3.18285
DERA deoxyribose-phosphate aldolase (putative) -3.13285
UBE3C ubiquitin protein ligase E3C -3.1285
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.10535
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.09
PMPCA peptidase (mitochondrial processing) alpha -3.08435
METTL9 methyltransferase like 9 -3.06545
MRPL46 mitochondrial ribosomal protein L46 -3.04695
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.01245
CCNB2 cyclin B2 -2.99015
GNAS GNAS complex locus -2.9899
ARID5B AT rich interactive domain 5B (MRF1-like) -2.9036
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.8798
PPT1 palmitoyl-protein thioesterase 1 -2.8767
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -2.8717
RHEB Ras homolog enriched in brain -2.86843
SEC13 SEC13 homolog (S. cerevisiae) -2.85055
ALOX5AP arachidonate 5-lipoxygenase-activating protein -2.7975
WDR7 WD repeat domain 7 -2.77815
PRPF4 pre-mRNA processing factor 4 -2.77565
TSKU tsukushi, small leucine rich proteoglycan -2.7656
CETN2 centrin, EF-hand protein, 2 -2.7524
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.72382
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -2.7097
RABEPK Rab9 effector protein with kelch motifs -2.687
PDZD2 PDZ domain containing 2 -2.68568
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.68165
CD53 CD53 molecule -2.67455
SLAMF8 SLAM family member 8 -2.63125
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.62425
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.61115
MXRA7 matrix-remodelling associated 7 -2.60545
SAP30BP SAP30 binding protein -2.6035
INTS14 integrator complex subunit 14 -2.5852
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.5806
SNRPC small nuclear ribonucleoprotein polypeptide C -2.57315
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -2.56125
C1QA complement component 1, q subcomponent, A chain -2.54645
NR0B2 nuclear receptor subfamily 0, group B, member 2 -2.54565
TRAP1 TNF receptor-associated protein 1 -2.54145
CERS6 ceramide synthase 6 -2.53872
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.53055
CKLF-CMTM1 CKLF-CMTM1 readthrough -2.5296
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -2.5247
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.50332
LOC124907782 dual specificity protein phosphatase 22 -2.4982
CIAO2B cytosolic iron-sulfur assembly component 2B -2.48915
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.4735
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -2.46835
MYL9 myosin, light chain 9, regulatory -2.465
ZMIZ1 zinc finger, MIZ-type containing 1 -2.46165
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.45905
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -2.4425
TTC38 tetratricopeptide repeat domain 38 -2.4386
SOBP sine oculis binding protein homolog (Drosophila) -2.4369
DYNLT1 dynein, light chain, Tctex-type 1 -2.4023
HLA-DMB major histocompatibility complex, class II, DM beta -2.40155
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.39475
PNPLA6 patatin-like phospholipase domain containing 6 -2.39375
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.38765
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.38747
RNF187 ring finger protein 187 -2.3794
RAB5IF RAB5 interacting factor -2.37785
CD58 CD58 molecule -2.37143
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -2.3707
MKS1 Meckel syndrome, type 1 -2.3696
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.36145
IL2RB interleukin 2 receptor, beta -2.3562
FBXO7 F-box protein 7 -2.3457
NXT1 nuclear transport factor 2-like export factor 1 -2.33615
NELFB negative elongation factor complex member B -2.33015
TMEM268 transmembrane protein 268 -2.3059
SUOX sulfite oxidase -2.2919
IL17RB interleukin 17 receptor B -2.2877
RPIA ribose 5-phosphate isomerase A -2.28535
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.28415
COA3 cytochrome c oxidase assembly factor 3 -2.2838
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.2704
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -2.27013
STX18 syntaxin 18 -2.26545
DSE dermatan sulfate epimerase -2.26
SUMO4 small ubiquitin-like modifier 4 -2.2565
MCM6 minichromosome maintenance complex component 6 -2.25285
MED24 mediator complex subunit 24 -2.2454
WNT5A wingless-type MMTV integration site family, member 5A -2.24342
VCAM1 vascular cell adhesion molecule 1 -2.2398
HYOU1 hypoxia up-regulated 1 -2.23115
CTSA cathepsin A -2.2278
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -2.22465
AOAH acyloxyacyl hydrolase (neutrophil) -2.22465
MRPS10 mitochondrial ribosomal protein S10 -2.21845
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.21093
ACOX3 acyl-CoA oxidase 3, pristanoyl -2.2055
CRLF1 cytokine receptor-like factor 1 -2.19585
IGFLR1 IGF-like family receptor 1 -2.19385
ETV6 ets variant 6 -2.1929
MRPL58 mitochondrial ribosomal protein L58 -2.19045
EIF5 eukaryotic translation initiation factor 5 -2.18758
SRSF2 serine/arginine-rich splicing factor 2 -2.18698
GAK cyclin G associated kinase -2.18445
BLMH bleomycin hydrolase -2.18395
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.1818
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.17365
ASL argininosuccinate lyase -2.1734
RXRA retinoid X receptor, alpha -2.16692
CRTC3 CREB regulated transcription coactivator 3 -2.1639
RNASE6 ribonuclease, RNase A family, k6 -2.157
STK25 serine/threonine kinase 25 -2.15185
TGFBI transforming growth factor, beta-induced, 68kDa -2.14825
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.1406
HLA-DMA major histocompatibility complex, class II, DM alpha -2.1369
ITGB1BP1 integrin beta 1 binding protein 1 -2.13075
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.12188
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.1187
PLXNB2 plexin B2 -2.1186
SEC16A SEC16 homolog A (S. cerevisiae) -2.11205
RFC2 replication factor C (activator 1) 2, 40kDa -2.1113
BRD3 bromodomain containing 3 -2.10168
TBCB tubulin folding cofactor B -2.0921
RGS2 regulator of G-protein signaling 2 -2.0915
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.09135
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.08275
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.07715
CTSC cathepsin C -2.07465
LMAN2L lectin, mannose-binding 2-like -2.0738
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.071
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.0642
PWWP3A PWWP domain containing 3A, DNA repair factor -2.0619
CDA cytidine deaminase -2.05895
AGMAT agmatine ureohydrolase (agmatinase) -2.0539
IL10RB interleukin 10 receptor, beta -2.05325
KL klotho -2.05295
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -2.051
LAMC3 laminin, gamma 3 -2.05035
NOP56 NOP56 ribonucleoprotein -2.04835
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.04795
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -2.04315
FURIN furin (paired basic amino acid cleaving enzyme) -2.0414
FN3KRP fructosamine 3 kinase related protein -2.0396
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.03625
HAPSTR1 HUWE1 associated protein modifying stress responses -2.0323
HIRIP3 HIRA interacting protein 3 -2.03195
BCL7C B-cell CLL/lymphoma 7C -2.0304
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.0272
GPR65 G protein-coupled receptor 65 -2.0197
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.01685
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -2.01503
PANK2 pantothenate kinase 2 -2.01475
PTTG1IP pituitary tumor-transforming 1 interacting protein -2.0114
TMEM184B transmembrane protein 184B -2.0091