| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-vinylpyrrolidone-2 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN011_HEPG2_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.9341 |
| STK10 | serine/threonine kinase 10 | 4.90427 |
| ADRB2 | adrenoceptor beta 2, surface | 4.8606 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.8378 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 4.76292 |
| LCN2 | lipocalin 2 | 4.6941 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.61344 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.36823 |
| HOOK2 | hook microtubule-tethering protein 2 | 4.26905 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.23375 |
| MAP7 | microtubule-associated protein 7 | 4.1478 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.80835 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.77457 |
| TLR4 | toll-like receptor 4 | 3.4504 |
| ATP11B | ATPase, class VI, type 11B | 3.3959 |
| ABHD6 | abhydrolase domain containing 6 | 3.20985 |
| JADE2 | jade family PHD finger 2 | 2.7766 |
| RNF167 | ring finger protein 167 | 2.75205 |
| LOC122526780 | uncharacterized LOC122526780 | 2.7469 |
| PTK2 | protein tyrosine kinase 2 | 2.54982 |
| CHN1 | chimerin 1 | 2.50965 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.50615 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.4735 |
| COQ8A | coenzyme Q8A | 2.35275 |
| GRB10 | growth factor receptor-bound protein 10 | 2.29463 |
| GPATCH8 | G patch domain containing 8 | 2.21195 |
| RBKS | ribokinase | 2.21107 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.17605 |
| NPIPB6 | nuclear pore complex interacting protein family, member B6 | 2.01635 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.00264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -5.25795 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.2005 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| TES | testin LIM domain protein | -3.41145 |
| CCNB2 | cyclin B2 | -3.3263 |
| GNAS | GNAS complex locus | -3.28279 |
| ADI1 | acireductone dioxygenase 1 | -3.2642 |
| HEATR1 | HEAT repeat containing 1 | -3.25003 |
| SLC35F2 | solute carrier family 35, member F2 | -3.1702 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.07483 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.60925 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.59005 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | -2.57135 |
| MVP | major vault protein | -2.44595 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.30335 |
| ZNF586 | zinc finger protein 586 | -2.25925 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.21333 |
| LHX2 | LIM homeobox 2 | -2.19362 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.1901 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -2.09125 |
| CD82 | CD82 molecule | -2.03755 |
