CRCGN011_HEPG2_24H:D13 Gene Set
Genes
60 genes differentially expressed following the CRCGN011_HEPG2_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
8.59093
|
|
RPL39L
|
ribosomal protein L39-like
|
5.86605
|
|
MYLK
|
myosin light chain kinase
|
5.55435
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.3754
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
5.15035
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.0439
|
|
NOTCH1
|
notch 1
|
4.80525
|
|
UBQLN2
|
ubiquilin 2
|
4.75445
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.50865
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.36382
|
|
MAP7
|
microtubule-associated protein 7
|
3.61548
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.56825
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.42622
|
|
COQ8A
|
coenzyme Q8A
|
3.1406
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.0447
|
|
LCN2
|
lipocalin 2
|
2.93975
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.74105
|
|
RNF167
|
ring finger protein 167
|
2.70805
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.55305
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.1909
|
|
USP9X
|
ubiquitin specific peptidase 9, X-linked
|
2.17415
|
|
HNRNPAB
|
heterogeneous nuclear ribonucleoprotein A/B
|
2.13055
|
|
ALG3
|
ALG3, alpha-1,3- mannosyltransferase
|
2.10825
|
|
TPST1
|
tyrosylprotein sulfotransferase 1
|
2.10365
|
|
CFAP20
|
cilia and flagella associated protein 20
|
2.05955
|
|
RER1
|
retention in endoplasmic reticulum sorting receptor 1
|
2.01378
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
-5.4329
|
|
CCDC86
|
coiled-coil domain containing 86
|
-5.0271
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-4.87105
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.7844
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.7386
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.7314
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.43875
|
|
CDC20
|
cell division cycle 20
|
-4.2155
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.17475
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.51577
|
|
GNAS
|
GNAS complex locus
|
-3.45518
|
|
LYPLA1
|
lysophospholipase I
|
-3.22077
|
|
GDF15
|
growth differentiation factor 15
|
-3.1976
|
|
TCTN1
|
tectonic family member 1
|
-3.0556
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.84695
|
|
CDC25B
|
cell division cycle 25B
|
-2.6834
|
|
MRPL15
|
mitochondrial ribosomal protein L15
|
-2.66115
|
|
HOXC8
|
homeobox C8
|
-2.3932
|
|
PNMA8A
|
PNMA family member 8A
|
-2.3393
|
|
JPT2
|
Jupiter microtubule associated homolog 2
|
-2.33512
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.2389
|
|
MAOA
|
monoamine oxidase A
|
-2.14778
|
|
FOXO1
|
forkhead box O1
|
-2.14088
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.09538
|
|
TREM2
|
triggering receptor expressed on myeloid cells 2
|
-2.09295
|
|
PSPC1
|
paraspeckle component 1
|
-2.08685
|
|
LYPLA1-TCEA1
|
LYPLA1-TCEA1 readthrough
|
-2.085
|
|
SLC66A2
|
solute carrier family 66 member 2
|
-2.0794
|
|
S1PR1
|
sphingosine-1-phosphate receptor 1
|
-2.0772
|
|
TMEM258
|
transmembrane protein 258
|
-2.0772
|
|
SUCLA2
|
succinate-CoA ligase, ADP-forming, beta subunit
|
-2.0695
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
-2.06265
|
|
GPN2
|
GPN-loop GTPase 2
|
-2.04355
|
