CRCGN011_HEPG2_24H:D17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description geranyl acetate 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

81 genes differentially expressed following the CRCGN011_HEPG2_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 6.31075
GPATCH8 G patch domain containing 8 5.76335
CYCS cytochrome c, somatic 5.7437
LCN2 lipocalin 2 5.0
CIAO3 cytosolic iron-sulfur assembly component 3 4.97985
PHKG2 phosphorylase kinase, gamma 2 (testis) 4.93605
ATP11B ATPase, class VI, type 11B 4.86125
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.84585
EGF epidermal growth factor 4.8263
E2F2 E2F transcription factor 2 4.71085
PEX11A peroxisomal biogenesis factor 11 alpha 4.63597
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.6242
MYLK myosin light chain kinase 4.62395
STAP2 signal transducing adaptor family member 2 4.0059
SSBP2 single-stranded DNA binding protein 2 3.77947
AMDHD2 amidohydrolase domain containing 2 3.75135
VGLL4 vestigial-like family member 4 3.5784
ABHD4 abhydrolase domain containing 4 3.4692
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.02387
CBR3 carbonyl reductase 3 2.8774
GNG7 guanine nucleotide binding protein (G protein), gamma 7 2.74885
ACBD3 acyl-CoA binding domain containing 3 2.68265
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.6198
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.58735
SMIM5 small integral membrane protein 5 2.43485
SART1 squamous cell carcinoma antigen recognized by T cells 2.4054
KLHL36 kelch-like family member 36 2.3982
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.36475
MAST2 microtubule associated serine/threonine kinase 2 2.35135
HDAC5 histone deacetylase 5 2.3324
CYB561 cytochrome b561 2.26628
RNFT1-DT RNFT1 divergent transcript 2.2487
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.2459
DMRT1 doublesex and mab-3 related transcription factor 1 2.24045
MROH7 maestro heat-like repeat family member 7 2.2321
CAPN5 calpain 5 2.20895
CLMN calmin (calponin-like, transmembrane) 2.20575
P3H3 prolyl 3-hydroxylase 3 2.2002
LGALS4 lectin, galactoside-binding, soluble, 4 2.1707
CEP57 centrosomal protein 57kDa 2.1689
MRPS15 mitochondrial ribosomal protein S15 2.1657
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.1642
ITPKC inositol-trisphosphate 3-kinase C 2.16135
CLCNKA chloride channel, voltage-sensitive Ka 2.14945
UMOD uromodulin 2.1409
PTGFR prostaglandin F receptor (FP) 2.13685
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 2.1347
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 2.1317
HOXD10 homeobox D10 2.11665
NINJ1 ninjurin 1 2.1097
SFRP1 secreted frizzled-related protein 1 2.10187
GAS1 growth arrest-specific 1 2.10135
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.0473
PGAP6 post-GPI attachment to proteins 6 2.0457
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.0233
PLAAT2 phospholipase A and acyltransferase 2 2.01195
MMP10 matrix metallopeptidase 10 2.0

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -5.20885
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.0
COG2 component of oligomeric golgi complex 2 -4.885
GDF15 growth differentiation factor 15 -4.8093
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.8022
CASP3 caspase 3, apoptosis-related cysteine peptidase -4.1522
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.85395
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.84875
GNAS GNAS complex locus -3.39671
CCNB2 cyclin B2 -3.1874
IFT46 intraflagellar transport 46 -2.48955
RAD51C RAD51 paralog C -2.4111
HBE1 hemoglobin, epsilon 1 -2.39155
TNS3 tensin 3 -2.267
CENPE centromere protein E, 312kDa -2.25615
GRWD1 glutamate-rich WD repeat containing 1 -2.20775
AHR aryl hydrocarbon receptor -2.19145
RHOB ras homolog family member B -2.1265
HLA-DMA major histocompatibility complex, class II, DM alpha -2.12135
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.07265
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -2.06665
NDFIP1 Nedd4 family interacting protein 1 -2.05495
SNX11 sorting nexin 11 -2.01165
MAPK1 mitogen-activated protein kinase 1 -2.00392