| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | geranyl acetate 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN011_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.06685 |
| CBR3 | carbonyl reductase 3 | 5.4704 |
| LCN2 | lipocalin 2 | 5.46 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.42695 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.3455 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.8676 |
| STK10 | serine/threonine kinase 10 | 4.85168 |
| STAP2 | signal transducing adaptor family member 2 | 4.2471 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.30365 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.26493 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.15553 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.0578 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | 2.73675 |
| ATP11B | ATPase, class VI, type 11B | 2.71095 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.58955 |
| RAB4A | RAB4A, member RAS oncogene family | 2.58707 |
| ABHD4 | abhydrolase domain containing 4 | 2.5165 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.49155 |
| NOSIP | nitric oxide synthase interacting protein | 2.46035 |
| BAX | BCL2-associated X protein | 2.25305 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | 2.2253 |
| SMAD3 | SMAD family member 3 | 2.1978 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.14902 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.10612 |
| SEC61G | Sec61 gamma subunit | 2.0722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -4.9288 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.5321 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.36215 |
| CCNB2 | cyclin B2 | -3.2754 |
| GNAS | GNAS complex locus | -3.19981 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.01937 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.9519 |
| CDC25B | cell division cycle 25B | -2.93755 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.776 |
| TLCD3A | TLC domain containing 3A | -2.6786 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.5815 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.4262 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.4226 |
| ADI1 | acireductone dioxygenase 1 | -2.3906 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -2.3737 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | -2.25787 |
| TTC21B | tetratricopeptide repeat domain 21B | -2.20605 |
| SLC35F2 | solute carrier family 35, member F2 | -2.1933 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -2.12395 |
| CCKBR | cholecystokinin B receptor | -2.1212 |
| QTRT2 | queuine tRNA-ribosyltransferase accessory subunit 2 | -2.1041 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -2.0959 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 | -2.0807 |
| CLDN18 | claudin 18 | -2.06883 |
| ACRV1 | acrosomal vesicle protein 1 | -2.05718 |
| TM4SF5 | transmembrane 4 L six family member 5 | -2.05285 |
| OR1A1 | olfactory receptor, family 1, subfamily A, member 1 | -2.0431 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 | -2.0385 |
| RIMBP2 | RIMS binding protein 2 | -2.0339 |
