| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | trans-cinnamaldehyde 40.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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134 genes differentially expressed following the CRCGN011_HEPG2_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 6.42623 |
| CHMP6 | charged multivesicular body protein 6 | 5.5918 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 5.47595 |
| NGRN | neugrin, neurite outgrowth associated | 5.36205 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.08185 |
| NOTCH1 | notch 1 | 4.5729 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.5111 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.42795 |
| CYCS | cytochrome c, somatic | 4.2869 |
| MAP7 | microtubule-associated protein 7 | 4.21607 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.49355 |
| HMOX1 | heme oxygenase 1 | 3.315 |
| PRKCH | protein kinase C, eta | 3.0551 |
| CHEK2 | checkpoint kinase 2 | 2.98203 |
| GPATCH8 | G patch domain containing 8 | 2.95072 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.87407 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 2.78305 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.7431 |
| CHN1 | chimerin 1 | 2.6678 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.55 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 2.53585 |
| PLSCR3 | phospholipid scramblase 3 | 2.45445 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 2.4246 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 2.3727 |
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 2.33216 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.26685 |
| TBXA2R | thromboxane A2 receptor | 2.25901 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 2.258 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.25478 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | 2.23975 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | 2.237 |
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial | 2.19605 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 2.17085 |
| TRIM37 | tripartite motif containing 37 | 2.167 |
| DCXR | dicarbonyl/L-xylulose reductase | 2.16365 |
| TTC38 | tetratricopeptide repeat domain 38 | 2.16195 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.1588 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.1486 |
| FSCN1 | fascin actin-bundling protein 1 | 2.1335 |
| TET3 | tet methylcytosine dioxygenase 3 | 2.13105 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 2.12615 |
| GGCT | gamma-glutamylcyclotransferase | 2.12495 |
| IL1R2 | interleukin 1 receptor, type II | 2.12183 |
| ACO2 | aconitase 2, mitochondrial | 2.1187 |
| NOSIP | nitric oxide synthase interacting protein | 2.1095 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.09665 |
| LRRC59 | leucine rich repeat containing 59 | 2.0889 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 2.0734 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 | 2.0688 |
| LCN2 | lipocalin 2 | 2.0589 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 2.0495 |
| KLK12 | kallikrein-related peptidase 12 | 2.0471 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.0175 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.00995 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 2.0067 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| GNAS | GNAS complex locus | -7.16271 |
| TLCD3A | TLC domain containing 3A | -6.6041 |
| COG7 | component of oligomeric golgi complex 7 | -5.33725 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.2304 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.89725 |
| CDC20 | cell division cycle 20 | -4.66275 |
| VAT1 | vesicle amine transport 1 | -4.51375 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.83513 |
| CDC25B | cell division cycle 25B | -3.3604 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.21735 |
| LPAR4 | lysophosphatidic acid receptor 4 | -3.1083 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.096 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.03347 |
| SLITRK3 | SLIT and NTRK-like family, member 3 | -3.009 |
| PCNA | proliferating cell nuclear antigen | -2.97195 |
| LYPLA1 | lysophospholipase I | -2.83343 |
| STON1 | stonin 1 | -2.7573 |
| DPT | dermatopontin | -2.65507 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.63158 |
| TRIM23 | tripartite motif containing 23 | -2.58588 |
| KRT7 | keratin 7, type II | -2.52765 |
| DDX25 | DEAD (Asp-Glu-Ala-Asp) box helicase 25 | -2.47605 |
| NLGN1 | neuroligin 1 | -2.451 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | -2.4447 |
| DOCK3 | dedicator of cytokinesis 3 | -2.43525 |
| ZNF334 | zinc finger protein 334 | -2.4148 |
| SNTG1 | syntrophin, gamma 1 | -2.4137 |
| FOCAD | focadhesin | -2.3773 |
| CNMD | chondromodulin | -2.35515 |
| VDAC1 | voltage-dependent anion channel 1 | -2.35477 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -2.342 |
| BTBD8 | BTB (POZ) domain containing 8 | -2.337 |
| ASTN1 | astrotactin 1 | -2.3261 |
| FGF14 | fibroblast growth factor 14 | -2.3217 |
| PDPN | podoplanin | -2.29822 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -2.2893 |
| PCDH8 | protocadherin 8 | -2.2843 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -2.27075 |
| KCNIP1 | Kv channel interacting protein 1 | -2.2578 |
| ADAMTSL3 | ADAMTS-like 3 | -2.256 |
| CCDC181 | coiled-coil domain containing 181 | -2.25135 |
| FAM110B | family with sequence similarity 110, member B | -2.23255 |
| CMA1 | chymase 1, mast cell | -2.23075 |
| LYPLA1-TCEA1 | LYPLA1-TCEA1 readthrough | -2.22985 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 | -2.22305 |
| ZNF136 | zinc finger protein 136 | -2.21795 |
| SCG3 | secretogranin III | -2.21325 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.2089 |
| IFT70A | intraflagellar transport 70A | -2.1637 |
| XPC | xeroderma pigmentosum, complementation group C | -2.1629 |
| ZNF571 | zinc finger protein 571 | -2.15985 |
| LRRC40 | leucine rich repeat containing 40 | -2.15305 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -2.152 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -2.14995 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -2.14595 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 | -2.1452 |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 | -2.1436 |
| WDR19 | WD repeat domain 19 | -2.13975 |
| SIX6 | SIX homeobox 6 | -2.13185 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.1236 |
| ZNF415 | zinc finger protein 415 | -2.1213 |
| RAB28 | RAB28, member RAS oncogene family | -2.10978 |
| RINT1 | RAD50 interactor 1 | -2.1096 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | -2.10685 |
| TSPAN2 | tetraspanin 2 | -2.1035 |
| SMYD5 | SMYD family member 5 | -2.09585 |
| RIT2 | Ras-like without CAAX 2 | -2.082 |
| KERA | keratocan | -2.08185 |
| ZNF706 | zinc finger protein 706 | -2.0666 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.06365 |
| YBX1 | Y box binding protein 1 | -2.04698 |
| CPVL | carboxypeptidase, vitellogenic-like | -2.028 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -2.02005 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -2.01575 |
| MTMR6 | myotubularin related protein 6 | -2.0094 |
| TRAM1 | translocation associated membrane protein 1 | -2.00787 |
| ZNF302 | zinc finger protein 302 | -2.0074 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | -2.00217 |
