CRCGN011_HEPG2_24H:D20 Gene Set
Genes
51 genes differentially expressed following the CRCGN011_HEPG2_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
10.0
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.63675
|
|
EPHB2
|
EPH receptor B2
|
5.08883
|
|
MYLK
|
myosin light chain kinase
|
5.035
|
|
UBQLN2
|
ubiquilin 2
|
4.69185
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.55305
|
|
HEBP1
|
heme binding protein 1
|
3.4551
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.33415
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.0197
|
|
NMU
|
neuromedin U
|
2.89525
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.6311
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.5785
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.57785
|
|
CYB561
|
cytochrome b561
|
2.29967
|
|
GNE
|
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
|
2.2968
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.29195
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.24935
|
|
GBP1
|
guanylate binding protein 1, interferon-inducible
|
2.23675
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.18655
|
|
RNF167
|
ring finger protein 167
|
2.1835
|
|
FLNC
|
filamin C, gamma
|
2.1607
|
|
TEX10
|
testis expressed 10
|
2.0651
|
|
RHBG
|
Rh family, B glycoprotein (gene/pseudogene)
|
2.06505
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.04695
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
TLCD3A
|
TLC domain containing 3A
|
-8.492
|
|
DSG2
|
desmoglein 2
|
-8.03215
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.47795
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.15185
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.07625
|
|
CDC20
|
cell division cycle 20
|
-4.66275
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.23015
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.48542
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.3333
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.2903
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.21825
|
|
GNAS
|
GNAS complex locus
|
-3.14164
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.8998
|
|
OMG
|
oligodendrocyte myelin glycoprotein
|
-2.81985
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.78705
|
|
HPGD
|
hydroxyprostaglandin dehydrogenase 15-(NAD)
|
-2.77925
|
|
TAF5L
|
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
|
-2.52905
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.49755
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.4106
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.3823
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.24432
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.09395
|
|
SIGLEC15
|
sialic acid binding Ig-like lectin 15
|
-2.05325
|
|
OVGP1
|
oviductal glycoprotein 1, 120kDa
|
-2.03645
|
|
CLDN18
|
claudin 18
|
-2.01865
|
|
NDRG4
|
NDRG family member 4
|
-2.0055
|
