CRCGN011_HEPG2_24H:D22 Gene Set
Genes
47 genes differentially expressed following the CRCGN011_HEPG2_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
6.8889
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
6.4312
|
|
MYLK
|
myosin light chain kinase
|
5.0754
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.7213
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.65835
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.0782
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.73245
|
|
CYCS
|
cytochrome c, somatic
|
3.42895
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.4261
|
|
TLR4
|
toll-like receptor 4
|
3.25705
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.2411
|
|
FPGS
|
folylpolyglutamate synthase
|
2.62025
|
|
CENPS-CORT
|
CENPS-CORT readthrough
|
2.5377
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.50475
|
|
CHN1
|
chimerin 1
|
2.4563
|
|
STK10
|
serine/threonine kinase 10
|
2.35313
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.3511
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.32292
|
|
DNASE1L3
|
deoxyribonuclease I-like 3
|
2.25065
|
|
ELP5
|
elongator acetyltransferase complex subunit 5
|
2.22325
|
|
SATB1
|
SATB homeobox 1
|
2.15695
|
|
NPY1R
|
neuropeptide Y receptor Y1
|
2.12865
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.0852
|
|
IL18RAP
|
interleukin 18 receptor accessory protein
|
2.0301
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-10.0
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-5.31155
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-5.0
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.92525
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.76335
|
|
USP6NL
|
USP6 N-terminal like
|
-4.73085
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.6928
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.23685
|
|
HMG20B
|
high mobility group 20B
|
-4.00305
|
|
GNAS
|
GNAS complex locus
|
-3.63085
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.29285
|
|
DAGLA
|
diacylglycerol lipase, alpha
|
-2.81415
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.6461
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.46548
|
|
TUBA3C
|
tubulin, alpha 3c
|
-2.32005
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.29393
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.2071
|
|
RPS8
|
ribosomal protein S8
|
-2.12435
|
|
LOC128966601
|
pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like
|
-2.087
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.06272
|
|
GRAMD1B
|
GRAM domain containing 1B
|
-2.0235
|
|
CCNH
|
cyclin H
|
-2.0223
|
|
RLIM
|
ring finger protein, LIM domain interacting
|
-2.0135
|
