CRCGN011_HEPG2_24H:D23 Gene Set
Genes
46 genes differentially expressed following the CRCGN011_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.795
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
5.64865
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.48305
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
5.13425
|
|
MYLK
|
myosin light chain kinase
|
5.05375
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.56495
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.00615
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.96392
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.54235
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.49405
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
3.38145
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.96443
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.9152
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.4925
|
|
FOXJ3
|
forkhead box J3
|
2.42878
|
|
TBP
|
TATA box binding protein
|
2.403
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.26955
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
2.15815
|
|
INTS3
|
integrator complex subunit 3
|
2.1056
|
|
WNT11
|
wingless-type MMTV integration site family, member 11
|
2.07105
|
|
SMAD3
|
SMAD family member 3
|
2.038
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.41035
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.28935
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.12045
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.0845
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.0
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-4.99305
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.94015
|
|
GOLT1B
|
golgi transport 1B
|
-4.59255
|
|
CDC25B
|
cell division cycle 25B
|
-4.06285
|
|
TWF2
|
twinfilin actin binding protein 2
|
-4.04065
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.91635
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.55614
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.42665
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.36825
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-3.05233
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.99362
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.80333
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.75495
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.44025
|
|
WDR7
|
WD repeat domain 7
|
-2.3614
|
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa
|
-2.3134
|
|
LAMP5
|
lysosomal-associated membrane protein family, member 5
|
-2.27155
|
|
AURKA
|
aurora kinase A
|
-2.18407
|
|
CCNB2
|
cyclin B2
|
-2.096
|
|
NSF
|
N-ethylmaleimide-sensitive factor
|
-2.09585
|
