| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-amino-3-oxo-3h-phenoxazine-1,9-dicarboxylic acid 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN011_HEPG2_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 6.44215 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.6549 |
| MAMLD1 | mastermind-like domain containing 1 | 5.04915 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 4.8715 |
| UBQLN2 | ubiquilin 2 | 4.30415 |
| IDE | insulin-degrading enzyme | 4.26365 |
| STIMATE | STIM activating enhancer | 3.84755 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.81455 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.7757 |
| CYCS | cytochrome c, somatic | 3.7275 |
| HMOX1 | heme oxygenase 1 | 3.0075 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.9884 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.7228 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2.71585 |
| FASTKD5 | FAST kinase domains 5 | 2.6345 |
| EVL | Enah/Vasp-like | 2.53615 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 2.44305 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.42345 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2.29205 |
| HEBP1 | heme binding protein 1 | 2.25175 |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa | 2.22735 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.2056 |
| TPD52L2 | tumor protein D52-like 2 | 2.1833 |
| DCTN6 | dynactin 6 | 2.15615 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 2.14205 |
| PLSCR3 | phospholipid scramblase 3 | 2.05503 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 2.02765 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 2.02235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPK13 | mitogen-activated protein kinase 13 | -6.20957 |
| CDC20 | cell division cycle 20 | -5.31545 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.1593 |
| DNM1L | dynamin 1-like | -4.96385 |
| RPN1 | ribophorin I | -4.81435 |
| CHMP4B | charged multivesicular body protein 4B | -4.76373 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.6745 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.52715 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.50055 |
| GDF15 | growth differentiation factor 15 | -4.4727 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.13625 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.4659 |
| SPAG4 | sperm associated antigen 4 | -3.39105 |
| GNAS | GNAS complex locus | -3.33604 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.12935 |
| PCNA | proliferating cell nuclear antigen | -2.86435 |
| TLCD3A | TLC domain containing 3A | -2.83625 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.62045 |
| CCNB2 | cyclin B2 | -2.58225 |
| PPT1 | palmitoyl-protein thioesterase 1 | -2.4554 |
| DCK | deoxycytidine kinase | -2.3264 |
| TRAPPC14 | trafficking protein particle complex subunit 14 | -2.3224 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.26939 |
| MUC13 | mucin 13, cell surface associated | -2.22525 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -2.2001 |
| ZNF813 | zinc finger protein 813 | -2.18575 |
| FMNL1 | formin-like 1 | -2.17805 |
| MUTYH | mutY homolog | -2.1584 |
| ZC3H4 | zinc finger CCCH-type containing 4 | -2.14085 |
| RNF167 | ring finger protein 167 | -2.1318 |
| BPGM | 2,3-bisphosphoglycerate mutase | -2.1002 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -2.093 |
| DAD1 | defender against cell death 1 | -2.0913 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -2.08055 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -2.0768 |
| GPR162 | G protein-coupled receptor 162 | -2.056 |
| ZNF274 | zinc finger protein 274 | -2.04565 |
| BDKRB1 | bradykinin receptor B1 | -2.0188 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -2.00045 |
