| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-amino-3-oxo-3h-phenoxazine-1,9-dicarboxylic acid 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN011_HEPG2_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.71035 |
| LOC122526780 | uncharacterized LOC122526780 | 5.65885 |
| GPATCH8 | G patch domain containing 8 | 5.44833 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.1438 |
| MYLK | myosin light chain kinase | 4.89645 |
| UBQLN2 | ubiquilin 2 | 4.88905 |
| CBR3 | carbonyl reductase 3 | 4.86875 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.8305 |
| RPL39L | ribosomal protein L39-like | 4.8238 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.05465 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.0487 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.00955 |
| EPHA3 | EPH receptor A3 | 3.65983 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.59153 |
| CHEK2 | checkpoint kinase 2 | 3.543 |
| MAP7 | microtubule-associated protein 7 | 3.46833 |
| TLR4 | toll-like receptor 4 | 3.4018 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.12785 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.77737 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.7555 |
| MMP2 | matrix metallopeptidase 2 | 2.72725 |
| WASF3 | WAS protein family, member 3 | 2.5121 |
| GATA2 | GATA binding protein 2 | 2.41375 |
| CYB561 | cytochrome b561 | 2.338 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 2.3198 |
| HMOX1 | heme oxygenase 1 | 2.28795 |
| CCNF | cyclin F | 2.24618 |
| PRR15L | proline rich 15-like | 2.22055 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | 2.1593 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 2.1035 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 2.066 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 2.02865 |
| TESK1 | testis-specific kinase 1 | 2.0264 |
| UIMC1 | ubiquitin interaction motif containing 1 | 2.02355 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 2.01224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FASTKD5 | FAST kinase domains 5 | -5.21675 |
| CD320 | CD320 molecule | -5.1872 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.8834 |
| CCNB2 | cyclin B2 | -4.5448 |
| CDC20 | cell division cycle 20 | -4.2518 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.762 |
| TOR1A | torsin family 1, member A (torsin A) | -3.25537 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.79817 |
| SNIP1 | Smad nuclear interacting protein 1 | -2.69635 |
| PCNA | proliferating cell nuclear antigen | -2.6794 |
| GDF15 | growth differentiation factor 15 | -2.5912 |
| TMEM38B | transmembrane protein 38B | -2.49735 |
| NGRN | neugrin, neurite outgrowth associated | -2.4902 |
| CRY2 | cryptochrome circadian clock 2 | -2.43 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.34572 |
| HEATR1 | HEAT repeat containing 1 | -2.32835 |
| BAG2 | BCL2-associated athanogene 2 | -2.20295 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.19795 |
| NRBF2 | nuclear receptor binding factor 2 | -2.17545 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 | -2.15895 |
| CD8A | CD8a molecule | -2.1501 |
| AIRE | autoimmune regulator | -2.14825 |
| MT1E | metallothionein 1E | -2.13795 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.13215 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.1131 |
| NKG7 | natural killer cell granule protein 7 | -2.10275 |
| INTS5 | integrator complex subunit 5 | -2.083 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | -2.06805 |
| GCAT | glycine C-acetyltransferase | -2.00968 |
| PRPF4 | pre-mRNA processing factor 4 | -2.00152 |
