| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibutyltin diacetate 10.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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113 genes differentially expressed following the CRCGN011_HEPG2_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 7.9203 |
| RPL39L | ribosomal protein L39-like | 5.54935 |
| UBQLN2 | ubiquilin 2 | 5.3091 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.19145 |
| E2F2 | E2F transcription factor 2 | 5.1168 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 5.10065 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.8487 |
| CSK | c-src tyrosine kinase | 4.66275 |
| ADRB2 | adrenoceptor beta 2, surface | 4.6298 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.9942 |
| NMU | neuromedin U | 3.9561 |
| HEBP1 | heme binding protein 1 | 3.7488 |
| PIH1D1 | PIH1 domain containing 1 | 3.4702 |
| CHN1 | chimerin 1 | 3.43735 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.01205 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2.929 |
| TRAM2 | translocation associated membrane protein 2 | 2.9087 |
| MBD5 | methyl-CpG binding domain protein 5 | 2.8803 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 2.7445 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.71855 |
| HSPA1A | heat shock 70kDa protein 1A | 2.69715 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.6836 |
| LAMP3 | lysosomal-associated membrane protein 3 | 2.66545 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.65805 |
| RAB31 | RAB31, member RAS oncogene family | 2.56158 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 2.50955 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.47397 |
| H2BC12 | H2B clustered histone 12 | 2.38793 |
| OAZ2 | ornithine decarboxylase antizyme 2 | 2.36855 |
| SPAG16 | sperm associated antigen 16 | 2.36435 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.32655 |
| EPHA3 | EPH receptor A3 | 2.25785 |
| CBR1 | carbonyl reductase 1 | 2.25445 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 2.25045 |
| EMC3 | ER membrane protein complex subunit 3 | 2.23775 |
| NFE2 | nuclear factor, erythroid 2 | 2.2326 |
| CH25H | cholesterol 25-hydroxylase | 2.21415 |
| HPN | hepsin | 2.2076 |
| LTA4H | leukotriene A4 hydrolase | 2.20615 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | 2.19977 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 2.15585 |
| IFT57 | intraflagellar transport 57 | 2.1451 |
| UNC13B | unc-13 homolog B (C. elegans) | 2.1368 |
| PPL | periplakin | 2.1259 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 2.11875 |
| ANOS1 | anosmin 1 | 2.118 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 2.1179 |
| TCF12 | transcription factor 12 | 2.1144 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 2.11092 |
| GPATCH8 | G patch domain containing 8 | 2.10623 |
| TUSC3 | tumor suppressor candidate 3 | 2.09763 |
| EMP2 | epithelial membrane protein 2 | 2.0939 |
| STX4 | syntaxin 4 | 2.09335 |
| THAP10 | THAP domain containing 10 | 2.083 |
| JHY | junctional cadherin complex regulator | 2.07095 |
| OR51E2 | olfactory receptor, family 51, subfamily E, member 2 | 2.068 |
| PGPEP1 | pyroglutamyl-peptidase I | 2.04025 |
| ABHD4 | abhydrolase domain containing 4 | 2.02265 |
| VEGFD | vascular endothelial growth factor D | 2.00765 |
| ANKRD10 | ankyrin repeat domain 10 | 2.00745 |
| TDRD1 | tudor domain containing 1 | 2.0016 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C | 2.00065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| PCNA | proliferating cell nuclear antigen | -9.2192 |
| SLC35F2 | solute carrier family 35, member F2 | -6.9558 |
| DNM1L | dynamin 1-like | -6.04185 |
| TLCD3A | TLC domain containing 3A | -4.889 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.71785 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.26905 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -4.04005 |
| INPP1 | inositol polyphosphate-1-phosphatase | -3.7541 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.74345 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.70775 |
| IER3 | immediate early response 3 | -3.3099 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.8605 |
| DUSP6 | dual specificity phosphatase 6 | -2.85847 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.85388 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.7407 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -2.7184 |
| CSNK1E | casein kinase 1, epsilon | -2.59795 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -2.59448 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.57225 |
| GPR137B | G protein-coupled receptor 137B | -2.56435 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.55118 |
| LIF | leukemia inhibitory factor | -2.5419 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.4899 |
| EPS8L3 | EPS8-like 3 | -2.45435 |
| ACOT9 | acyl-CoA thioesterase 9 | -2.4114 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | -2.384 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -2.3839 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -2.3135 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -2.3034 |
| EGR1 | early growth response 1 | -2.28288 |
| RBM15B | RNA binding motif protein 15B | -2.2544 |
| TSPOAP1 | TSPO associated protein 1 | -2.22435 |
| TUBB6 | tubulin, beta 6 class V | -2.19605 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -2.17033 |
| TBC1D31 | TBC1 domain family, member 31 | -2.16675 |
| GBA1 | glucosylceramidase beta 1 | -2.1441 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.14365 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -2.1388 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -2.11865 |
| HEATR1 | HEAT repeat containing 1 | -2.1182 |
| CNN1 | calponin 1, basic, smooth muscle | -2.10175 |
| KIF14 | kinesin family member 14 | -2.1016 |
| SQOR | sulfide quinone oxidoreductase | -2.0968 |
| TSPAN4 | tetraspanin 4 | -2.08395 |
| THBS4 | thrombospondin 4 | -2.06915 |
| CHEK1 | checkpoint kinase 1 | -2.0223 |
| MAPK12 | mitogen-activated protein kinase 12 | -2.01635 |
| MUC13 | mucin 13, cell surface associated | -2.00885 |
| MTMR11 | myotubularin related protein 11 | -2.0038 |
| CAB39 | calcium binding protein 39 | -2.0017 |
