CRCGN011_HEPG2_24H:E13 Gene Set
Genes
50 genes differentially expressed following the CRCGN011_HEPG2_24H:E13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.3966
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.0713
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.9289
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.82805
|
|
CSK
|
c-src tyrosine kinase
|
4.66275
|
|
UBQLN2
|
ubiquilin 2
|
4.5876
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.43677
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
4.24255
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.05235
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.90845
|
|
KIF5C
|
kinesin family member 5C
|
3.61398
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.3548
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.2977
|
|
GATA3
|
GATA binding protein 3
|
3.177
|
|
ZNF589
|
zinc finger protein 589
|
3.15122
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.673
|
|
RAI14
|
retinoic acid induced 14
|
2.6192
|
|
NEFL
|
neurofilament, light polypeptide
|
2.55997
|
|
AK5
|
adenylate kinase 5
|
2.46855
|
|
CHEK2
|
checkpoint kinase 2
|
2.4212
|
|
CHN1
|
chimerin 1
|
2.3633
|
|
PIGN
|
phosphatidylinositol glycan anchor biosynthesis, class N
|
2.17935
|
|
MAGT1
|
magnesium transporter 1
|
2.16435
|
|
GATA2
|
GATA binding protein 2
|
2.15007
|
|
PLEKHA2
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
|
2.1483
|
|
GALNT11
|
polypeptide N-acetylgalactosaminyltransferase 11
|
2.1221
|
|
GREB1L
|
growth regulation by estrogen in breast cancer-like
|
2.0469
|
|
SLC17A6
|
solute carrier family 17 (vesicular glutamate transporter), member 6
|
2.01325
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.3433
|
|
THAP11
|
THAP domain containing 11
|
-5.149
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-5.14835
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.0
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.98025
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.9047
|
|
CCNB2
|
cyclin B2
|
-4.6192
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-4.13975
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.74115
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.50653
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.31897
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.83915
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.711
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.49035
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.45915
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.25583
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.19925
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.16005
|
|
SCARA3
|
scavenger receptor class A, member 3
|
-2.1303
|
|
CASZ1
|
castor zinc finger 1
|
-2.0771
|
|
MVP
|
major vault protein
|
-2.05885
|
