| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazine sulfate 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
71 genes differentially expressed following the CRCGN011_HEPG2_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CSK | c-src tyrosine kinase | 5.523 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.52225 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.2492 |
| UBQLN2 | ubiquilin 2 | 5.06835 |
| PLS1 | plastin 1 | 4.87085 |
| RPL39L | ribosomal protein L39-like | 4.766 |
| MOK | MOK protein kinase | 4.5073 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.3336 |
| MELK | maternal embryonic leucine zipper kinase | 3.9154 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.61035 |
| MAP7 | microtubule-associated protein 7 | 3.59798 |
| TLR4 | toll-like receptor 4 | 3.53015 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.5063 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.35015 |
| PRKCH | protein kinase C, eta | 3.21282 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.01 |
| COQ8A | coenzyme Q8A | 2.9469 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.79007 |
| JADE2 | jade family PHD finger 2 | 2.75885 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.7302 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.71595 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.69738 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.68255 |
| GRB10 | growth factor receptor-bound protein 10 | 2.62472 |
| AMACR | alpha-methylacyl-CoA racemase | 2.45938 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | 2.43795 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 2.3881 |
| GPATCH8 | G patch domain containing 8 | 2.38365 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | 2.22625 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.225 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 2.15755 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.11905 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 2.10945 |
| LPXN | leupaxin | 2.083 |
| CSF1R | colony stimulating factor 1 receptor | 2.07265 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.04785 |
| TMEM187 | transmembrane protein 187 | 2.0131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -9.65375 |
| USP6NL | USP6 N-terminal like | -6.272 |
| TRIB3 | tribbles pseudokinase 3 | -5.22595 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.9237 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.8366 |
| DUSP6 | dual specificity phosphatase 6 | -4.49973 |
| HMG20B | high mobility group 20B | -3.87325 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.8145 |
| GNAS | GNAS complex locus | -3.65397 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -3.65205 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.65055 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.47135 |
| RGS2 | regulator of G-protein signaling 2 | -3.42425 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.27748 |
| PCNA | proliferating cell nuclear antigen | -3.0955 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.02152 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -2.7905 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.6311 |
| CCNB2 | cyclin B2 | -2.40625 |
| WASHC4 | WASH complex subunit 4 | -2.35007 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.3461 |
| ADRM1 | adhesion regulating molecule 1 | -2.2947 |
| TLCD3A | TLC domain containing 3A | -2.28795 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 | -2.28253 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.2273 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.21585 |
| SETD1B | SET domain containing 1B | -2.14085 |
| HLA-G | major histocompatibility complex, class I, G | -2.13497 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.1109 |
| CORO2B | coronin, actin binding protein, 2B | -2.10495 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -2.0917 |
| ZNF112 | zinc finger protein 112 | -2.09035 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -2.0084 |
