| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosodiethylamine 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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85 genes differentially expressed following the CRCGN011_HEPG2_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STIMATE | STIM activating enhancer | 9.3954 |
| INTS3 | integrator complex subunit 3 | 6.15925 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.35425 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.33205 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.2575 |
| KLHL9 | kelch-like family member 9 | 5.16183 |
| TBC1D10C | TBC1 domain family, member 10C | 5.0421 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.92595 |
| CCNF | cyclin F | 4.90457 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.75565 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.6297 |
| LCN2 | lipocalin 2 | 4.60305 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.0847 |
| PFKL | phosphofructokinase, liver | 3.52525 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 3.41835 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.2798 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.702 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 2.6261 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 2.62445 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 2.55165 |
| CHEK2 | checkpoint kinase 2 | 2.5498 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.5478 |
| ABHD4 | abhydrolase domain containing 4 | 2.4614 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.43642 |
| HSPA14 | heat shock 70kDa protein 14 | 2.4199 |
| UBTF | upstream binding transcription factor, RNA polymerase I | 2.33878 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.25785 |
| MCMBP | minichromosome maintenance complex binding protein | 2.24295 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | 2.1568 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 2.1566 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 2.1335 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | 2.115 |
| LYRM4 | LYR motif containing 4 | 2.10845 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.0981 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | 2.0873 |
| FAM171A1 | family with sequence similarity 171, member A1 | 2.05695 |
| DCLRE1A | DNA cross-link repair 1A | 2.04985 |
| HSPA1B | heat shock 70kDa protein 1B | 2.04393 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor | 2.04195 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 2.0271 |
| NECTIN2 | nectin cell adhesion molecule 2 | 2.02185 |
| DNM2 | dynamin 2 | 2.01225 |
| ERCC1 | excision repair cross-complementation group 1 | 2.00557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| VAT1 | vesicle amine transport 1 | -10.0 |
| DERA | deoxyribose-phosphate aldolase (putative) | -5.7056 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.23075 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.71785 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.3367 |
| EIF5 | eukaryotic translation initiation factor 5 | -4.20187 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.66595 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.483 |
| GNAS | GNAS complex locus | -3.4156 |
| ZW10 | zw10 kinetochore protein | -3.3931 |
| CCNB2 | cyclin B2 | -3.3817 |
| WASHC4 | WASH complex subunit 4 | -3.31157 |
| CDC25B | cell division cycle 25B | -3.07945 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.854 |
| CAB39 | calcium binding protein 39 | -2.70825 |
| DOCK4 | dedicator of cytokinesis 4 | -2.6971 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.62755 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.6263 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.5131 |
| FAM117A | family with sequence similarity 117, member A | -2.5081 |
| SDF2 | stromal cell-derived factor 2 | -2.4471 |
| CRLF3 | cytokine receptor-like factor 3 | -2.4368 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -2.4204 |
| C5 | complement component 5 | -2.3963 |
| PLIN2 | perilipin 2 | -2.37905 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.36395 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -2.3371 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -2.33705 |
| LIN28A | lin-28 homolog A (C. elegans) | -2.32825 |
| MAT2B | methionine adenosyltransferase II, beta | -2.2618 |
| NFE2 | nuclear factor, erythroid 2 | -2.1558 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | -2.10445 |
| ZNF586 | zinc finger protein 586 | -2.10305 |
| LRRN3 | leucine rich repeat neuronal 3 | -2.10278 |
| CAVIN3 | caveolae associated protein 3 | -2.0989 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -2.0942 |
| ADA2 | adenosine deaminase 2 | -2.0815 |
| MT1G | metallothionein 1G | -2.0696 |
| DPPA4 | developmental pluripotency associated 4 | -2.065 |
| IL10RA | interleukin 10 receptor, alpha | -2.04475 |
| CNGB3 | cyclic nucleotide gated channel beta 3 | -2.0379 |
