CRCGN011_HEPG2_24H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dichloroacetic-acid 10.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

972 genes differentially expressed following the CRCGN011_HEPG2_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HLA-DMA major histocompatibility complex, class II, DM alpha 10.0
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 10.0
MYLK myosin light chain kinase 10.0
NANOS3 nanos homolog 3 (Drosophila) 10.0
CXCL2 chemokine (C-X-C motif) ligand 2 10.0
RPL39L ribosomal protein L39-like 10.0
NOTCH1 notch 1 10.0
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 9.1958
ARL4C ADP-ribosylation factor-like 4C 8.64353
MAP7 microtubule-associated protein 7 8.43287
SNAP25 synaptosomal-associated protein, 25kDa 7.57645
VAV3 vav 3 guanine nucleotide exchange factor 7.2011
TBP TATA box binding protein 6.8117
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 6.79625
KIFBP kinesin family binding protein 6.3614
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 6.3469
SSBP2 single-stranded DNA binding protein 2 6.34285
JADE2 jade family PHD finger 2 5.83415
CBR1 carbonyl reductase 1 5.7439
SOCS2 suppressor of cytokine signaling 2 5.6668
CCNF cyclin F 5.41765
MTERF3 mitochondrial transcription termination factor 3 5.2786
FASTKD5 FAST kinase domains 5 5.1767
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.9127
TRAM2 translocation associated membrane protein 2 4.80185
CYCS cytochrome c, somatic 4.776
PLEKHJ1 pleckstrin homology domain containing, family J member 1 4.628
COG4 component of oligomeric golgi complex 4 4.5836
GARRE1 granule associated Rac and RHOG effector 1 4.5363
RET ret proto-oncogene 4.34787
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 4.1422
TFG TRK-fused gene 4.0699
MBNL1 muscleblind-like splicing regulator 1 4.06637
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.0574
PLPP2 phospholipid phosphatase 2 3.9323
COX6C cytochrome c oxidase subunit VIc 3.9237
CLTC clathrin, heavy chain (Hc) 3.851
SCGB2A1 secretoglobin, family 2A, member 1 3.8001
SCYL3 SCY1-like 3 (S. cerevisiae) 3.79235
TNIP1 TNFAIP3 interacting protein 1 3.7903
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.7182
TDP1 tyrosyl-DNA phosphodiesterase 1 3.6854
HLA-DMB major histocompatibility complex, class II, DM beta 3.6724
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 3.65835
PGAM4 phosphoglycerate mutase family member 4 3.6133
SDCBP syndecan binding protein (syntenin) 3.6107
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.6094
RBM15B RNA binding motif protein 15B 3.596
PLAGL1 pleiomorphic adenoma gene-like 1 3.5662
MAGED1 melanoma antigen family D1 3.5338
AHNAK2 AHNAK nucleoprotein 2 3.4717
RTN4 reticulon 4 3.43363
MAEA macrophage erythroblast attacher 3.391
ITPRID2 ITPR interacting domain containing 2 3.3518
MFAP4 microfibrillar-associated protein 4 3.3044
OXCT1 3-oxoacid CoA transferase 1 3.2858
SRSF8 serine/arginine-rich splicing factor 8 3.24735
MICB MHC class I polypeptide-related sequence B 3.1908
PLSCR3 phospholipid scramblase 3 3.18325
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 3.1696
NRTN neurturin 3.1687
NUDC nudC nuclear distribution protein 3.16515
ROPN1B rhophilin associated tail protein 1B 3.1561
ACBD3 acyl-CoA binding domain containing 3 3.1552
CREG1 cellular repressor of E1A-stimulated genes 1 3.1525
MRPL18 mitochondrial ribosomal protein L18 3.1429
MAGEA6 melanoma antigen family A6 3.1397
RHOA ras homolog family member A 3.13535
SCPEP1 serine carboxypeptidase 1 3.1352
PAQR3 progestin and adipoQ receptor family member III 3.1103
TSPYL4 TSPY-like 4 3.097
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 3.07853
SETD1B SET domain containing 1B 3.069
ARHGAP4 Rho GTPase activating protein 4 3.0678
STXBP3 syntaxin binding protein 3 3.0594
KLF10 Kruppel-like factor 10 3.0592
HMGN3 high mobility group nucleosomal binding domain 3 3.0563
HOXB5 homeobox B5 3.05495
BBOF1 basal body orientation factor 1 3.0488
CTSL cathepsin L 3.0136
STMN2 stathmin 2 3.0136
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 3.0104
SYNGR2 synaptogyrin 2 3.008
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 3.0052
HDAC2 histone deacetylase 2 3.0013
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.9873
PEPD peptidase D 2.9752
MMP11 matrix metallopeptidase 11 2.9653
FZD6 frizzled class receptor 6 2.9628
INTS12 integrator complex subunit 12 2.9577
VPREB1 pre-B lymphocyte 1 2.9511
MRPL42 mitochondrial ribosomal protein L42 2.9503
SNRPC small nuclear ribonucleoprotein polypeptide C 2.9441
NSG2 neuronal vesicle trafficking associated 2 2.9385
TUBA4B tubulin, alpha 4b 2.929
TP53I3 tumor protein p53 inducible protein 3 2.9252
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.9186
UBAC1 UBA domain containing 1 2.9168
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.914
JMJD1C jumonji domain containing 1C 2.9066
SEC13 SEC13 homolog (S. cerevisiae) 2.9017
RB1CC1 RB1-inducible coiled-coil 1 2.8999
ENOPH1 enolase-phosphatase 1 2.8977
MLF1 myeloid leukemia factor 1 2.89185
DAZAP2 DAZ associated protein 2 2.8814
PTX3 pentraxin 3, long 2.8802
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.8549
COIL coilin 2.84125
WASF3 WAS protein family, member 3 2.8276
FAM3C family with sequence similarity 3, member C 2.8269
OAZ1 ornithine decarboxylase antizyme 1 2.82595
TCIM transcriptional and immune response regulator 2.8217
DIABLO diablo, IAP-binding mitochondrial protein 2.821
NPY neuropeptide Y 2.8209
DSG2 desmoglein 2 2.8202
HMGB3 high mobility group box 3 2.8198
PARP1 poly (ADP-ribose) polymerase 1 2.8187
MAGEA1 melanoma antigen family A1 2.816
AGO2 argonaute RISC catalytic component 2 2.8156
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.8048
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.8037
MTCH2 mitochondrial carrier 2 2.7998
SCGB2A2 secretoglobin, family 2A, member 2 2.7918
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.7898
HSPA1A heat shock 70kDa protein 1A 2.7877
CCNJ cyclin J 2.7874
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.7775
DNTT DNA nucleotidylexotransferase 2.7455
SCGB1D2 secretoglobin, family 1D, member 2 2.743
SLC35G2 solute carrier family 35, member G2 2.7413
ENY2 enhancer of yellow 2 homolog (Drosophila) 2.737
CNGA3 cyclic nucleotide gated channel alpha 3 2.7343
TFCP2L1 transcription factor CP2-like 1 2.7317
NINJ2 ninjurin 2 2.7273
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.7197
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.71735
CCDC91 coiled-coil domain containing 91 2.7117
RSRC2 arginine/serine-rich coiled-coil 2 2.7013
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 2.70103
RUVBL2 RuvB-like AAA ATPase 2 2.6995
TRIM37 tripartite motif containing 37 2.6963
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.6957
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.69545
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.6945
TPD52L2 tumor protein D52-like 2 2.6877
DEDD death effector domain containing 2.6797
CDC34 cell division cycle 34 2.6757
PABPC3 poly(A) binding protein, cytoplasmic 3 2.6745
PELI1 pellino E3 ubiquitin protein ligase 1 2.669
ZMYND10 zinc finger, MYND-type containing 10 2.66675
BAHCC1 BAH domain and coiled-coil containing 1 2.6662
USF2 upstream transcription factor 2, c-fos interacting 2.65907
MAPK6 mitogen-activated protein kinase 6 2.6583
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.6499
LAPTM4B lysosomal protein transmembrane 4 beta 2.64757
SRY sex determining region Y 2.6424
CCNO cyclin O 2.64
DNAAF11 dynein axonemal assembly factor 11 2.6369
LGSN lengsin, lens protein with glutamine synthetase domain 2.628
TM2D1 TM2 domain containing 1 2.62585
RPL34 ribosomal protein L34 2.619
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.6175
ACOT2 acyl-CoA thioesterase 2 2.6145
RIOK2 RIO kinase 2 2.6094
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.5999
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.5838
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.5809
LDHB lactate dehydrogenase B 2.5795
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.57915
NNMT nicotinamide N-methyltransferase 2.57785
EFHD1 EF-hand domain family, member D1 2.5765
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.5732
ZFTA zinc finger translocation associated 2.5689
HBZ hemoglobin, zeta 2.5671
JPT2 Jupiter microtubule associated homolog 2 2.56017
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.5553
PANK3 pantothenate kinase 3 2.5525
SH3YL1 SH3 and SYLF domain containing 1 2.5525
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.5522
DCP2 decapping mRNA 2 2.5461
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.546
WDTC1 WD and tetratricopeptide repeats 1 2.54147
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.5381
STIM1 stromal interaction molecule 1 2.5318
HSPA4L heat shock 70kDa protein 4-like 2.5277
STARD3 StAR-related lipid transfer (START) domain containing 3 2.5247
PLK1 polo-like kinase 1 2.5205
SPAG1 sperm associated antigen 1 2.5203
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.51865
KEL Kell blood group, metallo-endopeptidase 2.5136
LAMP5 lysosomal-associated membrane protein family, member 5 2.5036
CYB5R3 cytochrome b5 reductase 3 2.4947
RPS27 ribosomal protein S27 2.4913
LYPLA1 lysophospholipase I 2.4842
STX1A syntaxin 1A (brain) 2.4797
KIFAP3 kinesin-associated protein 3 2.4779
TM2D3 TM2 domain containing 3 2.4757
RGS4 regulator of G-protein signaling 4 2.4745
GPX4 glutathione peroxidase 4 2.4727
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.47185
EMC2 ER membrane protein complex subunit 2 2.4718
SSNA1 Sjogren syndrome nuclear autoantigen 1 2.4633
NCSTN nicastrin 2.4481
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 2.4481
KRT5 keratin 5, type II 2.4472
ZBBX zinc finger, B-box domain containing 2.4422
CD8A CD8a molecule 2.4321
PNISR PNN-interacting serine/arginine-rich protein 2.43043
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.42545
TFRC transferrin receptor 2.42095
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.4192
GOLGA8N golgin A8 family, member N 2.4163
RIDA reactive intermediate imine deaminase A homolog 2.4158
NSD2 nuclear receptor binding SET domain protein 2 2.4149
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 2.4109
ANKRD37 ankyrin repeat domain 37 2.4082
RHD Rh blood group, D antigen 2.4032
NDRG4 NDRG family member 4 2.4026
VRK3 vaccinia related kinase 3 2.4008
HMGA2 high mobility group AT-hook 2 2.3958
CUEDC1 CUE domain containing 1 2.3952
NUP107 nucleoporin 107kDa 2.3932
IP6K2 inositol hexakisphosphate kinase 2 2.3923
BSPRY B-box and SPRY domain containing 2.3921
RMDN1 regulator of microtubule dynamics 1 2.3887
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.3829
SOX4 SRY (sex determining region Y)-box 4 2.37555
RAB4B RAB4B, member RAS oncogene family 2.3754
PPME1 protein phosphatase methylesterase 1 2.3606
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.359
SNRPN small nuclear ribonucleoprotein polypeptide N 2.35765
TMEM231 transmembrane protein 231 2.35185
ACR acrosin 2.3494
CARTPT CART prepropeptide 2.349
LDHA lactate dehydrogenase A 2.3479
TSLIG3A tRNA splicing ligase complex subunit 3A 2.3446
MED23 mediator complex subunit 23 2.3439
RPH3A rabphilin 3A 2.3325
LAP3 leucine aminopeptidase 3 2.3304
PPOX protoporphyrinogen oxidase 2.3298
FZD2 frizzled class receptor 2 2.3282
YPEL1 yippee-like 1 (Drosophila) 2.3251
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.3221
HOXB7 homeobox B7 2.32183
ARF1 ADP-ribosylation factor 1 2.319
RLIM ring finger protein, LIM domain interacting 2.3172
ZFAND5 zinc finger, AN1-type domain 5 2.3136
IL12A interleukin 12A 2.3084
DNAI1 dynein, axonemal, intermediate chain 1 2.308
SEC16A SEC16 homolog A (S. cerevisiae) 2.304
MYO5C myosin VC 2.3015
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.29375
SLC75A1 solute carrier family 75 member 1 2.29
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.2896
CAPRIN2 caprin family member 2 2.2882
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.2881
MRPL15 mitochondrial ribosomal protein L15 2.2877
TXNRD1 thioredoxin reductase 1 2.2836
PCCB propionyl CoA carboxylase, beta polypeptide 2.2794
TPPP3 tubulin polymerization-promoting protein family member 3 2.2746
NPC2 Niemann-Pick disease, type C2 2.2741
QDPR quinoid dihydropteridine reductase 2.2726
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 2.2717
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.2707
HNRNPM heterogeneous nuclear ribonucleoprotein M 2.2701
SCD stearoyl-CoA desaturase (delta-9-desaturase) 2.26788
FXYD3 FXYD domain containing ion transport regulator 3 2.26675
ECHDC1 ethylmalonyl-CoA decarboxylase 1 2.2654
LMO2 LIM domain only 2 (rhombotin-like 1) 2.2628
C4BPA complement component 4 binding protein, alpha 2.2561
RECQL4 RecQ protein-like 4 2.2552
CAVIN3 caveolae associated protein 3 2.2528
DTNB dystrobrevin, beta 2.2515
MFAP2 microfibrillar-associated protein 2 2.2507
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 2.2491
HLTF helicase-like transcription factor 2.2444
GALC galactosylceramidase 2.24405
A1CF APOBEC1 complementation factor 2.244
TPST1 tyrosylprotein sulfotransferase 1 2.2439
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.23961
PLGLB2 plasminogen-like B2 2.23775
RPLP0 ribosomal protein, large, P0 2.23362
SCAND1 SCAN domain containing 1 2.2316
CEP350 centrosomal protein 350kDa 2.22865
SPEF1 sperm flagellar 1 2.2285
SCT secretin 2.2246
CEP43 centrosomal protein 43 2.2214
ARL2 ADP-ribosylation factor-like 2 2.2208
RIBC2 RIB43A domain with coiled-coils 2 2.2208
GNA12 guanine nucleotide binding protein (G protein) alpha 12 2.2185
PHF10 PHD finger protein 10 2.2178
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.2177
CHGB chromogranin B 2.2166
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.2153
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.2132
RPL6 ribosomal protein L6 2.2104
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.2092
ARF4 ADP-ribosylation factor 4 2.2086
LZTFL1 leucine zipper transcription factor-like 1 2.2084
TBC1D13 TBC1 domain family, member 13 2.2065
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.20635
BSG basigin (Ok blood group) 2.2039
MORF4L2 mortality factor 4 like 2 2.2036
HMOX1 heme oxygenase 1 2.2025
PARD6A par-6 family cell polarity regulator alpha 2.202
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.2019
RTL8C retrotransposon Gag like 8C 2.196
SCAF8 SR-related CTD-associated factor 8 2.1943
LOC102724428 serine/threonine-protein kinase SIK1 2.1937
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.1917
ZBTB38 zinc finger and BTB domain containing 38 2.1905
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.1888
ZFPM1 zinc finger protein, FOG family member 1 2.1887
ART3 ADP-ribosyltransferase 3 2.1881
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 2.1881
EIF6 eukaryotic translation initiation factor 6 2.1874
COL16A1 collagen, type XVI, alpha 1 2.1854
PTPRT protein tyrosine phosphatase, receptor type, T 2.1851
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.18335
UBE2D3 ubiquitin-conjugating enzyme E2D 3 2.178
IGF2R insulin-like growth factor 2 receptor 2.1747
XPO6 exportin 6 2.1701
RPS23 ribosomal protein S23 2.1681
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 2.16755
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.1661
CALY calcyon neuron-specific vesicular protein 2.1633
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.1613
CEP83 centrosomal protein 83kDa 2.1596
CAAP1 caspase activity and apoptosis inhibitor 1 2.1587
SNX16 sorting nexin 16 2.1571
PTK2 protein tyrosine kinase 2 2.1505
ANAPC5 anaphase promoting complex subunit 5 2.14845
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.1477
SCG2 secretogranin II 2.1448
ARID4B AT rich interactive domain 4B (RBP1-like) 2.1445
MACIR macrophage immunometabolism regulator 2.1411
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.13977
SRPX sushi-repeat containing protein, X-linked 2.136
LMO1 LIM domain only 1 (rhombotin 1) 2.1345
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.1306
RAB5IF RAB5 interacting factor 2.1295
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.1288
DNAAF2 dynein, axonemal, assembly factor 2 2.1282
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 2.12807
PODXL podocalyxin-like 2.1251
TPH1 tryptophan hydroxylase 1 2.123
LOC128966570 alpha-amylase 1B 2.1175
ZBTB35 zinc finger and BTB domain containing 35 2.117
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.1124
FBLN5 fibulin 5 2.1112
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.11115
PFKM phosphofructokinase, muscle 2.11
GSTP1 glutathione S-transferase pi 1 2.1049
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 2.1027
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.1016
TH tyrosine hydroxylase 2.101
TCERG1 transcription elongation regulator 1 2.1004
RPS13 ribosomal protein S13 2.1
MRPL30 mitochondrial ribosomal protein L30 2.0998
CDCA4 cell division cycle associated 4 2.0997
JAM2 junctional adhesion molecule 2 2.0969
MLXIP MLX interacting protein 2.09675
AAAS achalasia, adrenocortical insufficiency, alacrimia 2.0965
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.0964
FAM117A family with sequence similarity 117, member A 2.096
IRF8 interferon regulatory factor 8 2.0957
ORC3 origin recognition complex, subunit 3 2.0907
PM20D1 peptidase M20 domain containing 1 2.0901
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.0899
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.08888
FBXW2 F-box and WD repeat domain containing 2 2.08805
CCDC68 coiled-coil domain containing 68 2.0815
MELK maternal embryonic leucine zipper kinase 2.0802
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.07365
ZNF518A zinc finger protein 518A 2.0722
BID BH3 interacting domain death agonist 2.0689
TTYH1 tweety family member 1 2.0677
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2.0672
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.0657
BMPR1B bone morphogenetic protein receptor, type IB 2.0652
TBC1D12 TBC1 domain family, member 12 2.0648
CCL23 chemokine (C-C motif) ligand 23 2.0595
CRELD1 cysteine-rich with EGF-like domains 1 2.0586
EIF4H eukaryotic translation initiation factor 4H 2.0578
SAP25 Sin3A-associated protein, 25kDa 2.05585
NOAZFP nucleolar atypical zinc finger 2.0553
RRAGA Ras-related GTP binding A 2.0553
CLASRP CLK4-associating serine/arginine rich protein 2.0545
RPS15 ribosomal protein S15 2.0545
MPHOSPH6 M-phase phosphoprotein 6 2.0486
F9 coagulation factor IX 2.0433
DNM1L dynamin 1-like 2.0424
PGR progesterone receptor 2.0422
NTF3 neurotrophin 3 2.0405
SPAG6 sperm associated antigen 6 2.0404
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.0402
FKTN fukutin 2.0375
VCPKMT valosin containing protein lysine (K) methyltransferase 2.0346
INA internexin neuronal intermediate filament protein, alpha 2.0343
TRAPPC12 trafficking protein particle complex 12 2.0326
ZBTB39 zinc finger and BTB domain containing 39 2.0314
TGFBI transforming growth factor, beta-induced, 68kDa 2.0279
BDNF brain-derived neurotrophic factor 2.0274
RPL39 ribosomal protein L39 2.0245
EFHC1 EF-hand domain (C-terminal) containing 1 2.0236
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.01745
PLAGL2 pleiomorphic adenoma gene-like 2 2.01575
CBARP CACN subunit beta associated regulatory protein 2.0144
ADGB androglobin 2.0086
CST2 cystatin SA 2.0085
EFCAB11 EF-hand calcium binding domain 11 2.0074
RPL7A ribosomal protein L7a 2.0034
HTN1 histatin 1 2.002
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.00117
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.001

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -10.0
CCNB1 cyclin B1 -10.0
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -10.0
SLC35F2 solute carrier family 35, member F2 -9.4587
PCNA proliferating cell nuclear antigen -8.6807
MCM3 minichromosome maintenance complex component 3 -7.8773
CRK v-crk avian sarcoma virus CT10 oncogene homolog -7.1427
TM9SF3 transmembrane 9 superfamily member 3 -7.0601
NT5DC2 5'-nucleotidase domain containing 2 -6.7096
YME1L1 YME1-like 1 ATPase -6.44183
GRWD1 glutamate-rich WD repeat containing 1 -6.4338
GTPBP8 GTP-binding protein 8 (putative) -5.8841
RPIA ribose 5-phosphate isomerase A -5.6611
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -5.471
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -5.2702
LOC124907782 dual specificity protein phosphatase 22 -5.194
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -5.1762
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -4.7751
TBX2 T-box 2 -4.69457
GSTM2 glutathione S-transferase mu 2 (muscle) -4.58
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -4.4243
ZNF430 zinc finger protein 430 -4.3876
MCMBP minichromosome maintenance complex binding protein -4.3309
SYNE2 spectrin repeat containing, nuclear envelope 2 -4.3074
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -4.2653
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.2311
PRKCD protein kinase C, delta -4.1787
DENND4C DENN/MADD domain containing 4C -4.1506
BLMH bleomycin hydrolase -4.0804
TSKU tsukushi, small leucine rich proteoglycan -4.0728
KIF14 kinesin family member 14 -4.0518
WDR7 WD repeat domain 7 -4.0166
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.9702
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -3.9092
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -3.7823
CDKN2A cyclin-dependent kinase inhibitor 2A -3.76343
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -3.7241
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -3.71625
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -3.7095
FBXO46 F-box protein 46 -3.7021
EIF3I eukaryotic translation initiation factor 3, subunit I -3.6723
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -3.6646
FBXO40 F-box protein 40 -3.6603
ZNF586 zinc finger protein 586 -3.6433
SCIN scinderin -3.642
MAGT1 magnesium transporter 1 -3.6397
RBM10 RNA binding motif protein 10 -3.639
SLN sarcolipin -3.6244
LYRM4 LYR motif containing 4 -3.5826
ACADVL acyl-CoA dehydrogenase, very long chain -3.5822
KIAA0319 KIAA0319 -3.53
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -3.5286
IL22RA1 interleukin 22 receptor, alpha 1 -3.5161
DCLRE1B DNA cross-link repair 1B -3.4896
MTPAP mitochondrial poly(A) polymerase -3.4832
DBF4B DBF4 zinc finger B -3.4507
HYOU1 hypoxia up-regulated 1 -3.4342
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -3.433
CHMP4B charged multivesicular body protein 4B -3.42395
EPN3 epsin 3 -3.4175
LOC128966622 putative protein N-methyltransferase FAM86B2 -3.4171
ZNF322 zinc finger protein 322 -3.4156
AURKA aurora kinase A -3.4061
SREK1IP1 SREK1-interacting protein 1 -3.3372
TRIM13 tripartite motif containing 13 -3.3286
CYBB cytochrome b-245, beta polypeptide -3.31895
FAM204A family with sequence similarity 204, member A -3.3167
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -3.3123
SF3A3 splicing factor 3a, subunit 3, 60kDa -3.3085
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -3.3045
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -3.29955
MAP2K5 mitogen-activated protein kinase kinase 5 -3.28707
HBEGF heparin-binding EGF-like growth factor -3.26765
CGB8 chorionic gonadotropin, beta polypeptide 8 -3.2325
ZNF248 zinc finger protein 248 -3.2287
KPNA6 karyopherin alpha 6 (importin alpha 7) -3.22577
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -3.2249
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -3.21875
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -3.21
MCM10 minichromosome maintenance complex component 10 -3.1904
PCGF2 polycomb group ring finger 2 -3.1714
ZFP36 ZFP36 ring finger protein -3.1629
TMEM35A transmembrane protein 35A -3.1539
DCSTAMP dendrocyte expressed seven transmembrane protein -3.1498
NCF2 neutrophil cytosolic factor 2 -3.1337
AMBRA1 autophagy/beclin-1 regulator 1 -3.1226
PGLS 6-phosphogluconolactonase -3.11935
GSTM4 glutathione S-transferase mu 4 -3.1123
SH2B2 SH2B adaptor protein 2 -3.1086
MYOZ1 myozenin 1 -3.1065
AK6 adenylate kinase 6 -3.0996
SMYD5 SMYD family member 5 -3.0995
NABP2 nucleic acid binding protein 2 -3.0978
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -3.0774
STARD8 StAR-related lipid transfer (START) domain containing 8 -3.0678
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -3.0638
ARMCX4 armadillo repeat containing, X-linked 4 -3.0485
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.03647
TSPOAP1 TSPO associated protein 1 -3.0281
MAP2K4 mitogen-activated protein kinase kinase 4 -3.0267
CDH12 cadherin 12, type 2 (N-cadherin 2) -3.0261
DIO2 deiodinase, iodothyronine, type II -3.02457
ZNF580 zinc finger protein 580 -3.0151
MCM6 minichromosome maintenance complex component 6 -3.0105
SPTBN4 spectrin, beta, non-erythrocytic 4 -2.9976
PPP1R10 protein phosphatase 1, regulatory subunit 10 -2.99465
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -2.9933
AUNIP aurora kinase A and ninein interacting protein -2.9867
EFNB1 ephrin-B1 -2.9816
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.9794
MMP8 matrix metallopeptidase 8 -2.9715
KCTD14 potassium channel tetramerization domain containing 14 -2.9654
JUN jun proto-oncogene -2.9621
ATP10B ATPase, class V, type 10B -2.94545
BHLHE41 basic helix-loop-helix family, member e41 -2.9397
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -2.9383
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.9353
C1QBP complement component 1, q subcomponent binding protein -2.9328
SARS1 seryl-tRNA synthetase 1 -2.9326
CHIT1 chitinase 1 (chitotriosidase) -2.9301
EPS8L1 EPS8-like 1 -2.92204
UNC13D unc-13 homolog D (C. elegans) -2.9206
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -2.9199
ZNF276 zinc finger protein 276 -2.9184
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -2.9174
OBP2A odorant binding protein 2A -2.9029
OSBPL10 oxysterol binding protein-like 10 -2.8972
GATAD1 GATA zinc finger domain containing 1 -2.89017
HEATR3 HEAT repeat containing 3 -2.8878
ZNF665 zinc finger protein 665 -2.88
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E -2.8669
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.8651
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.8636
NRF1 nuclear respiratory factor 1 -2.8551
RRAGB Ras-related GTP binding B -2.8482
OVCA2 ovarian tumor suppressor candidate 2 -2.8463
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.8407
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -2.8354
CDC42 cell division cycle 42 -2.83235
LIFR leukemia inhibitory factor receptor alpha -2.8259
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.8216
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -2.82013
MMP9 matrix metallopeptidase 9 -2.8166
ZHX2 zinc fingers and homeoboxes 2 -2.813
PDIA3 protein disulfide isomerase family A, member 3 -2.7932
ZNF282 zinc finger protein 282 -2.7927
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.7815
CCR6 chemokine (C-C motif) receptor 6 -2.7745
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.772
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.7714
INHA inhibin, alpha -2.7637
ZNF124 zinc finger protein 124 -2.7569
TFF2 trefoil factor 2 -2.7551
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.7519
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.7469
IL10RB interleukin 10 receptor, beta -2.7411
PRCP prolylcarboxypeptidase (angiotensinase C) -2.7357
GPC1 glypican 1 -2.7342
RIPK4 receptor-interacting serine-threonine kinase 4 -2.719
SPATS2 spermatogenesis associated, serine-rich 2 -2.7164
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.71603
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.7078
TBX3 T-box 3 -2.7054
BPHL biphenyl hydrolase-like (serine hydrolase) -2.6954
NDRG3 NDRG family member 3 -2.6946
HDDC2 HD domain containing 2 -2.6899
RACGAP1 Rac GTPase activating protein 1 -2.6895
TENM4 teneurin transmembrane protein 4 -2.6884
ASCC2 activating signal cointegrator 1 complex subunit 2 -2.686
SMPX small muscle protein, X-linked -2.6806
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.6732
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.6677
SRR serine racemase -2.66575
PYCARD PYD and CARD domain containing -2.6655
MARK2 MAP/microtubule affinity-regulating kinase 2 -2.6622
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.6593
ANXA10 annexin A10 -2.6531
CTNND1 catenin (cadherin-associated protein), delta 1 -2.64687
MYOT myotilin -2.643
MUC3B mucin 3B, cell surface associated -2.635
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.6289
TBXAS1 thromboxane A synthase 1 (platelet) -2.6266
UBE3C ubiquitin protein ligase E3C -2.6214
BMP6 bone morphogenetic protein 6 -2.6147
COMMD3 COMM domain containing 3 -2.6122
LDB3 LIM domain binding 3 -2.61123
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.6048
TEX11 testis expressed 11 -2.6016
MRPL4 mitochondrial ribosomal protein L4 -2.6011
DYNLT3 dynein, light chain, Tctex-type 3 -2.598
THOC7 THO complex 7 -2.5964
ERAP2 endoplasmic reticulum aminopeptidase 2 -2.595
RPN1 ribophorin I -2.5828
RLF rearranged L-myc fusion -2.5812
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -2.5806
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.5682
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.5669
NCS1 neuronal calcium sensor 1 -2.5656
DHRS9 dehydrogenase/reductase (SDR family) member 9 -2.5652
WAC WW domain containing adaptor with coiled-coil -2.56025
SPIN2A spindlin family, member 2A -2.5579
DNM2 dynamin 2 -2.5567
AK4 adenylate kinase 4 -2.5562
OBP2B odorant binding protein 2B -2.5553
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.554
KCNK10 potassium channel, two pore domain subfamily K, member 10 -2.5536
GATAD2A GATA zinc finger domain containing 2A -2.5494
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 -2.548
ZNF426 zinc finger protein 426 -2.5477
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.5411
LMNB1 lamin B1 -2.538
MSH3 mutS homolog 3 -2.53545
KYAT3 kynurenine aminotransferase 3 -2.5332
CSTA cystatin A (stefin A) -2.5259
EFR3B EFR3 homolog B (S. cerevisiae) -2.52
PHKA2 phosphorylase kinase, alpha 2 (liver) -2.5141
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.514
IL36G interleukin 36, gamma -2.5131
CLEC5A C-type lectin domain family 5, member A -2.5092
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.5068
CYTL1 cytokine-like 1 -2.5067
LRRC61 leucine rich repeat containing 61 -2.5007
CDC42SE1 CDC42 small effector 1 -2.4907
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -2.4887
PAGE4 P antigen family, member 4 (prostate associated) -2.4882
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -2.4874
ARG2 arginase 2 -2.48655
KRT76 keratin 76, type II -2.485
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) -2.4833
PFDN1 prefoldin subunit 1 -2.4828
METTL2A methyltransferase like 2A -2.48165
PDIA4 protein disulfide isomerase family A, member 4 -2.4797
TXNDC15 thioredoxin domain containing 15 -2.4771
TCEAL2 transcription elongation factor A (SII)-like 2 -2.4755
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.47505
CTSB cathepsin B -2.4729
NUBPL nucleotide binding protein-like -2.472
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -2.4704
RBMX2 RNA binding motif protein, X-linked 2 -2.46945
IL1RN interleukin 1 receptor antagonist -2.46665
QSER1 glutamine and serine rich 1 -2.4664
ZNF324 zinc finger protein 324 -2.4615
MYH2 myosin, heavy chain 2, skeletal muscle, adult -2.4608
SKIC8 SKI8 subunit of superkiller complex -2.448
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.446
DCAF10 DDB1 and CUL4 associated factor 10 -2.4423
GPRC5B G protein-coupled receptor, class C, group 5, member B -2.4389
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) -2.4388
BCL2A1 BCL2-related protein A1 -2.4388
PITPNA phosphatidylinositol transfer protein, alpha -2.4383
SMG6 SMG6 nonsense mediated mRNA decay factor -2.434
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.4327
UBE2O ubiquitin-conjugating enzyme E2O -2.4324
XPO4 exportin 4 -2.4257
YAP1 Yes-associated protein 1 -2.4253
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.4245
KIF4A kinesin family member 4A -2.4228
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -2.4221
PPP1R12B protein phosphatase 1, regulatory subunit 12B -2.42175
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.4201
TRIM16 tripartite motif containing 16 -2.4196
NMRK1 nicotinamide riboside kinase 1 -2.4183
UEVLD UEV and lactate/malate dehyrogenase domains -2.4176
FHIT fragile histidine triad -2.4171
RSL1D1 ribosomal L1 domain containing 1 -2.41493
INTS5 integrator complex subunit 5 -2.4146
FXR2 fragile X mental retardation, autosomal homolog 2 -2.4087
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.4045
AFF4 AF4/FMR2 family, member 4 -2.3994
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -2.387
TOMM34 translocase of outer mitochondrial membrane 34 -2.3822
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -2.3804
SCD5 stearoyl-CoA desaturase 5 -2.3781
FHL5 four and a half LIM domains 5 -2.3768
CADPS2 Ca++-dependent secretion activator 2 -2.3732
WT1 Wilms tumor 1 -2.37225
MEFV Mediterranean fever -2.3722
IPO5 importin 5 -2.37145
ERCC4 excision repair cross-complementation group 4 -2.3706
CNGB3 cyclic nucleotide gated channel beta 3 -2.3702
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.3674
GPRC5C G protein-coupled receptor, class C, group 5, member C -2.3638
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.3625
HDLBP high density lipoprotein binding protein -2.36135
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 -2.3608
WDR76 WD repeat domain 76 -2.3608
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.3585
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.3558
DERL2 derlin 2 -2.3534
CD163L1 CD163 molecule-like 1 -2.3531
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -2.35277
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.3519
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.3515
ZNF506 zinc finger protein 506 -2.3514
SZT2 seizure threshold 2 homolog (mouse) -2.351
MEA1 male-enhanced antigen 1 -2.3503
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like -2.3491
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.3482
TBL1X transducin (beta)-like 1X-linked -2.34643
PTCH2 patched 2 -2.3463
GCLC glutamate-cysteine ligase, catalytic subunit -2.3442
CCND2 cyclin D2 -2.3396
APEH acylaminoacyl-peptide hydrolase -2.3394
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.3375
DMAC2L distal membrane arm assembly component 2 like -2.3359
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -2.3351
CTCF CCCTC-binding factor (zinc finger protein) -2.3342
CAMTA2 calmodulin binding transcription activator 2 -2.3309
SUN2 Sad1 and UNC84 domain containing 2 -2.33
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.3292
KRT4 keratin 4, type II -2.3255
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.3253
TYRO3 TYRO3 protein tyrosine kinase -2.32525
BCKDK branched chain ketoacid dehydrogenase kinase -2.3232
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -2.32295
VPS9D1 VPS9 domain containing 1 -2.3225
PTOV1 prostate tumor overexpressed 1 -2.321
CCDC22 coiled-coil domain containing 22 -2.3182
THNSL2 threonine synthase-like 2 (S. cerevisiae) -2.3179
TNF tumor necrosis factor -2.316
TNPO1 transportin 1 -2.31538
CMTR1 cap methyltransferase 1 -2.3132
LPAR6 lysophosphatidic acid receptor 6 -2.311
FAN1 FANCD2/FANCI-associated nuclease 1 -2.3103
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -2.3095
PHACTR4 phosphatase and actin regulator 4 -2.3064
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.3061
SSBP3 single stranded DNA binding protein 3 -2.3046
SERGEF secretion regulating guanine nucleotide exchange factor -2.2986
TP53BP1 tumor protein p53 binding protein 1 -2.29665
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.2964
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.2958
EXD2 exonuclease 3'-5' domain containing 2 -2.2916
MYO15A myosin XVA -2.291
WDR5B WD repeat domain 5B -2.2879
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.2878
LRRTM2 leucine rich repeat transmembrane neuronal 2 -2.2869
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -2.2857
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -2.2814
KRT32 keratin 32, type I -2.2803
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.2781
FANCF Fanconi anemia, complementation group F -2.2772
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.27607
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.27535
UFSP2 UFM1-specific peptidase 2 -2.2704
DOCK3 dedicator of cytokinesis 3 -2.2676
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -2.26712
AOC2 amine oxidase, copper containing 2 (retina-specific) -2.267
RRM2 ribonucleotide reductase M2 -2.26505
ARMH3 armadillo like helical domain containing 3 -2.26375
PDGFA platelet-derived growth factor alpha polypeptide -2.26235
GTPBP2 GTP binding protein 2 -2.2622
FBXL18 F-box and leucine-rich repeat protein 18 -2.26155
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -2.2613
ABI1 abl-interactor 1 -2.2601
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.2568
CCL7 chemokine (C-C motif) ligand 7 -2.2527
NANOS1 nanos homolog 1 (Drosophila) -2.2502
TPMT thiopurine S-methyltransferase -2.24975
MIS12 MIS12 kinetochore complex component -2.2487
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -2.24822
MEAF6 MYST/Esa1-associated factor 6 -2.2476
CLEC4E C-type lectin domain family 4, member E -2.2442
SMAD5 SMAD family member 5 -2.24295
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.2412
TMEM100 transmembrane protein 100 -2.2409
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.2393
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -2.2371
CDK3 cyclin-dependent kinase 3 -2.2333
ZFYVE26 zinc finger, FYVE domain containing 26 -2.23305
LOC102724560 cystathionine beta-synthase -2.2321
SARM1 sterile alpha and TIR motif containing 1 -2.23185
MYOZ3 myozenin 3 -2.2315
TMEM35B transmembrane protein 35B -2.23005
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -2.2293
TMEM80 transmembrane protein 80 -2.22625
CDK14 cyclin-dependent kinase 14 -2.223
NLGN4X neuroligin 4, X-linked -2.2191
HOMER1 homer scaffolding protein 1 -2.2188
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.21745
IPP intracisternal A particle-promoted polypeptide -2.2157
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -2.2155
PCDHGB5 protocadherin gamma subfamily B, 5 -2.2117
STON1 stonin 1 -2.2081
NSG1 neuron specific gene family member 1 -2.2048
HIPK2 homeodomain interacting protein kinase 2 -2.2029
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 -2.2024
PEX11A peroxisomal biogenesis factor 11 alpha -2.2019
AMOTL2 angiomotin like 2 -2.2009
IMPG2 interphotoreceptor matrix proteoglycan 2 -2.2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -2.1981
MYT1 myelin transcription factor 1 -2.1971
GIN1 gypsy retrotransposon integrase 1 -2.1956
UPP1 uridine phosphorylase 1 -2.1955
AQP9 aquaporin 9 -2.1911
SNX6 sorting nexin 6 -2.1901
TUBGCP4 tubulin, gamma complex associated protein 4 -2.1894
ZBTB22 zinc finger and BTB domain containing 22 -2.1893
TBC1D10B TBC1 domain family, member 10B -2.1892
SCARA3 scavenger receptor class A, member 3 -2.1884
SHOX short stature homeobox -2.1876
ZMYM4 zinc finger, MYM-type 4 -2.18577
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.1775
ADGRF1 adhesion G protein-coupled receptor F1 -2.1773
NPIPB6 nuclear pore complex interacting protein family, member B6 -2.1768
ZNF274 zinc finger protein 274 -2.1756
NLGN4Y neuroligin 4, Y-linked -2.1736
RBBP5 retinoblastoma binding protein 5 -2.173
MOCS1 molybdenum cofactor synthesis 1 -2.1727
NPEPPS aminopeptidase puromycin sensitive -2.17178
SYN3 synapsin III -2.1713
RAB36 RAB36, member RAS oncogene family -2.1704
GOLGA8A golgin A8 family, member A -2.1697
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.1691
PEX6 peroxisomal biogenesis factor 6 -2.16895
GPHN gephyrin -2.1679
MPHOSPH8 M-phase phosphoprotein 8 -2.1673
RAP1A RAP1A, member of RAS oncogene family -2.1641
BPI bactericidal/permeability-increasing protein -2.164
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -2.1634
SRF serum response factor (c-fos serum response element-binding transcription factor) -2.16225
SDC4 syndecan 4 -2.1589
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -2.1579
ARF6 ADP-ribosylation factor 6 -2.15705
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.1565
PSEN1 presenilin 1 -2.154
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -2.1535
WASHC5 WASH complex subunit 5 -2.1534
STK16 serine/threonine kinase 16 -2.149
FAM114A2 family with sequence similarity 114, member A2 -2.1471
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -2.14692
EPS8L3 EPS8-like 3 -2.1451
FERMT1 fermitin family member 1 -2.14425
CCDC106 coiled-coil domain containing 106 -2.1433
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.1411
PTAFR platelet-activating factor receptor -2.1393
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -2.1391
TOB2 transducer of ERBB2, 2 -2.13875
SOX15 SRY (sex determining region Y)-box 15 -2.1368
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.134
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -2.13155
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.1308
LYPD1 LY6/PLAUR domain containing 1 -2.1259
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -2.1259
PROSER1 proline and serine rich 1 -2.122
MICALL2 MICAL-like 2 -2.1211
CDKN2AIP CDKN2A interacting protein -2.12
LIF leukemia inhibitory factor -2.1193
TNMD tenomodulin -2.1185
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.1181
RAB20 RAB20, member RAS oncogene family -2.1174
CYTH3 cytohesin 3 -2.1158
CENPI centromere protein I -2.11425
ZNF93 zinc finger protein 93 -2.11405
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.1134
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.1133
RSF1 remodeling and spacing factor 1 -2.113
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.1117
GPR31 G protein-coupled receptor 31 -2.1104
MARCHF1 membrane associated ring-CH-type finger 1 -2.1103
TARS1 threonyl-tRNA synthetase 1 -2.1099
CASP2 caspase 2, apoptosis-related cysteine peptidase -2.10236
TUBD1 tubulin, delta 1 -2.09865
CIAO3 cytosolic iron-sulfur assembly component 3 -2.0983
FBL fibrillarin -2.0955
IFNAR1 interferon (alpha, beta and omega) receptor 1 -2.0954
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -2.095
LAX1 lymphocyte transmembrane adaptor 1 -2.0947
NIT1 nitrilase 1 -2.0936
CPED1 cadherin-like and PC-esterase domain containing 1 -2.0936
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -2.093
LONRF3 LON peptidase N-terminal domain and ring finger 3 -2.0924
AIG1 androgen-induced 1 -2.0916
C1QTNF1 C1q and tumor necrosis factor related protein 1 -2.0887
METTL1 methyltransferase like 1 -2.0885
LYSET lysosomal enzyme trafficking factor -2.0884
ACP6 acid phosphatase 6, lysophosphatidic -2.0883
IL18 interleukin 18 -2.0881
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.0879
R3HCC1L R3H domain and coiled-coil containing 1-like -2.0877
DENND1B DENN/MADD domain containing 1B -2.0866
TMEM94 transmembrane protein 94 -2.0862
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.08615
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -2.0861
MIER2 mesoderm induction early response 1, family member 2 -2.08485
LARS1 leucyl-tRNA synthetase 1 -2.0836
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -2.0819
TMEM87A transmembrane protein 87A -2.0775
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.0774
PLN phospholamban -2.07583
KCTD13 potassium channel tetramerization domain containing 13 -2.0754
SPATA20 spermatogenesis associated 20 -2.074
ASXL3 additional sex combs like transcriptional regulator 3 -2.074
MRPL23 mitochondrial ribosomal protein L23 -2.0738
IPO13 importin 13 -2.0737
STX8 syntaxin 8 -2.0709
RBM8A RNA binding motif protein 8A -2.06955
ADGRD2 adhesion G protein-coupled receptor D2 -2.0687
GMIP GEM interacting protein -2.0664
CCL16 chemokine (C-C motif) ligand 16 -2.0644
NRSN2 neurensin 2 -2.0629
FLCN folliculin -2.0628
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -2.0608
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.0608
NELL2 NEL-like 2 (chicken) -2.0593
VSIG10 V-set and immunoglobulin domain containing 10 -2.0578
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.056
LHFPL6 LHFPL tetraspan subfamily member 6 -2.0543
MYBBP1A MYB binding protein (P160) 1a -2.0542
ZIC4 Zic family member 4 -2.0536
GSR glutathione reductase -2.0529
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.0516
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.0498
LRRC1 leucine rich repeat containing 1 -2.04955
PGM5 phosphoglucomutase 5 -2.0481
BEAN1 brain expressed, associated with NEDD4, 1 -2.046
C2CD2 C2 calcium-dependent domain containing 2 -2.0459
PQBP1 polyglutamine binding protein 1 -2.04577
GDF9 growth differentiation factor 9 -2.0455
PDE5A phosphodiesterase 5A, cGMP-specific -2.0444
METTL25B methyltransferase like 25B -2.0436
GRHL2 grainyhead-like 2 (Drosophila) -2.0435
LY6E lymphocyte antigen 6 complex, locus E -2.0423
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -2.0405
PANK4 pantothenate kinase 4 -2.0386
ZNF611 zinc finger protein 611 -2.0385
PDGFC platelet derived growth factor C -2.0369
SIN3B SIN3 transcription regulator family member B -2.0368
DEFA4 defensin, alpha 4, corticostatin -2.0357
MATN1 matrilin 1, cartilage matrix protein -2.0354
LMO4 LIM domain only 4 -2.0334
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.0322
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.0314
STK32B serine/threonine kinase 32B -2.0302
PTK2B protein tyrosine kinase 2 beta -2.0293
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.0288
DSTYK dual serine/threonine and tyrosine protein kinase -2.02853
LARP6 La ribonucleoprotein domain family, member 6 -2.0283
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -2.0275
CHAMP1 chromosome alignment maintaining phosphoprotein 1 -2.0249
PCNX2 pecanex 2 -2.02343
TMPRSS3 transmembrane protease, serine 3 -2.0224
MANF mesencephalic astrocyte-derived neurotrophic factor -2.0223
BYSL bystin-like -2.0215
MGP matrix Gla protein -2.0176
GSTT1 glutathione S-transferase theta 1 -2.0174
WDR13 WD repeat domain 13 -2.0156
MCC mutated in colorectal cancers -2.015
CCDC102B coiled-coil domain containing 102B -2.0146
CTAGE8 CTAGE family, member 8 -2.0142
RBM47 RNA binding motif protein 47 -2.0139
MAK16 MAK16 homolog (S. cerevisiae) -2.0091
CMC4 C-x(9)-C motif containing 4 -2.0063
PKM pyruvate kinase, muscle -2.00313
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -2.0011
ZNF253 zinc finger protein 253 -2.0008
DPP4 dipeptidyl-peptidase 4 -2.00017