CRCGN011_HEPG2_24H:F04 Gene Set
Genes
54 genes differentially expressed following the CRCGN011_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.20665
|
|
NOTCH1
|
notch 1
|
5.09685
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
4.50775
|
|
MAP7
|
microtubule-associated protein 7
|
3.83265
|
|
STK10
|
serine/threonine kinase 10
|
3.7241
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.4772
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.2239
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.0177
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.9846
|
|
KLHL9
|
kelch-like family member 9
|
2.93085
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.9157
|
|
CDC45
|
cell division cycle 45
|
2.82075
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.6762
|
|
RRAGA
|
Ras-related GTP binding A
|
2.67375
|
|
CHEK2
|
checkpoint kinase 2
|
2.67138
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.6585
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.60185
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.53342
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
2.44805
|
|
ASPA
|
aspartoacylase
|
2.29525
|
|
CHN1
|
chimerin 1
|
2.28635
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.26205
|
|
TLR4
|
toll-like receptor 4
|
2.19985
|
|
SMARCD3
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
|
2.199
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.1956
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.19375
|
|
TLR3
|
toll-like receptor 3
|
2.16865
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.15175
|
|
PLAT
|
plasminogen activator, tissue
|
2.0863
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-10.0
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.45115
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.06735
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.90575
|
|
SCAND1
|
SCAN domain containing 1
|
-4.87195
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.8366
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.4869
|
|
CD58
|
CD58 molecule
|
-3.62538
|
|
GNAS
|
GNAS complex locus
|
-3.61581
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.41425
|
|
CCNB2
|
cyclin B2
|
-3.1577
|
|
CDC25B
|
cell division cycle 25B
|
-3.1365
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.69665
|
|
RIT2
|
Ras-like without CAAX 2
|
-2.64805
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.61047
|
|
PTMS
|
parathymosin
|
-2.3344
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.16895
|
|
ASTN1
|
astrotactin 1
|
-2.14515
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.12702
|
|
PWP1
|
PWP1 homolog (S. cerevisiae)
|
-2.1019
|
|
SASH1
|
SAM and SH3 domain containing 1
|
-2.03113
|
|
RND2
|
Rho family GTPase 2
|
-2.02638
|
|
ASIC1
|
acid sensing (proton gated) ion channel 1
|
-2.01277
|
|
C1QL1
|
complement component 1, q subcomponent-like 1
|
-2.0027
|
