CRCGN011_HEPG2_24H:F05 Gene Set
Genes
58 genes differentially expressed following the CRCGN011_HEPG2_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
10.0
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.63615
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.344
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.2978
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.17655
|
|
MYLK
|
myosin light chain kinase
|
5.1048
|
|
NOTCH1
|
notch 1
|
4.7352
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
4.7299
|
|
CSK
|
c-src tyrosine kinase
|
4.66275
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.44175
|
|
EPHA3
|
EPH receptor A3
|
3.86915
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.83228
|
|
MAP7
|
microtubule-associated protein 7
|
3.54718
|
|
LCN2
|
lipocalin 2
|
3.50805
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.418
|
|
RNF167
|
ring finger protein 167
|
3.16
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.98695
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.88725
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.47075
|
|
FASTKD5
|
FAST kinase domains 5
|
2.45595
|
|
GPATCH8
|
G patch domain containing 8
|
2.41605
|
|
CCNF
|
cyclin F
|
2.28657
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.2056
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.1824
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.0596
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.0402
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
2.0264
|
|
THUMPD2
|
THUMP domain containing 2
|
2.0069
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-10.0
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.92835
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.88235
|
|
USP6NL
|
USP6 N-terminal like
|
-4.8427
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.80355
|
|
LDHD
|
lactate dehydrogenase D
|
-4.66975
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.2584
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-4.11933
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.1031
|
|
TCTN1
|
tectonic family member 1
|
-3.8211
|
|
CCNB2
|
cyclin B2
|
-3.7138
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.57475
|
|
GNAS
|
GNAS complex locus
|
-3.3153
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.07616
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-3.07271
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.98135
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.8792
|
|
GDF15
|
growth differentiation factor 15
|
-2.52175
|
|
SNTB2
|
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
|
-2.51045
|
|
HMG20B
|
high mobility group 20B
|
-2.44495
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.4363
|
|
LY6E
|
lymphocyte antigen 6 complex, locus E
|
-2.3946
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.3464
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.32805
|
|
CSTPP1
|
centriolar satellite-associated tubulin polyglutamylase complex regulator 1
|
-2.28245
|
|
ZNF586
|
zinc finger protein 586
|
-2.1602
|
|
IFI6
|
interferon, alpha-inducible protein 6
|
-2.1137
|
|
RNF216
|
ring finger protein 216
|
-2.10767
|
|
GFUS
|
GDP-L-fucose synthase
|
-2.04013
|
|
MXI1
|
MAX interactor 1, dimerization protein
|
-2.02905
|
