CRCGN011_HEPG2_24H:F09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

91 genes differentially expressed following the CRCGN011_HEPG2_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 9.90255
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 9.23695
CBR3 carbonyl reductase 3 5.40675
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.33705
AMDHD2 amidohydrolase domain containing 2 5.2373
PHKG2 phosphorylase kinase, gamma 2 (testis) 4.883
CSK c-src tyrosine kinase 4.66275
UBQLN2 ubiquilin 2 4.5099
E2F2 E2F transcription factor 2 4.2517
EPN2 epsin 2 4.10398
GPER1 G protein-coupled estrogen receptor 1 4.02642
NMU neuromedin U 3.82025
STK10 serine/threonine kinase 10 3.65808
SSBP2 single-stranded DNA binding protein 2 3.60037
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.5489
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.37902
GPATCH8 G patch domain containing 8 3.20267
IL24 interleukin 24 3.1139
LIME1 Lck interacting transmembrane adaptor 1 3.01715
CHN1 chimerin 1 2.9824
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.98005
DMTF1 cyclin D binding myb-like transcription factor 1 2.88093
PMM2 phosphomannomutase 2 2.87785
PRKCH protein kinase C, eta 2.87232
COL11A1 collagen, type XI, alpha 1 2.80492
ZBTB7C zinc finger and BTB domain containing 7C 2.7293
RNF167 ring finger protein 167 2.50765
INHA inhibin, alpha 2.4056
KLK13 kallikrein-related peptidase 13 2.39917
S1PR4 sphingosine-1-phosphate receptor 4 2.39085
FOXN1 forkhead box N1 2.35475
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.33065
CSN1S1 casein alpha s1 2.32665
RIGI RNA sensor RIG-I 2.322
RLBP1 retinaldehyde binding protein 1 2.2949
ZFR2 zinc finger RNA binding protein 2 2.2863
HLA-DRA major histocompatibility complex, class II, DR alpha 2.26398
KLK8 kallikrein-related peptidase 8 2.254
LSP1 lymphocyte-specific protein 1 2.24615
APEH acylaminoacyl-peptide hydrolase 2.2342
BICDL1 BICD family like cargo adaptor 1 2.1956
IQSEC1 IQ motif and Sec7 domain 1 2.18267
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.1719
GIPR gastric inhibitory polypeptide receptor 2.1683
SCRT1 scratch family zinc finger 1 2.15175
TBXA2R thromboxane A2 receptor 2.13719
PMP22 peripheral myelin protein 22 2.1362
KRT32 keratin 32, type I 2.1352
CD200R1 CD200 receptor 1 2.12705
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.1211
ALOX15 arachidonate 15-lipoxygenase 2.11445
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.10827
IRF7 interferon regulatory factor 7 2.10385
USP18 ubiquitin specific peptidase 18 2.1037
VN1R1 vomeronasal 1 receptor 1 2.1033
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.09435
MCHR1 melanin-concentrating hormone receptor 1 2.09315
SLC22A14 solute carrier family 22, member 14 2.087
WNT4 wingless-type MMTV integration site family, member 4 2.07935
SPON2 spondin 2, extracellular matrix protein 2.06285
CPE carboxypeptidase E 2.05512
PPP6R1 protein phosphatase 6, regulatory subunit 1 2.05485
DRG2 developmentally regulated GTP binding protein 2 2.04533
ZBP1 Z-DNA binding protein 1 2.0423
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.04215
CRYBA2 crystallin, beta A2 2.0418
CUZD1 CUB and zona pellucida-like domains 1 2.03625
ADAM20 ADAM metallopeptidase domain 20 2.03285
PDE7B phosphodiesterase 7B 2.03115
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.0278
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.00835
WNT7A wingless-type MMTV integration site family, member 7A 2.0069
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.0063
ZNF202 zinc finger protein 202 2.0031
SYT5 synaptotagmin V 2.003
IGHMBP2 immunoglobulin mu binding protein 2 2.0004

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.8632
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.70095
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.6109
EIF5 eukaryotic translation initiation factor 5 -4.12078
TLCD3A TLC domain containing 3A -3.0194
PTPRK protein tyrosine phosphatase, receptor type, K -2.63135
FBXO7 F-box protein 7 -2.5311
SENP6 SUMO1/sentrin specific peptidase 6 -2.48965
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.48353
TCEAL4 transcription elongation factor A (SII)-like 4 -2.4189
HEATR1 HEAT repeat containing 1 -2.392
PRPF4 pre-mRNA processing factor 4 -2.2502
ELP3 elongator acetyltransferase complex subunit 3 -2.18235
ARL4A ADP-ribosylation factor-like 4A -2.16845
HLA-DMA major histocompatibility complex, class II, DM alpha -2.04515