| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN011_HEPG2_24H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 10.0 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 6.9127 |
| GPER1 | G protein-coupled estrogen receptor 1 | 6.2193 |
| UBQLN2 | ubiquilin 2 | 5.9322 |
| CHMP6 | charged multivesicular body protein 6 | 5.93155 |
| MYLK | myosin light chain kinase | 5.67635 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.18345 |
| NOTCH1 | notch 1 | 5.0295 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.95215 |
| STIMATE | STIM activating enhancer | 4.80555 |
| SQOR | sulfide quinone oxidoreductase | 4.7046 |
| ZNF589 | zinc finger protein 589 | 4.41568 |
| CYCS | cytochrome c, somatic | 4.23365 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.7303 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.6641 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.65525 |
| ATP11B | ATPase, class VI, type 11B | 3.4408 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.19702 |
| MEST | mesoderm specific transcript | 3.0176 |
| KIF5C | kinesin family member 5C | 2.99482 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.8193 |
| GPATCH8 | G patch domain containing 8 | 2.79045 |
| CHEK2 | checkpoint kinase 2 | 2.52988 |
| PMM2 | phosphomannomutase 2 | 2.3244 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.32125 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.309 |
| COG4 | component of oligomeric golgi complex 4 | 2.2945 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | 2.19825 |
| LOC127933115 | uncharacterized LOC127933115 | 2.1708 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 2.1683 |
| LOC122526780 | uncharacterized LOC122526780 | 2.1668 |
| MAGT1 | magnesium transporter 1 | 2.1581 |
| TBCCD1 | TBCC domain containing 1 | 2.14965 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.13133 |
| DUOX2 | dual oxidase 2 | 2.11145 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 2.10075 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.08865 |
| LMBRD1 | LMBR1 domain containing 1 | 2.0653 |
| MGP | matrix Gla protein | 2.03525 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.034 |
| RAB21 | RAB21, member RAS oncogene family | 2.02985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VAT1 | vesicle amine transport 1 | -10.0 |
| ZNF586 | zinc finger protein 586 | -6.66735 |
| DNM1L | dynamin 1-like | -6.3508 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.02305 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.8534 |
| TP53BP2 | tumor protein p53 binding protein 2 | -4.73005 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.6426 |
| HAT1 | histone acetyltransferase 1 | -4.56175 |
| SLC35F2 | solute carrier family 35, member F2 | -4.1322 |
| ZNF134 | zinc finger protein 134 | -3.71155 |
| WASHC4 | WASH complex subunit 4 | -3.33122 |
| GNAS | GNAS complex locus | -3.29931 |
| SESN1 | sestrin 1 | -3.0596 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.98215 |
| CCNB2 | cyclin B2 | -2.8757 |
| TLCD3A | TLC domain containing 3A | -2.78835 |
| ZNF211 | zinc finger protein 211 | -2.55215 |
| ZNF587B | zinc finger protein 587B | -2.47965 |
| ZNF304 | zinc finger protein 304 | -2.42935 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.39775 |
| PRPF4 | pre-mRNA processing factor 4 | -2.3395 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.3353 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.3245 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -2.29262 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.2814 |
| ANKRD28 | ankyrin repeat domain 28 | -2.27935 |
| MEMO1 | mediator of cell motility 1 | -2.27705 |
| ZNF419 | zinc finger protein 419 | -2.26573 |
| DUSP10 | dual specificity phosphatase 10 | -2.25402 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.253 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -2.24885 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.22922 |
| ZNF551 | zinc finger protein 551 | -2.16095 |
| IFT81 | intraflagellar transport 81 | -2.15315 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -2.0915 |
| APOD | apolipoprotein D | -2.0808 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -2.07435 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.06575 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.0567 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.0488 |
